about
DNA2:BLM:TOP3A:RMI1:RMI2DNA2:WRNProcessive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:dna2Recruitment of Dna2 endonucleaseRemoval of RNA primer and dissociation of RPA and Dna2Recruitment of Dna2 endonuclease to the C strandRemoval of RNA primer and dissociation of RPA and Dna2 from the C-strand
P527
P688
Acetylation of Dna2 endonuclease/helicase and flap endonuclease 1 by p300 promotes DNA stability by creating long flap intermediatesBLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repairHuman DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediatesIsolation of human Dna2 endonuclease and characterization of its enzymatic propertiesBiochemical analysis of human Dna2Human Dna2 is a nuclear and mitochondrial DNA maintenance proteinBiochemical analyses indicate that binding and cleavage specificities define the ordered processing of human Okazaki fragments by Dna2 and FEN1Okazaki fragment processing-independent role for human Dna2 enzyme during DNA replicationMammalian DNA2 helicase/nuclease cleaves G-quadruplex DNA and is required for telomere integrity
P921
Q50250629-7AD5ACD3-BB78-480A-B218-D879F5FC6ADAQ50250637-14DE7B52-DF22-40C3-906C-34843BCF3C94Q50250979-147790CD-8113-4091-BDB4-13E39A6487F0Q50251534-FD9F8E31-7A38-48D0-9090-6C4A9D87934EQ50286081-724493DA-CE4B-4854-B0A7-7536E1F8684CQ50286082-947FDF00-14A4-4269-A66C-E697EE3C9364Q50286331-D9F0C93A-AFFB-40AE-89B1-34415F9A0B1CQ50286332-243B454B-4E31-4B47-A3A8-C1BC21A4333B
P527
Q24292838-0A321F1F-9490-4BDC-B0C7-77D6A11DE317Q24293244-2FF124C6-7C4B-4A57-BADD-5E0292A9F17BQ24312975-142E816D-BCA1-42C2-96A0-DA0E08831AF7Q24314558-84915456-A07A-4FE6-922D-F47840F3B357Q24314609-50507AB5-84E8-499D-9855-643225EE163BQ24316108-7D05AE27-B028-4E2E-BDBD-BA000603932FQ24319140-E72A1A80-ECF2-4BFA-95C7-0877F68ADA0FQ24319178-5CCAC3F1-D6B7-44CE-A4C3-F693CAD34692Q28118339-E720B14A-B4B8-478A-ABA6-0DED132B07CC
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in DNA replication helicase/nuclease 2
@nl
protèin
@ace
بروتين في الإنسان العاقل
@ar
name
DNA replication helicase/nuclease 2
@en
type
label
DNA replication helicase/nuclease 2
@en
altLabel
DNA replication ATP-dependent helicase-like homolog
@en
DNA replication ATP-dependent helicase/nuclease DNA2
@en
DNA replication helicase 2 homolog
@en
DNA2 DNA replication helicase 2-like
@en
DNA2
@en
DNA2-like helicase
@en
prefLabel
DNA replication helicase/nuclease 2
@en
P637
P680
P681
P682
P705
P352
P638
P2888
P31
P352
P637
NP_001073918
XP_006717743
XP_011537719
XP_016871288
P680
P681
P682
P702
P703
P705
ENSP00000351185
ENSP00000382132
ENSP00000382133
ENSP00000389713
ENSP00000450014
ENSP00000450393