about
P688
Targeting of pro-apoptotic TLR adaptor SARM to mitochondria: definition of the critical region and residues in the signal sequenceSARM1 activation triggers axon degeneration locally via NAD⁺ destructionSARM1-specific motifs in the TIR domain enable NAD+ loss and regulate injury-induced SARM1 activation.The SARM1 Toll/Interleukin-1 Receptor Domain Possesses Intrinsic NAD+ Cleavage Activity that Promotes Pathological Axonal Degeneration.A Cell-Permeant Mimetic of NMN Activates SARM1 to Produce Cyclic ADP-Ribose and Induce Non-apoptotic Cell DeathNAD+ cleavage activity by animal and plant TIR domains in cell death pathwaysTIR domains of plant immune receptors are NAD+-cleaving enzymes that promote cell death
P921
Q24299063-CA3E0016-F43D-4AC7-8D63-F97BA04624ECQ35886152-627A867F-ED06-4B3A-AED2-C293BA897106Q37346739-791D96EE-E7BE-4724-9AF0-236CCF71822BQ47581945-AB107493-6A47-4648-AABD-CC993ECCA829Q64278443-816AB93B-4041-4E1E-A56F-38E2E193BD07Q92796488-0896CDFE-28DE-4678-8730-1405836ECCF5Q92796506-4E1DD8CA-540A-4C1B-B5ED-44B71778B2C7
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
proteinë
@sq
proteïne in Sterile alpha and TIR motif containing 1
@nl
protèin
@ace
بروتين في الإنسان العاقل
@ar
name
Sterile alpha and TIR motif containing 1
@en
type
label
Sterile alpha and TIR motif containing 1
@en
altLabel
MyD88-5
@en
NAD(+) hydrolase SARM1
@en
NADP(+) hydrolase SARM1
@en
NADase SARM1
@en
SAM domain-containing protein 2
@en
SARM1
@en
sterile alpha and Armadillo repeat protein
@en
sterile alpha and HEAT/Armadillo motif protein, ortholog of Drosophila
@en
sterile alpha and TIR motif-containing protein 1
@en
sterile alpha motif domain-containing protein 2
@en
prefLabel
Sterile alpha and TIR motif containing 1
@en
P681
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ENSP00000462228
ENSP00000462479
ENSP00000464166
ENSP00000468032