Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells
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Overcoming Hypoxia-Mediated Tumor Progression: Combinatorial Approaches Targeting pH Regulation, Angiogenesis and Immune DysfunctionMetabolic communication in tumors: a new layer of immunoregulation for immune evasionEvading anti-angiogenic therapy: resistance to anti-angiogenic therapy in solid tumorsReevaluating Metabolism in Alzheimer's Disease from the Perspective of the Astrocyte-Neuron Lactate Shuttle ModelEndothelial Progenitor Cells Physiology and Metabolic Plasticity in Brain Angiogenesis and Blood-Brain Barrier ModelingReexamining cancer metabolism: Lactate production for carcinogenesis could be the purpose and explanation of the Warburg effectLactate as a Signaling Molecule That Regulates Exercise-Induced AdaptationsHypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H(+) symportersKinome Screen Identifies PFKFB3 and Glucose Metabolism as Important Regulators of the Insulin/Insulin-like Growth Factor (IGF)-1 Signaling PathwayModeling Alveolar Soft Part Sarcomagenesis in the Mouse: A Role for Lactate in the Tumor MicroenvironmentRadiosynthesis and validation of (±)-[18F]-3-fluoro-2-hydroxypropionate ([18F]-FLac) as a PET tracer of lactate to monitor MCT1-dependent lactate uptake in tumorsOverexpression of the human DEK oncogene reprograms cellular metabolism and promotes glycolysisCell surface lactate receptor GPR81 is crucial for cancer cell survival.Catabolism of exogenous lactate reveals it as a legitimate metabolic substrate in breast cancer.Evaluation of a hypoxia regulated gene panel in ovarian cancer.Lactate promotes PGE2 synthesis and gluconeogenesis in monocytes to benefit the growth of inflammation-associated colorectal tumor.Lactate does not activate NF-κB in oxidative tumor cellsInhibition of the pentose phosphate pathway by dichloroacetate unravels a missing link between aerobic glycolysis and cancer cell proliferation.Lactate promotes glutamine uptake and metabolism in oxidative cancer cells.Type 2 Diabetes Dysregulates Glucose Metabolism in Cardiac Progenitor CellsMetabolic coupling in urothelial bladder cancer compartments and its correlation to tumor aggressiveness.Lactate engages receptor tyrosine kinases Axl, Tie2, and vascular endothelial growth factor receptor 2 to activate phosphoinositide 3-kinase/Akt and promote angiogenesis.Lactobacilli Modulate Hypoxia-Inducible Factor (HIF)-1 Regulatory Pathway in Triple Negative Breast Cancer Cell Line.Monocarboxylate transporters in the brain and in cancer.Is exercise-in-a-bottle likely to proffer new insights into Alzheimer's disease?Glutamine activates STAT3 to control cancer cell proliferation independently of glutamine metabolism.Mathematical modeling links Wnt signaling to emergent patterns of metabolism in colon cancer.Mitochondrial composition and function under the control of hypoxia.Targeting lactate metabolism for cancer therapeutics.Monocarboxylic acid transport.Metabolism of stromal and immune cells in health and disease.Vascular endothelial growth factors: multitasking functionality in metabolism, health and disease.Lactate and cancer: revisiting the warburg effect in an era of lactate shuttlingMetabolic changes associated with tumor metastasis, part 1: tumor pH, glycolysis and the pentose phosphate pathway.Cross-talk between signaling and metabolism in the vasculature.Modeling the Genetic Regulation of Cancer Metabolism: Interplay between Glycolysis and Oxidative Phosphorylation.Assessment of carbonic anhydrase IX expression and extracellular pH in B-cell lymphoma cell line modelsReprogramming of tumor metabolism by targeting mitochondria improves tumor response to irradiation.Cell-surface G-protein-coupled receptors for tumor-associated metabolites: A direct link to mitochondrial dysfunction in cancer.Metabolic Interactions in the Tumor Microenvironment.
P2860
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P2860
Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells
@ast
Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells
@en
Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells
@en-gb
Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells
@nl
type
label
Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells
@ast
Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells
@en
Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells
@en-gb
Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells
@nl
altLabel
Lactate Activates HIF-1 in Oxidative but Not in Warburg-Phenotype Human Tumor Cells
@en
prefLabel
Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells
@ast
Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells
@en
Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells
@en-gb
Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells
@nl
P2093
P2860
P3181
P1433
P1476
Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells
@en
P2093
Christophe J De Saedeleer
Julien Verrax
Olivier Feron
Tamara Copetti
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0046571
P407
P577
2012-01-01T00:00:00Z