Alternative splicing events are a late feature of pathology in a mouse model of spinal muscular atrophy - Wikidata - wikimedia - TriplyDB

Alternative splicing events are a late feature of pathology in a mouse model of spinal muscular atrophy

Alternative splicing events are a late feature of pathology in a mouse model of spinal muscular atrophy

http://www.wikidata.org/entity/Q21144988

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Survival motor neuron protein regulates stem cell division, proliferation, and differentiation in Drosophila The contribution of mouse models to understanding the pathogenesis of spinal muscular atrophy Is spinal muscular atrophy a disease of the motor neurons only: pathogenesis and therapeutic implications?Spinal muscular atrophy: from gene discovery to clinical trials Spinal muscular atrophy: development and implementation of potential treatments iPSC-Based Models to Unravel Key Pathogenetic Processes Underlying Motor Neuron Disease Development Splicing therapy for neuromuscular disease Genetic correction of human induced pluripotent stem cells from patients with spinal muscular atrophy.SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination Arrhythmia and cardiac defects are a feature of spinal muscular atrophy model mice.New Arabidopsis thaliana cytochrome c partners: a look into the elusive role of cytochrome c in programmed cell death in plants Chondrolectin affects cell survival and neuronal outgrowth in in vitro and in vivo models of spinal muscular atrophy A role for SMN exon 7 splicing in the selective vulnerability of motor neurons in spinal muscular atrophy SMN in spinal muscular atrophy and snRNP biogenesis Somatic Therapy of a Mouse SMA Model with a U7 snRNA Gene Correcting SMN2 Splicing Small nuclear RNAs and mRNAs: linking RNA processing and transport to spinal muscular atrophy.Spinal Muscular Atrophy: From Defective Chaperoning of snRNP Assembly to Neuromuscular Dysfunction.Mouse survival motor neuron alleles that mimic SMN2 splicing and are inducible rescue embryonic lethality early in development but not late The Survival of Motor Neuron Protein Acts as a Molecular Chaperone for mRNP Assembly Specific splicing defects in S. pombe carrying a degron allele of the Survival of Motor Neuron gene Invertebrate models of spinal muscular atrophy: insights into mechanisms and potential therapeutics.Quality control of assembly-defective U1 snRNAs by decapping and 5'-to-3' exonucleolytic digestion.Assays for the identification and prioritization of drug candidates for spinal muscular atrophy ROCK inhibition as a therapy for spinal muscular atrophy: understanding the repercussions on multiple cellular targets Conserved requirement for DEAD-box RNA helicase Gemin3 in Drosophila oogenesis Temporal requirement for high SMN expression in SMA mice A single administration of morpholino antisense oligomer rescues spinal muscular atrophy in mouse SMN-inducing compounds for the treatment of spinal muscular atrophy.Antisense oligonucleotides for the treatment of spinal muscular atrophy.A feedback loop regulates splicing of the spinal muscular atrophy-modifying gene, SMN2.GEMINs: potential therapeutic targets for spinal muscular atrophy?Subcellular transcriptome alterations in a cell culture model of spinal muscular atrophy point to widespread defects in axonal growth and presynaptic differentiation.Spinal Muscular Atrophy Therapeutics: Where do we Stand?Regulation of alternative splicing by the core spliceosomal machinery.Increased IGF-1 in muscle modulates the phenotype of severe SMA mice Alternative splicing dysregulation secondary to skeletal muscle regeneration.Spinal muscular atrophy: from tissue specificity to therapeutic strategies Human motor neuron progenitor transplantation leads to endogenous neuronal sparing in 3 models of motor neuron loss.The Gemin associates of survival motor neuron are required for motor function in Drosophila.SpliceTrap: a method to quantify alternative splicing under single cellular conditions.

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P2860

Alternative splicing events are a late feature of pathology in a mouse model of spinal muscular atrophy

http://www.wikidata.org/entity/Q21144988

description

2009 nî lūn-bûn

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2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年论文

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Alternative splicing events ar ...... del of spinal muscular atrophy

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Alternative splicing events ar ...... del of spinal muscular atrophy

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Alternative splicing events ar ...... del of spinal muscular atrophy

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Alternative splicing events ar ...... del of spinal muscular atrophy

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Alternative splicing events ar ...... del of spinal muscular atrophy

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Alternative splicing events ar ...... del of spinal muscular atrophy

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Alternative splicing events ar ...... del of spinal muscular atrophy

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Alternative splicing events ar ...... del of spinal muscular atrophy

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Dirk Bäumer

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George Nicholson

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Joanna L Davies

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Kay E Davies

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Lyndsay M Murray

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Nicholas J Parkinson

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Olaf Ansorge

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Sheena Lee

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P2860

Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data.

U12DB: a database of orthologous U12-type spliceosomal introns

A functional interaction between the survival motor neuron complex and RNA polymerase II

Summaries of Affymetrix GeneChip probe level data

The survival motor neuron protein interacts with the transactivator FUSE binding protein from human fetal brain

Specific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: a role for Smn in RNA processing in motor axons?

Smn, the spinal muscular atrophy-determining gene product, modulates axon growth and localization of beta-actin mRNA in growth cones of motoneurons

Identification and characterization of a spinal muscular atrophy-determining gene

A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy

Identification of survival motor neuron as a transcriptional activator-binding protein.

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e1000773

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3004414

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10.1371/JOURNAL.PGEN.1000773

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12

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Thomas H. Gillingwater

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2009-12-01T00:00:00Z

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40697094

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20019802

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spinal muscular atrophy

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2787017

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