Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma - Wikidata - wikimedia - TriplyDB

Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma

Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma

http://www.wikidata.org/entity/Q21145827

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Triclosan induces thymic stromal lymphopoietin in skin promoting Th2 allergic responses Atopic Dermatitis and Respiratory Allergy: What is the Link The importance of TSLP in allergic disease and its role as a potential therapeutic target Epidermal permeability barrier defects and barrier repair therapy in atopic dermatitis Skin exposure and asthma: is there a connection?Chronic itch development in sensory neurons requires BRAF signaling pathways.Interleukin-7 and Immunosenescence.Circulating TSLP associates with decreased wheezing in non-atopic preschool children: data from the URECA birth cohort Intradermal administration of IL-33 induces allergic airway inflammation Mast cells in atopic dermatitis A potential link between bacterial pathogens and allergic conjunctivitis by dendritic cells.RBPjkappa-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development Thymic stromal lymphopoietin and the pathophysiology of atopic disease.Differentiation imbalance in single oesophageal progenitor cells causes clonal immortalization and field change.Sensing the outside world: TSLP regulates barrier immunity.Keratin 17 promotes epithelial proliferation and tumor growth by polarizing the immune response in skin.A phase I study of daily treatment with a ceramide-dominant triple lipid mixture commencing in neonates Thymic stromal lymphopoietin contributes to myeloid hyperplasia and increased immunoglobulins, but not epidermal hyperplasia, in RabGEF1-deficient mice Epistasis between serine protease inhibitor Kazal-type 5 (SPINK5) and thymic stromal lymphopoietin (TSLP) genes contributes to childhood asthma The role of thymic stromal lymphopoietin (TSLP) in allergic disorders.The Atopic March: Progression from Atopic Dermatitis to Allergic Rhinitis and Asthma.TSLP promotes induction of Th2 differentiation but is not necessary during established allergen-induced pulmonary disease.Tight junction defects in patients with atopic dermatitis.The absence of a microbiota enhances TSLP expression in mice with defective skin barrier but does not affect the severity of their allergic inflammation Asthma and allergic inflammation.TLR-mediated induction of pro-allergic cytokine IL-33 in ocular mucosal epithelium.TSLP is differentially regulated by vitamin D3 and cytokines in human skin.Lung dendritic cells at the innate-adaptive immune interface.Molecular, genetic, and cellular bases for treating eosinophilic esophagitis.Identification of novel immune and barrier genes in atopic dermatitis by means of laser capture microdissection.Thymic stromal lymphopoietin variation, filaggrin loss of function, and the persistence of atopic dermatitis IRF6 is a mediator of Notch pro-differentiation and tumour suppressive function in keratinocytes.Airway epithelial SPDEF integrates goblet cell differentiation and pulmonary Th2 inflammation.IL-25 and IL-33 Contribute to Development of Eosinophilic Airway Inflammation in Epicutaneously Antigen-Sensitized Mice HPV16 E7 expression in skin induces TSLP secretion, type 2 ILC infiltration and atopic dermatitis-like lesions.Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin Thymic stromal lymphopoietin (TSLP)-mediated dermal inflammation aggravates experimental asthma.Functions of thymic stromal lymphopoietin in immunity and disease.Nrf2 links epidermal barrier function with antioxidant defense Asthma as a chronic disease of the innate and adaptive immune systems responding to viruses and allergens

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Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma

http://www.wikidata.org/entity/Q21145827

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2009 nî lūn-bûn

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2009 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2009 թվականի մայիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma

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Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma

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Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma

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Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma

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Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma

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Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma

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Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma

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Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma

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Skin-Derived TSLP Triggers Progression from Epidermal-Barrier Defects to Asthma

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Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma

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Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma

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Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma

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Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma

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JOURNAL.PBIO.1000067

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Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma

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Mitsuru Morimoto

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Shadmehr Demehri

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P2860

Notch-deficient skin induces a lethal systemic B-lymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrity

Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis

Filaggrin null mutations are associated with increased asthma severity in children and young adults

Canonical notch signaling functions as a commitment switch in the epidermal lineage

Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice

gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis

The global burden of asthma: executive summary of the GINA Dissemination Committee report

Anchoring notch genetics and biochemistry; structural analysis of the ankyrin domain sheds light on existing data.

Cloning of the murine thymic stromal lymphopoietin (TSLP) receptor: Formation of a functional heteromeric complex requires interleukin 7 receptor.

Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition

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Michael J Holtzman

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