PHF8 activates transcription of rRNA genes through H3K4me3 binding and H3K9me1/2 demethylationThe chromatin remodelling complex WSTF-SNF2h interacts with nuclear myosin 1 and has a role in RNA polymerase I transcriptionThe chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription.Multiple interactions between RNA polymerase I, TIF-IA and TAF(I) subunits regulate preinitiation complex assembly at the ribosomal gene promoterMammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcriptionmTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availabilityTFIIH plays an essential role in RNA polymerase I transcription.Activation of RNA polymerase I transcription by cockayne syndrome group B protein and histone methyltransferase G9aReversible acetylation of the chromatin remodelling complex NoRC is required for non-coding RNA-dependent silencingThe nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcriptionThe NoRC complex mediates the heterochromatin formation and stability of silent rRNA genes and centromeric repeatsGenetic inactivation of the transcription factor TIF-IA leads to nucleolar disruption, cell cycle arrest, and p53-mediated apoptosisThe structure of NoRC-associated RNA is crucial for targeting the chromatin remodelling complex NoRC to the nucleolusIntergenic transcripts regulate the epigenetic state of rRNA genesThe PHD finger/bromodomain of NoRC interacts with acetylated histone H4K16 and is sufficient for rDNA silencingCSB is a component of RNA pol I transcriptionThe chromatin remodelling complex NoRC safeguards genome stability by heterochromatin formation at telomeres and centromeres.TAF12 recruits Gadd45a and the nucleotide excision repair complex to the promoter of rRNA genes leading to active DNA demethylation.Human Cdc14B promotes progression through mitosis by dephosphorylating Cdc25 and regulating Cdk1/cyclin B activity.The chromatin remodeling complex NoRC and TTF-I cooperate in the regulation of the mammalian rRNA genes in vivoAcetylation of UBF changes during the cell cycle and regulates the interaction of UBF with RNA polymerase I.NuRD blocks reprogramming of mouse somatic cells into pluripotent stem cells.Intergenic transcripts originating from a subclass of ribosomal DNA repeats silence ribosomal RNA genes in trans.Wisely chosen paths--regulation of rRNA synthesis: delivered on 30 June 2010 at the 35th FEBS Congress in Gothenburg, Sweden.A kinetic framework for a mammalian RNA polymerase in vivo.Life on a planet of its own: regulation of RNA polymerase I transcription in the nucleolus.Epigenetic control of RNA polymerase I transcription in mammalian cells.Role of pescadillo and upstream binding factor in the proliferation and differentiation of murine myeloid cells.The nucleolus—guardian of cellular homeostasis and genome integrity.Long noncoding RNA TARID directs demethylation and activation of the tumor suppressor TCF21 via GADD45A.Actin and myosin as transcription factors.The RNA polymerase I transcription machinery: an emerging target for the treatment of cancer.Autoantibodies to NOR 90/hUBF: longterm clinical and serological followup in a patient with limited systemic sclerosis suggests an antigen driven immune response.Chromatin-specific regulation of mammalian rDNA transcription by clustered TTF-I binding sitesEpigenetic silencing of RNA polymerase I transcription.Death-effector domain-containing protein DEDD is an inhibitor of mitotic Cdk1/cyclin B1.Cooperative Action of Cdk1/cyclin B and SIRT1 Is Required for Mitotic Repression of rRNA Synthesis.Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cellsThe chromatin remodeling complex NuRD establishes the poised state of rRNA genes characterized by bivalent histone modifications and altered nucleosome positionsCellular stress and nucleolar function.
P50
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P50
description
Duits celbioloog
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German cell biologist
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biologiste cellulaire allemande
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citóloga alemana
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deutsche Molekular- und Zellbiologin
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Ingrid Grummt
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Ingrid Grummt
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Ingrid Grummt
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Ingrid Grummt
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Ingrid Grummt
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Ingrid Grummt
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Ingrid Grummt
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Ingrid Grummt
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Ingrid Grummt
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Ingrid Grummt
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Ingrid Grummt
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Ingrid Grummt
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Ingrid Grummt
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Ingrid Grummt
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Ingrid Grummt
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Ingrid Grummt
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Ingrid Grummt
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Ingrid Grummt
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Ingrid Grummt
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Ingrid Grummt
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Ingrid Grummt
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Ingrid Grummt
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Ingrid Grummt
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Ingrid Grummt
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Ingrid Grummt
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Ingrid Grummt
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Ingrid Grummt
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P166
P214
P227
P106
P166
P2080
P21
P214
P227
P31
P5463
Grummt_Ingrid
P569
1943-11-26T00:00:00Z
P735
P7859
viaf-161199985