Ancient exaptation of a CORE-SINE retroposon into a highly conserved mammalian neuronal enhancer of the proopiomelanocortin gene
about
Exaptation of an ancient Alu short interspersed element provides a highly conserved vitamin D-mediated innate immune response in humans and primatesA mammalian conserved element derived from SINE displays enhancer properties recapitulating Satb2 expression in early-born callosal projection neuronsSVA retrotransposons as potential modulators of neuropeptide gene expressionThe role of DNA insertions in phenotypic differentiation between humans and other primatesThe persistent contributions of RNA to eukaryotic gen(om)e architecture and cellular functionSpaces of the possible: universal Darwinism and the wall between technological and biological innovationTransposable elements: from DNA parasites to architects of metazoan evolutionExaptation of transposable elements into novel cis-regulatory elements: is the evidence always strong?A fish-specific transposable element shapes the repertoire of p53 target genes in zebrafishThe role of Transposable Elements in shaping the combinatorial interaction of Transcription Factors29 mammalian genomes reveal novel exaptations of mobile elements for likely regulatory functions in the human genomeExpansion of CORE-SINEs in the genome of the Tasmanian devilConvergent evolution of two mammalian neuronal enhancers by sequential exaptation of unrelated retroposonsTransposable elements and the evolution of regulatory networksA novel mode of enhancer evolution: the Tal1 stem cell enhancer recruited a MIR element to specifically boost its activityCoordinately Co-opted Multiple Transposable Elements Constitute an Enhancer for wnt5a Expression in the Mammalian Secondary PalateDiscover context-specific combinatorial transcription factor interactions by integrating diverse ChIP-Seq data setsWidespread Exonization of Transposable Elements in Human Coding Sequences is Associated with Epigenetic Regulation of TranscriptionA c-Myc regulatory subnetwork from human transposable element sequences.Considering transposable element diversification in de novo annotation approaches.The genetics of Autism Spectrum Disorders--a guide for clinicians.Prediction of transposable element derived enhancers using chromatin modification profiles.Higher frequency of intron loss from the promoter proximally paused genes of Drosophila melanogaster.A SINE-derived element constitutes a unique modular enhancer for mammalian diencephalic Fgf8The estrogen receptor α colocalizes with proopiomelanocortin in hypothalamic neurons and binds to a conserved motif present in the neuron-specific enhancer nPE2Comparison of ultra-conserved elements in drosophilids and vertebratesPartially redundant enhancers cooperatively maintain Mammalian pomc expression above a critical functional thresholdIslet 1 specifies the identity of hypothalamic melanocortin neurons and is critical for normal food intake and adiposity in adulthoodGenome-wide evolutionary and functional analysis of the Equine Repetitive Element 1: an insertion in the myostatin promoter affects gene expressionAn enhancer from the 8q24 prostate cancer risk region is sufficient to direct reporter gene expression to a subset of prostate stem-like epithelial cells in transgenic mice.Positive selection of co-opted mobile genetic elements in a mammalian gene: If you can't beat them, join themObesity-programmed mice are rescued by early genetic interventionMobile Element Evolution Playing Jigsaw - SINEs in Gastropod and Bivalve Mollusks.Possible involvement of SINEs in mammalian-specific brain formationMetaSINEs: Broad Distribution of a Novel SINE Superfamily in AnimalsFunctional autonomy of distant-acting human enhancers.Enhancer turnover and conserved regulatory function in vertebrate evolution.Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease.Retroelements and their impact on genome evolution and functioning.The double-edged sword of (re)expression of genes by hypomethylating agents: from viral mimicry to exploitation as priming agents for targeted immune checkpoint modulation.
P2860
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P2860
Ancient exaptation of a CORE-SINE retroposon into a highly conserved mammalian neuronal enhancer of the proopiomelanocortin gene
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Ancient exaptation of a CORE-S ...... f the proopiomelanocortin gene
@ast
Ancient exaptation of a CORE-S ...... f the proopiomelanocortin gene
@en
Ancient exaptation of a CORE-S ...... f the proopiomelanocortin gene
@en-gb
Ancient exaptation of a CORE-S ...... f the proopiomelanocortin gene
@nl
type
label
Ancient exaptation of a CORE-S ...... f the proopiomelanocortin gene
@ast
Ancient exaptation of a CORE-S ...... f the proopiomelanocortin gene
@en
Ancient exaptation of a CORE-S ...... f the proopiomelanocortin gene
@en-gb
Ancient exaptation of a CORE-S ...... f the proopiomelanocortin gene
@nl
altLabel
Ancient Exaptation of a CORE-S ...... f the Proopiomelanocortin Gene
@en
prefLabel
Ancient exaptation of a CORE-S ...... f the proopiomelanocortin gene
@ast
Ancient exaptation of a CORE-S ...... f the proopiomelanocortin gene
@en
Ancient exaptation of a CORE-S ...... f the proopiomelanocortin gene
@en-gb
Ancient exaptation of a CORE-S ...... f the proopiomelanocortin gene
@nl
P2093
P2860
P3181
P1433
P1476
Ancient exaptation of a CORE-S ...... f the proopiomelanocortin gene
@en
P2093
Andrea M Santangelo
Flávio S J de Souza
Lucía F Franchini
Malcolm J Low
Marcelo Rubinstein
Viviana F Bumaschny
P2860
P304
P3181
P356
10.1371/JOURNAL.PGEN.0030166
P407
P577
2007-10-01T00:00:00Z