Robust network topologies for generating switch-like cellular responses
about
Increasing signal specificity of the TOL network of Pseudomonas putida mt-2 by rewiring the connectivity of the master regulator XylRA characterization of scale invariant responses in enzymatic networksNetwork Architecture Predisposes an Enzyme to Either Pharmacologic or Genetic Targeting.Models of signalling networks - what cell biologists can gain from them and give to themUltrasensitive response motifs: basic amplifiers in molecular signalling networks.Nuclear to cytoplasmic shuttling of ERK promotes differentiation of muscle stem/progenitor cells.Bacterial sugar utilization gives rise to distinct single-cell behaviours.Quantification of pre-mRNA escape rate and synergy in splicing.RMOD: a tool for regulatory motif detection in signaling network.Modeling heterogeneous responsiveness of intrinsic apoptosis pathwayDynamics of gene circuits shapes evolvabilitySystematic reverse engineering of network topologies: a case study of resettable bistable cellular responses.Signaling cascades transmit information downstream and upstream but unlikely simultaneously.Digital signaling decouples activation probability and population heterogeneity.Robust network topologies for generating oscillations with temperature-independent periods.Coupling between feedback loops in autoregulatory networks affects bistability range, open-loop gain and switching timesFostering synergy between cell biology and systems biology.Network motifs provide signatures that characterize metabolism.Architecture of a minimal signaling pathway explains the T-cell response to a 1 million-fold variation in antigen affinity and dose.Design principles of regulatory networks: searching for the molecular algorithms of the cell.Linear-No-Threshold Default Assumptions are Unwarranted for Cytotoxic Endpoints Independently Triggered by Ultrasensitive Molecular Switches.Fate-Regulating Circuits in Viruses: From Discovery to New Therapy Targets.Cellular Decision Making by Non-Integrative Processing of TLR Inputs.Cellular sensory mechanisms for detecting specific fold-changes in extracellular cues.A genetic bistable switch utilizing nonlinear protein degradation.Design principles for robust oscillatory behavior.Different evolutionary modifications as a guide to rewire two-component systems.Bistability in a model of early B cell receptor activation and its role in tonic signaling and system tunability.Endocytosis as a stabilizing mechanism for tissue homeostasis.Identifying robust hysteresis in networks.Drug treatment efficiency depends on the initial state of activation in nonlinear pathways
P2860
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P2860
Robust network topologies for generating switch-like cellular responses
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Robust network topologies for generating switch-like cellular responses
@ast
Robust network topologies for generating switch-like cellular responses
@en
Robust network topologies for generating switch-like cellular responses
@en-gb
Robust network topologies for generating switch-like cellular responses
@nl
type
label
Robust network topologies for generating switch-like cellular responses
@ast
Robust network topologies for generating switch-like cellular responses
@en
Robust network topologies for generating switch-like cellular responses
@en-gb
Robust network topologies for generating switch-like cellular responses
@nl
altLabel
Robust Network Topologies for Generating Switch-Like Cellular Responses
@en
prefLabel
Robust network topologies for generating switch-like cellular responses
@ast
Robust network topologies for generating switch-like cellular responses
@en
Robust network topologies for generating switch-like cellular responses
@en-gb
Robust network topologies for generating switch-like cellular responses
@nl
P2860
P3181
P1476
Robust network topologies for generating switch-like cellular responses
@en
P2093
Casim A Sarkar
P2860
P304
P3181
P356
10.1371/JOURNAL.PCBI.1002085
P407
P50
P577
2011-06-01T00:00:00Z