about
P688
The mitochondrial serine protease HtrA2/Omi cleaves RIP1 during apoptosis of Ba/F3 cells induced by growth factor withdrawalIAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosisTRAF7 potentiates MEKK3-induced AP1 and CHOP activation and induces apoptosisOptineurin negatively regulates TNFalpha- induced NF-kappaB activation by competing with NEMO for ubiquitinated RIPPhosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammationPellino3 targets RIP1 and regulates the pro-apoptotic effects of TNF-αFADD and caspase-8 control the outcome of autophagic signaling in proliferating T cellsTNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II membersTumour necrosis factor receptor 1 mediates endoplasmic reticulum stress-induced activation of the MAP kinase JNKType I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar TyphimuriumComplementary roles of Fas-associated death domain (FADD) and receptor interacting protein kinase-3 (RIPK3) in T-cell homeostasis and antiviral immunityPeli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine productionCaspase 8 inhibits programmed necrosis by processing CYLDCatalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosiscIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species productionNEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte ApoptosisThe E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosisRIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis.Beyond tumor necrosis factor receptor: TRADD signaling in toll-like receptors.RIPK1 inhibits ZBP1-driven necroptosis during development.Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis.Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation.The long noncoding RNA NRF regulates programmed necrosis and myocardial injury during ischemia and reperfusion by targeting miR-873.RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation.SPATA2 regulates the activation of RIPK1 by modulating linear ubiquitination.Death-domain dimerization-mediated activation of RIPK1 controls necroptosis and RIPK1-dependent apoptosis.RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis.PELI1 Selectively Targets Kinase-Active RIP3 for Ubiquitylation-Dependent Proteasomal Degradation.Overexpression of microRNA-590-3p promotes the proliferation of and inhibits the apoptosis of myocardial cells through inhibition of the NF-κB signaling pathway by binding to RIPK1RIPK1 can mediate apoptosis in addition to necroptosis during embryonic developmentSerine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammationCleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosisUbiquitination of RIPK1 suppresses programmed cell death by regulating RIPK1 kinase activation during embryogenesisK63-linked ubiquitination regulates RIPK1 kinase activity to prevent cell death during embryogenesis and inflammationRIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during developmentMutations that prevent caspase cleavage of RIPK1 cause autoinflammatory diseaseMicroRNA-24-3p Attenuates Myocardial Ischemia/Reperfusion Injury by Suppressing RIPK1 Expression in Mice
P921
Q24298215-F7838C18-014D-47D7-865B-8657EF4E6036Q24300734-689DB31B-818C-47B2-80B4-100A6029C452Q24314392-22971216-A493-40AE-B2D2-8457E83D7D00Q24337587-3BA22939-8E17-48B0-A6F1-CBD7E387F0B4Q24338129-AABE0975-800E-45FD-A26B-CBD8CCC4CF73Q24338172-C50AB822-5716-4F34-A4DA-336A604CA5B7Q24646372-5D65F47D-8950-4C76-9BBF-B6FE1DFE65E3Q28505598-BFC13897-6F56-4D6D-A1CF-724D5EAD92EEQ28508892-6D2C67D6-C32A-4C98-85B2-A05F314033DFQ28508897-BA1EA00F-CD76-4C20-9F86-F75C72F1C439Q28509135-98814374-976C-4542-8D1F-13BAD39AF886Q28511245-0922A57E-7926-4FFC-A72C-5D2405E7CD88Q28584927-DD69E1C3-C3FB-49CE-8F24-68634A637713Q28584976-732A16C9-7DBA-4368-8FFF-8895D339DEA1Q28591258-75F82C43-3F7F-4D1F-BEAE-D8F08913A70BQ28593092-9A7C80DA-03E0-486B-B2EF-F879D6E71174Q28593201-779865B1-1485-4FC1-90A8-685946DCEDC7Q28594624-1A3357CA-94C6-4604-9097-D3C8DEADF230Q33798944-AF28458B-A109-487D-87F5-96DA86D159C9Q34659851-04986F82-5BDE-46AC-8DE0-1255F9D13935Q36843563-DC49C051-FF5C-4409-8402-5C8B02A11282Q40486619-33B9DFE8-BE8B-4B94-84A1-FA7E3759F9CFQ41527499-5087255E-15E6-4540-8409-89523B0FB0BCQ41791638-6BE40011-47DC-48C5-AA49-4E716063F15CQ41985560-5CBAFE3E-87D6-42DE-9037-F2985BAFB99EQ47111857-C5204DDE-BF72-47F5-9AA2-B1AC55553BDBQ47141410-D2E0068C-66CC-4888-A1D7-D80C1012D71AQ50026384-40337162-67BD-466D-AC73-D408D6FD1145Q50663781-32158B9A-2B3A-466E-A97C-A4521AE6C9F9Q54976686-D54D8374-909B-4E46-B877-3F5017901C43Q57463446-CCF05B07-A14F-4624-8211-D543FC8588F9Q64097353-2321D30B-C6DC-4AE6-9C48-6D4C8EDBC81AQ64114402-3EEC1C75-4755-4B7B-A68E-896115E87E10Q90069563-0FD17676-4F11-4BE9-98BD-46DB31634C90Q90100566-28DA5765-56EC-4DD0-923D-5E02BAF32D92Q90100569-A924D8C7-7218-41E4-9DD8-C4DC06D29C39Q91304398-D0338A11-E14E-4E97-A8B2-AD69D7F39F60Q91892511-FC8D7E7E-F009-4A00-B8AB-907768C91484Q93140795-D4C70F9C-11C9-4FB7-9926-46C1FD7F331F
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
proteinë
@sq
proteïne in Receptor (TNFRSF)-interacting serine-threonine kinase 1
@nl
protèin
@ace
بروتين في فأر المنازل
@ar
name
Receptor (TNFRSF)-interacting serine-threonine kinase 1
@en
Receptor
@nl
type
label
Receptor (TNFRSF)-interacting serine-threonine kinase 1
@en
Receptor
@nl
altLabel
RIP-1
@en
Ripk1
@en
cell death protein RIP
@en
receptor-interacting protein 1
@en
receptor-interacting serine/threonine-protein kinase 1
@en
serine/threonine-protein kinase RIP
@en
prefLabel
Receptor (TNFRSF)-interacting serine-threonine kinase 1
@en
Receptor
@nl
P361
P527
P637
P680
P681
P682
P705
P352
P31
P352
P527
P637
NP_001346926
XP_006516672
XP_030103066
P680
P681
P682
P702
P703
P705
ENSMUSP00000021844
ENSMUSP00000128511
ENSMUSP00000129831