about
P688
YAC complementation shows a requirement for Wt1 in the development of epicardium, adrenal gland and throughout nephrogenesisWT1 is a key regulator of podocyte function: reduced expression levels cause crescentic glomerulonephritis and mesangial sclerosisBASP1 is a transcriptional cosuppressor for the Wilms' tumor suppressor protein WT1Wilms tumor suppressor, Wt1, is a transcriptional activator of the erythropoietin geneRegulation of the proto-oncogenes bcl-2 and c-myc by the Wilms' tumor suppressor gene WT1Dynamic interaction between WT1 and BASP1 in transcriptional regulation during differentiationThe Wilms' tumor suppressor gene WT1 is negatively autoregulatedWT1 interacts with the splicing factor U2AF65 in an isoform-dependent manner and can be incorporated into spliceosomesDe novo cardiomyocytes from within the activated adult heart after injuryWT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferationAdrenal development is initiated by Cited2 and Wt1 through modulation of Sf-1 dosageWT1 expression induces features of renal epithelial differentiation in mesenchymal fibroblastsUse of dual section mRNA in situ hybridisation/immunohistochemistry to clarify gene expression patterns during the early stages of nephron development in the embryo and in the mature nephron of the adult mouse kidneyWT1-dependent sulfatase expression maintains the normal glomerular filtration barrierCoronary vessel development requires activation of the TrkB neurotrophin receptor by the Wilms' tumor transcription factor Wt1.Initial differentiation of the metanephric mesenchyme is independent of WT1 and the ureteric budProvide fluoxetine information vital to cliniciansTwo splice variants of the Wilms' tumor 1 gene have distinct functions during sex determination and nephron formationThe Wilms' tumor suppressor Wt1 encodes a transcriptional activator of the class IV POU-domain factor Pou4f2 (Brn-3b)WT-1 is required for early kidney developmentTissue-specific RNAi reveals that WT1 expression in nurse cells controls germ cell survival and spermatogenesisA zinc finger truncation of murine WT1 results in the characteristic urogenital abnormalities of Denys-Drash syndromeWt1 functions in the development of germ cells in addition to somatic cell lineages of the testisNr0b1 and its network partners are expressed early in murine embryos prior to steroidogenic axis organogenesisThe Wilms' tumor gene Wt1 is required for normal development of the retinaNovel markers of early ovarian pre-granulosa cells are expressed in an Sry-like patternDifferential regulation of two sets of mesonephric tubules by WT-1The LIM-only coactivator FHL2 modulates WT1 transcriptional activity during gonadal differentiationThe transcription co-factor CITED2 functions during sex determination and early gonad developmentDeletion of Spata2 by CRISPR/Cas9n causes increased inhibin alpha expression and attenuated fertility in male mice.
P921
Q22009123-1F4FDC46-B1AB-4219-8356-CAFD7E2395E5Q24292676-52B9B0B8-D480-4728-AB3F-A957DB5ECF2DQ24303633-3A82C7E4-6982-4DAC-9B18-360C5687527DQ24304157-860D67A4-E272-43BB-B47C-A5E9DF534DF0Q24313334-A810B9C8-4174-4FEE-BEC3-AC96DCF4A7BEQ24320712-38B83C24-821C-44E6-8973-7F2360B72A1AQ24336026-413A114A-1BEE-40A3-B06B-3005D5ED4D4CQ24596062-5DA7AE41-0070-4401-91A0-3DE1E4B6E6FCQ24605971-8D6EEADC-06AD-4632-81D1-9A421DF03D61Q28255707-0E734B4E-3564-490E-B2B7-9075356E7EDDQ28304398-C3C77D1B-84BE-4310-A447-F08B122DDBFBQ28505651-5F42B05F-2645-42CF-9F9E-C7836E50F15FQ28505986-A3E8E8B2-4A9F-41C0-AED9-B15EEFC9BE49Q28506573-3C60EAFA-7FAE-45EA-B50B-850499BC7E96Q28507412-2F09791B-AC01-473F-BE18-C6218ABCF283Q28507716-4FD4C797-3148-471D-B2B1-FFB29A353F7AQ28508124-A0E24900-030C-49ED-88F2-7888998C8B09Q28509874-556D828C-AFB8-4F96-A98A-B689DAB53DA2Q28511422-634A9A0F-386A-4933-B0BD-FE514B818F69Q28512266-BAB5EFD0-E17A-48BA-ABB7-43C1EF711E0CQ28513320-C1B2FD34-8955-42CE-B2F1-D9E8876F2B5BQ28584838-479F2BDF-D86C-4ED9-B7E8-19C3B25CEFD1Q28585638-400FF9C5-170C-40F3-A4E2-E82E8B92CD2CQ28586475-A7805ED7-E8D5-4B8F-85A1-59D4067F7FACQ28590668-2B5D39F4-0AFF-4180-91F0-52B5928895A5Q28590895-24DB48A0-DF44-4667-AA1D-FCA43EFE7E14Q28592223-7F0BBE98-26CE-49B1-98B1-C22FE483D7ABQ28592984-2A6C362A-1F4C-4AEE-B0F3-7B482C5DCFC6Q28594232-28AFFFC3-FD2B-42F7-86F6-806649E8725FQ47661176-56871C91-BD99-458B-89B4-598B238844F1
P921
description
mouse protein (annotated by UniProtKB/Swiss-Prot P22561)
@en
proteinë
@sq
proteïne
@nl
بروتين في فأر المنازل
@ar
name
Wilms tumor protein homolog
@en
type
label
Wilms tumor protein homolog
@en
prefLabel
Wilms tumor protein homolog
@en