Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1
about
The cloning and analysis of LEK1 identifies variations in the LEK/centromere protein F/mitosin gene familyHuman BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APCAn evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cellsUnstable microtubule capture at kinetochores depleted of the centromere-associated protein CENP-F.Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interferenceSilencing mitosin induces misaligned chromosomes, premature chromosome decondensation before anaphase onset, and mitotic cell death.Tripin/hSgo2 recruits MCAK to the inner centromere to correct defective kinetochore attachmentsCAMP (C13orf8, ZNF828) is a novel regulator of kinetochore-microtubule attachment.Human NUF2 interacts with centromere-associated protein E and is essential for a stable spindle microtubule-kinetochore attachmentCentromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome lossCheckpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complexNovel mitosis-specific phosphorylation of histone H3 at Thr11 mediated by Dlk/ZIP kinaseMicrotubule-dependent changes in assembly of microtubule motor proteins and mitotic spindle checkpoint proteins at PtK1 kinetochoresGene silencing of CENP-E by small interfering RNA in HeLa cells leads to missegregation of chromosomes after a mitotic delayMammalian mad2 and bub1/bubR1 recognize distinct spindle-attachment and kinetochore-tension checkpointsSUMO-2/3 modification and binding regulate the association of CENP-E with kinetochores and progression through mitosisStable hZW10 kinetochore residency, mediated by hZwint-1 interaction, is essential for the mitotic checkpointA new view of the spindle checkpointCheckpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signalingSpindle checkpoint protein Bub1 is required for kinetochore localization of Mad1, Mad2, Bub3, and CENP-E, independently of its kinase activityHuman MPS1 kinase is required for mitotic arrest induced by the loss of CENP-E from kinetochoresIdentification and phylogenetic analysis of Dictyostelium discoideum kinesin proteins.SUMOylation in control of accurate chromosome segregation during mitosisLoss of CENP-F results in distinct microtubule-related defects without chromosomal abnormalities.Centromere protein F includes two sites that couple efficiently to depolymerizing microtubulesDynein/Dynactin-mediated transport of kinetochore components off kinetochores and onto spindle poles induced by nordihydroguaiaretic acidThe spindle checkpoint of budding yeast depends on a tight complex between the Mad1 and Mad2 proteins.MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p.Suppressor analysis of a histone defect identifies a new function for the hda1 complex in chromosome segregation.CTCF Recruits Centromeric Protein CENP-E to the Pericentromeric/Centromeric Regions of Chromosomes through Unusual CTCF-Binding SitesFarnesyl transferase inhibitors block the farnesylation of CENP-E and CENP-F and alter the association of CENP-E with the microtubulesFoxM1 is required for execution of the mitotic programme and chromosome stabilityMolecular targets for tumour progression in gastrointestinal stromal tumours.The MRN-CtIP pathway is required for metaphase chromosome alignment.Protein architecture of the human kinetochore microtubule attachment site.Antitumor activity of an allosteric inhibitor of centromere-associated protein-E.Mitotic kinesin CENP-E promotes microtubule plus-end elongation.BubR1 is modified by sumoylation during mitotic progressionKinetochore kinesin CENP-E is a processive bi-directional tracker of dynamic microtubule tips.
P2860
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P248
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P2860
Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1
description
1998 nî lūn-bûn
@nan
1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Characterization of the kineto ...... ore proteins CENP-F and hBUBR1
@ast
Characterization of the kineto ...... ore proteins CENP-F and hBUBR1
@en
Characterization of the kineto ...... ore proteins CENP-F and hBUBR1
@nl
type
label
Characterization of the kineto ...... ore proteins CENP-F and hBUBR1
@ast
Characterization of the kineto ...... ore proteins CENP-F and hBUBR1
@en
Characterization of the kineto ...... ore proteins CENP-F and hBUBR1
@nl
prefLabel
Characterization of the kineto ...... ore proteins CENP-F and hBUBR1
@ast
Characterization of the kineto ...... ore proteins CENP-F and hBUBR1
@en
Characterization of the kineto ...... ore proteins CENP-F and hBUBR1
@nl
P2860
P921
P3181
P356
P1476
Characterization of the kineto ...... ore proteins CENP-F and hBUBR1
@en
P2093
B T Schaar
P2860
P3181
P356
10.1083/JCB.143.1.49
P407
P577
1998-10-01T00:00:00Z