The germinal center kinase (GCK)-related protein kinases HPK1 and KHS are candidates for highly selective signal transducers of Crk family adapter proteins
about
The CUL7/F-box and WD repeat domain containing 8 (CUL7/Fbxw8) ubiquitin ligase promotes degradation of hematopoietic progenitor kinase 1The Role of Crk Adaptor Proteins in T-Cell Adhesion and MigrationThe adaptor protein Crk in immune responseSignaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKLHematopoietic progenitor kinase 1 is a component of transforming growth factor beta-induced c-Jun N-terminal kinase signaling cascadeInvolvement of hematopoietic progenitor kinase 1 in T cell receptor signalingMultiple interactions of the cytosolic polyproline region of the CD95 ligand: hints for the reverse signal transduction capacity of a death factorLeukocyte-specific adaptor protein Grap2 interacts with hematopoietic progenitor kinase 1 (HPK1) to activate JNK signaling pathway in T lymphocytesThe C-terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motifPAK1 kinase promotes cell motility and invasiveness through CRK-II serine phosphorylation in non-small cell lung cancer cellsMona/Gads SH3C binding to hematopoietic progenitor kinase 1 (HPK1) combines an atypical SH3 binding motif, R/KXXK, with a classical PXXP motif embedded in a polyproline type II (PPII) helixProteomic analysis of proteins surrounding occludin and claudin-4 reveals their proximity to signaling and trafficking networksGab3, a new DOS/Gab family member, facilitates macrophage differentiation.MST3 promotes proliferation and tumorigenicity through the VAV2/Rac1 signal axis in breast cancer.Nck adapter proteins: functional versatility in T cellsProstaglandin E2 activates HPK1 kinase activity via a PKA-dependent pathway.Uncoupling Crk signal transduction by Pseudomonas exoenzyme T.The v-Crk oncogene enhances cell survival and induces activation of protein kinase B/Akt.Herpesvirus ateles gene product Tio interacts with nonreceptor protein tyrosine kinasesProtein phosphatase 4 is a positive regulator of hematopoietic progenitor kinase 1.High affinity molecules disrupting GRB2 protein complexes as a therapeutic strategy for chronic myelogenous leukaemia.Attenuation of T cell receptor signaling by serine phosphorylation-mediated lysine 30 ubiquitination of SLP-76 protein.Activation of hematopoietic progenitor kinase 1 involves relocation, autophosphorylation, and transphosphorylation by protein kinase D1.KFC, a Ste20-like kinase with mitogenic potential and capability to activate the SAPK/JNK pathway.Expression of heat-shock protein 90 in glucocorticoid-sensitive and -resistant childhood acute lymphoblastic leukaemia.Increased C-CRK proto-oncogene expression is associated with an aggressive phenotype in lung adenocarcinomas.Tyrosine phosphorylation of HPK1 by activated Src promotes ischemic brain injury in rat hippocampal CA1 region.
P2860
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P2860
The germinal center kinase (GCK)-related protein kinases HPK1 and KHS are candidates for highly selective signal transducers of Crk family adapter proteins
description
1998 nî lūn-bûn
@nan
1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
The germinal center kinase (GC ...... of Crk family adapter proteins
@ast
The germinal center kinase (GC ...... of Crk family adapter proteins
@en
The germinal center kinase (GC ...... of Crk family adapter proteins
@en-gb
The germinal center kinase (GC ...... of Crk family adapter proteins
@nl
type
label
The germinal center kinase (GC ...... of Crk family adapter proteins
@ast
The germinal center kinase (GC ...... of Crk family adapter proteins
@en
The germinal center kinase (GC ...... of Crk family adapter proteins
@en-gb
The germinal center kinase (GC ...... of Crk family adapter proteins
@nl
prefLabel
The germinal center kinase (GC ...... of Crk family adapter proteins
@ast
The germinal center kinase (GC ...... of Crk family adapter proteins
@en
The germinal center kinase (GC ...... of Crk family adapter proteins
@en-gb
The germinal center kinase (GC ...... of Crk family adapter proteins
@nl
P2093
P356
P1433
P1476
The germinal center kinase (GC ...... of Crk family adapter proteins
@en
P2093
C Kardinal
K Adermann
S M Feller
P2888
P304
P356
10.1038/SJ.ONC.1202108
P407
P577
1998-10-15T00:00:00Z
P5875
P6179
1005500141