CNK, a RAF-binding multidomain protein required for RAS signaling
about
The major vault protein is a novel substrate for the tyrosine phosphatase SHP-2 and scaffold protein in epidermal growth factor signalingHuman CNK1 acts as a scaffold protein, linking Rho and Ras signal transduction pathwaysDensin-180, a synaptic protein, links to PSD-95 through its direct interaction with MAGUIN-1Raf family kinases: old dogs have learned new tricksThe scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell deathMeaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactionsCrystal structure of the p14/MP1 scaffolding complex: how a twin couple attaches mitogen-activated protein kinase signaling to late endosomesHadp1, a newly identified pleckstrin homology domain protein, is required for cardiac contractility in zebrafishA Stat3-interacting protein (StIP1) regulates cytokine signal transductionFunctional analysis of CNK in RAS signalingThe role of the ENaC-regulatory complex in aldosterone-mediated sodium transportOrganization of the ENaC-regulatory machineryCNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signalingLocalization of endogenous Grb10 to the mitochondria and its interaction with the mitochondrial-associated Raf-1 poolEpidermal growth factor treatment enhances the kinase activity of kinase suppressor of RasMAGUIN, a novel neuronal membrane-associated guanylate kinase-interacting proteinErbin suppresses the MAP kinase pathwaySynaptic localization of membrane-associated guanylate kinase-interacting protein mediated by the pleckstrin homology domainDrosophila-raf acts to elaborate dorsoventral pattern in the ectoderm of developing embryosA functional screen reveals an extensive layer of transcriptional and splicing control underlying RAS/MAPK signaling in DrosophilaCoordinating ERK/MAPK signalling through scaffolds and inhibitorsSrc42 binding activity regulates Drosophila RAF by a novel CNK-dependent derepression mechanism.Changes in Notch signaling coordinates maintenance and differentiation of the Drosophila larval optic lobe neuroepithelia.Bioluminescence resonance energy transfer identify scaffold protein CNK1 interactions in intact cells.How Genetics Has Helped Piece Together the MAPK Signaling Pathway.Administration of ricin induces a severe inflammatory response via nonredundant stimulation of ERK, JNK, and P38 MAPK and provides a mouse model of hemolytic uremic syndrome.The CNK2 scaffold interacts with vilse and modulates Rac cycling during spine morphogenesis in hippocampal neurons.The Berkeley Drosophila Genome Project gene disruption project: Single P-element insertions mutating 25% of vital Drosophila genes.Caenorhabditis elegans CNK-1 promotes Raf activation but is not essential for Ras/Raf signalingThe CNK1 scaffold binds cytohesins and promotes insulin pathway signaling.Apical accumulation of the Sevenless receptor tyrosine kinase during Drosophila eye development is promoted by the small GTPase Rap1CNK1 is a scaffold protein that regulates Src-mediated Raf-1 activation.The novel SAM domain protein Aveugle is required for Raf activation in the Drosophila EGF receptor signaling pathwayA Drosophila model of multiple endocrine neoplasia type 2.A misexpression screen identifies genes that can modulate RAS1 pathway signaling in Drosophila melanogasterA genetic screen for modifiers of a kinase suppressor of Ras-dependent rough eye phenotype in Drosophila.A KSR/CNK complex mediated by HYP, a novel SAM domain-containing protein, regulates RAS-dependent RAF activation in Drosophila.The proliferation of Drosophila in cancer research: a system for the functional characterization of tumor suppressors and oncogenes.Functions and mechanisms of receptor tyrosine kinase Torso signaling: lessons from Drosophila embryonic terminal development.Genetic and functional studies implicate synaptic overgrowth and ring gland cAMP/PKA signaling defects in the Drosophila melanogaster neurofibromatosis-1 growth deficiency.
P2860
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P2860
CNK, a RAF-binding multidomain protein required for RAS signaling
description
1998 nî lūn-bûn
@nan
1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
CNK, a RAF-binding multidomain protein required for RAS signaling
@ast
CNK, a RAF-binding multidomain protein required for RAS signaling
@en
CNK, a RAF-binding multidomain protein required for RAS signaling
@en-gb
CNK, a RAF-binding multidomain protein required for RAS signaling
@nl
type
label
CNK, a RAF-binding multidomain protein required for RAS signaling
@ast
CNK, a RAF-binding multidomain protein required for RAS signaling
@en
CNK, a RAF-binding multidomain protein required for RAS signaling
@en-gb
CNK, a RAF-binding multidomain protein required for RAS signaling
@nl
prefLabel
CNK, a RAF-binding multidomain protein required for RAS signaling
@ast
CNK, a RAF-binding multidomain protein required for RAS signaling
@en
CNK, a RAF-binding multidomain protein required for RAS signaling
@en-gb
CNK, a RAF-binding multidomain protein required for RAS signaling
@nl
P2093
P3181
P1433
P1476
CNK, a RAF-binding multidomain protein required for RAS signaling
@en
P2093
P304
P3181
P356
10.1016/S0092-8674(00)81766-3
P407
P577
1998-10-30T00:00:00Z