Identification of a human HECT family protein with homology to the Drosophila tumor suppressor gene hyperplastic discs
about
Regulation of poly(A) binding protein function in translation: Characterization of the Paip2 homolog, Paip2BEDD, the human hyperplastic discs protein, has a role in progesterone receptor coactivation and potential involvement in DNA damage responseStructural basis of ligand recognition by PABC, a highly specific peptide-binding domain found in poly(A)-binding protein and a HECT ubiquitin ligase.The EDD E3 ubiquitin ligase ubiquitinates and up-regulates beta-catenin.Poly(A) binding protein (PABP) homeostasis is mediated by the stability of its inhibitor, Paip2Protein kinase DYRK2 is a scaffold that facilitates assembly of an E3 ligaseA family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons.X-ray structure of the human hyperplastic discs protein: an ortholog of the C-terminal domain of poly(A)-binding proteinStructure and function of the C-terminal PABC domain of human poly(A)-binding proteinStructural basis of ubiquitin recognition by the ubiquitin-associated (UBA) domain of the ubiquitin ligase EDDCooperation of HECT-domain ubiquitin ligase hHYD and DNA topoisomerase II-binding protein for DNA damage responseIdentification of novel ERK2 substrates through use of an engineered kinase and ATP analogsAcetylation regulates gluconeogenesis by promoting PEPCK1 degradation via recruiting the UBR5 ubiquitin ligaseEDD mediates DNA damage-induced activation of CHK2Comparative peptide binding studies of the PABC domains from the ubiquitin-protein isopeptide ligase HYD and poly(A)-binding protein. Implications for HYD functionDeubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cellsEDD enhances cell survival and cisplatin resistance and is a therapeutic target for epithelial ovarian cancer.The substrate recognition domains of the N-end rule pathway.HECT E3s and human disease.The role of Drosophila hyperplastic discs gene in spermatogenesis.Modulation of myocardin function by the ubiquitin E3 ligase UBR5.UBR5-mediated ubiquitination of ATMIN is required for ionizing radiation-induced ATM signaling and function.Specific aspects of the ubiquitin system in spermatogenesis.The proliferation of Drosophila in cancer research: a system for the functional characterization of tumor suppressors and oncogenes.EDD inhibits ATM-mediated phosphorylation of p53.Mammalian hyperplastic discs homolog EDD regulates miRNA-mediated gene silencingA whole-genome RNAi screen identifies an 8q22 gene cluster that inhibits death receptor-mediated apoptosis.Corp Regulates P53 in Drosophila melanogaster via a Negative Feedback Loop.Human Herpesvirus-6 U14 Induces Cell-Cycle Arrest in G2/M Phase by Associating with a Cellular Protein, EDD.The MLLE domain of the ubiquitin ligase UBR5 binds to its catalytic domain to regulate substrate binding.A novel role for RIP1 kinase in mediating TNFα production.UBR5 Gene Mutation Is Associated with Familial Adult Myoclonic Epilepsy in a Japanese Family.The novel interaction between microspherule protein Msp58 and ubiquitin E3 ligase EDD regulates cell cycle progression.The E3 ubiquitin ligase EDD is an adverse prognostic factor for serous epithelial ovarian cancer and modulates cisplatin resistance in vitroDyrk2-associated EDD-DDB1-VprBP E3 ligase inhibits telomerase by TERT degradationEdd, the murine hyperplastic disc gene, is essential for yolk sac vascularization and chorioallantoic fusion.Regulation of poly(A)-binding protein through PABP-interacting proteins.UBR-5, a Conserved HECT-Type E3 Ubiquitin Ligase, Negatively Regulates Notch-Type Signaling in Caenorhabditis elegansE3 ubiquitin ligase isolated by differential display regulates cervical cancer growth in vitro and in vivo via microRNA-143.E3 ubiquitin ligases and human papillomavirus-induced carcinogenesis.
P2860
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P2860
Identification of a human HECT family protein with homology to the Drosophila tumor suppressor gene hyperplastic discs
description
1998 nî lūn-bûn
@nan
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Identification of a human HECT ...... ressor gene hyperplastic discs
@ast
Identification of a human HECT ...... ressor gene hyperplastic discs
@en
Identification of a human HECT ...... ressor gene hyperplastic discs
@en-gb
Identification of a human HECT ...... ressor gene hyperplastic discs
@nl
type
label
Identification of a human HECT ...... ressor gene hyperplastic discs
@ast
Identification of a human HECT ...... ressor gene hyperplastic discs
@en
Identification of a human HECT ...... ressor gene hyperplastic discs
@en-gb
Identification of a human HECT ...... ressor gene hyperplastic discs
@nl
prefLabel
Identification of a human HECT ...... ressor gene hyperplastic discs
@ast
Identification of a human HECT ...... ressor gene hyperplastic discs
@en
Identification of a human HECT ...... ressor gene hyperplastic discs
@en-gb
Identification of a human HECT ...... ressor gene hyperplastic discs
@nl
P2093
P3181
P356
P1433
P1476
Identification of a human HECT ...... ressor gene hyperplastic discs
@en
P2093
A J Russell
E Woollatt
G R Sutherland
M J Callaghan
R L Sutherland
P2888
P304
P3181
P356
10.1038/SJ.ONC.1202249
P407
P577
1998-12-31T00:00:00Z
P5875
P6179
1039366891