Structure and function of the human transcription elongation factor DSIF - Wikidata - wikimedia - TriplyDB

Structure and function of the human transcription elongation factor DSIF

Structure and function of the human transcription elongation factor DSIF

http://www.wikidata.org/entity/Q22009021

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Tat-SF1 protein associates with RAP30 and human SPT5 proteins Human Elongator facilitates RNA polymerase II transcription through chromatin Human transcription elongation factor NELF: identification of novel subunits and reconstitution of the functionally active complex Evidence that negative elongation factor represses transcription elongation through binding to a DRB sensitivity-inducing factor/RNA polymerase II complex and RNA.Spt5 cooperates with human immunodeficiency virus type 1 Tat by preventing premature RNA release at terminator sequences Phosphorylation of the RNA polymerase II carboxyl-terminal domain by CDK9 is directly responsible for human immunodeficiency virus type 1 Tat-activated transcriptional elongation The transcription elongation factor CA150 interacts with RNA polymerase II and the pre-mRNA splicing factor SF1 CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus type 1 tat-P-TEFb complex to TAR RNA Domains in the SPT5 protein that modulate its transcriptional regulatory properties Transcription elongation factor hSPT5 stimulates mRNA capping Human Spt6 stimulates transcription elongation by RNA polymerase II in vitro The Spt4-Spt5 complex: a multi-faceted regulator of transcription elongation Crystal structure of the human transcription elongation factor DSIF hSpt4 subunit in complex with the hSpt5 dimerization interface The Transcription Factor Spn1 Regulates Gene Expression via a Highly Conserved Novel Structural Motif Molecular evidence for a positive role of Spt4 in transcription elongation.The C-terminal repeat domain of Spt5 plays an important role in suppression of Rad26-independent transcription coupled repair.The transcription elongation factor Spt5 influences transcription by RNA polymerase I positively and negatively.The yeast transcription elongation factor Spt4/5 is a sequence-specific RNA binding protein.Biochemical Analysis of Yeast Suppressor of Ty 4/5 (Spt4/5) Reveals the Importance of Nucleic Acid Interactions in the Prevention of RNA Polymerase II Arrest Yeast transcription elongation factor Spt5 associates with RNA polymerase I and RNA polymerase II directly.Spn1 regulates the recruitment of Spt6 and the Swi/Snf complex during transcriptional activation by RNA polymerase II DSIF and NELF interact with RNA polymerase II elongation complex and HIV-1 Tat stimulates P-TEFb-mediated phosphorylation of RNA polymerase II and DSIF during transcription elongation Structure-function analysis of human Spt4: evidence that hSpt4 and hSpt5 exert their roles in transcriptional elongation as parts of the DSIF complex TFIIH inhibits CDK9 phosphorylation during human immunodeficiency virus type 1 transcription Interactions between the aryl hydrocarbon receptor and P-TEFb. Sequential recruitment of transcription factors and differential phosphorylation of C-terminal domain of RNA polymerase II at cyp1a1 promoter PITSLRE p110 protein kinases associate with transcription complexes and affect their activity A highly purified RNA polymerase II elongation control system Phosphorylation of CDK9 at Ser175 enhances HIV transcription and is a marker of activated P-TEFb in CD4(+) T lymphocytes P-TEFb, a cyclin-dependent kinase controlling elongation by RNA polymerase II Positive transcription elongation factor B phosphorylates hSPT5 and RNA polymerase II carboxyl-terminal domain independently of cyclin-dependent kinase-activating kinase.Repression of RNA polymerase II elongation in vivo is critically dependent on the C-terminus of Spt5.Negative elongation factor is required for the maintenance of proviral latency but does not induce promoter-proximal pausing of RNA polymerase II on the HIV long terminal repeat.Insights into how Spt5 functions in transcription elongation and repressing transcription coupled DNA repair.RNA polymerase II transcription elongation and Pol II CTD Ser2 phosphorylation: A tail of two kinases.Formation of a carboxy-terminal domain phosphatase (Fcp1)/TFIIF/RNA polymerase II (pol II) complex in Schizosaccharomyces pombe involves direct interaction between Fcp1 and the Rpb4 subunit of pol II Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5 Novel domains and orthologues of eukaryotic transcription elongation factors.Highly reproducible label free quantitative proteomic analysis of RNA polymerase complexes.The Ras/PKA signaling pathway may control RNA polymerase II elongation via the Spt4p/Spt5p complex in Saccharomyces cerevisiae.P-TEFb kinase recruitment and function at heat shock loci

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Structure and function of the human transcription elongation factor DSIF

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1999 nî lūn-bûn

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1999 թուականի Մարտին հրատարակուած գիտական յօդուած

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1999 թվականի մարտին հրատարակված գիտական հոդված

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1999年の論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年论文

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name

Structure and function of the human transcription elongation factor DSIF

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Structure and function of the human transcription elongation factor DSIF

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Structure and function of the human transcription elongation factor DSIF

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Structure and function of the human transcription elongation factor DSIF

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Structure and function of the human transcription elongation factor DSIF

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Structure and function of the human transcription elongation factor DSIF

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Structure and function of the human transcription elongation factor DSIF

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Structure and function of the human transcription elongation factor DSIF

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Structure and function of the human transcription elongation factor DSIF

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Structure and function of the human transcription elongation factor DSIF

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Structure and function of the human transcription elongation factor DSIF

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Structure and function of the human transcription elongation factor DSIF

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JBC.274.12.8085

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Journal of Biological Chemistry

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Structure and function of the human transcription elongation factor DSIF

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D Watanabe

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H Handa

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J Hasegawa

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T Takagi

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T Wada

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Y Yamaguchi

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P2860

Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro

Identification and analysis of a functional human homolog of the SPT4 gene of Saccharomyces cerevisiae

Identification of multiple cyclin subunits of human P-TEFb

DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs

Functional domains of transcription factor hGABP beta1/E4TF1-53 required for nuclear localization and transcription activation

The scanning model for translation: an update

A simple method for displaying the hydropathic character of a protein

Efficient selection for high-expression transfectants with a novel eukaryotic vector

SPT5, an essential gene important for normal transcription in Saccharomyces cerevisiae, encodes an acidic nuclear protein with a carboxy-terminal repeat.

Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae

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10.1074/JBC.274.12.8085

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10075709

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P921

negative regulation of DNA-templated transcription, elongation

SPT5 homolog, DSIF elongation factor subunit