Novel alternatively spliced isoforms of the neurofibromatosis type 2 tumor suppressor are targeted to the nucleus and cytoplasmic granules
about
Evolution and origin of merlin, the product of the Neurofibromatosis type 2 (NF2) tumor-suppressor geneA neuronal function of the tumor suppressor protein merlinMerlin, a "magic" linker between extracellular cues and intracellular signaling pathways that regulate cell motility, proliferation, and survivalJCV T-antigen interacts with the neurofibromatosis type 2 gene product in a transgenic mouse model of malignant peripheral nerve sheath tumorsA novel alternative splicing isoform of NF2 identified in human Schwann cells.Differential expression proteomics of human colon cancer.Proline oxidase functions as a mitochondrial tumor suppressor in human cancers.Point mutation in the NF2 gene of HEI-193 human schwannoma cells results in the expression of a merlin isoform with attenuated growth suppressive activity.Low Merlin expression and high Survivin labeling index are indicators for poor prognosis in patients with malignant pleural mesothelioma.The merlin tumor suppressor interacts with Ral guanine nucleotide dissociation stimulator and inhibits its activity.The cytoskeletal protein ezrin regulates EC proliferation and angiogenesis via TNF-alpha-induced transcriptional repression of cyclin A.Neurofibromatosis type 2 tumor suppressor protein is expressed in oligodendrocytes and regulates cell proliferation and process formation.
P2860
Q21283962-99B784C1-10B1-4924-AE38-CB11B6CFE79AQ26830181-C47368BF-F8EE-4A40-8FFB-FEEF2C1A9915Q28283076-BA255F5D-C059-4C54-9983-3A8EEDA228BEQ28506719-684974AD-60FC-400C-BCAD-2DA92AC61596Q30378598-83B2342B-00D2-49A6-8EE8-A8068A819F2EQ33232585-2A02B4CE-4B39-48CF-ACD5-C94E0471C63EQ34872984-562FC93F-BF2A-4B97-9EAB-5272F02777ADQ36445494-FDCBD4C0-99E3-4BA0-B82B-63D263A682D9Q40667179-4FCF13C0-9CD9-457B-92BF-CD2EE53D20E6Q42812549-DCFE7B83-B3BD-47DD-96F9-AC61B2FD84C2Q42860390-FE02850F-48DD-4468-B59A-96850EB9F2A3Q55234046-D618A878-F48C-4153-962D-8416ED35CEEE
P2860
Novel alternatively spliced isoforms of the neurofibromatosis type 2 tumor suppressor are targeted to the nucleus and cytoplasmic granules
description
1999 nî lūn-bûn
@nan
1999 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Novel alternatively spliced is ...... cleus and cytoplasmic granules
@ast
Novel alternatively spliced is ...... cleus and cytoplasmic granules
@en
Novel alternatively spliced is ...... cleus and cytoplasmic granules
@en-gb
Novel alternatively spliced is ...... cleus and cytoplasmic granules
@nl
type
label
Novel alternatively spliced is ...... cleus and cytoplasmic granules
@ast
Novel alternatively spliced is ...... cleus and cytoplasmic granules
@en
Novel alternatively spliced is ...... cleus and cytoplasmic granules
@en-gb
Novel alternatively spliced is ...... cleus and cytoplasmic granules
@nl
prefLabel
Novel alternatively spliced is ...... cleus and cytoplasmic granules
@ast
Novel alternatively spliced is ...... cleus and cytoplasmic granules
@en
Novel alternatively spliced is ...... cleus and cytoplasmic granules
@en-gb
Novel alternatively spliced is ...... cleus and cytoplasmic granules
@nl
P2093
P2860
P356
P1476
Novel alternatively spliced is ...... cleus and cytoplasmic granules
@en
P2093
P2860
P304
P356
10.1093/HMG/8.8.1561
P407
P577
1999-08-01T00:00:00Z