Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein
about
A novel link between the proteasome pathway and the signal transduction pathway of the bone morphogenetic proteins (BMPs).Inactivation of menin, a Smad3-interacting protein, blocks transforming growth factor type beta signalingSki-interacting protein interacts with Smad proteins to augment transforming growth factor-beta-dependent transcriptionDACH1 inhibits transforming growth factor-beta signaling through binding Smad4The Ski-binding protein C184M negatively regulates tumor growth factor-beta signaling by sequestering the Smad proteins in the cytoplasmTIMAP, a novel CAAX box protein regulated by TGF-beta1 and expressed in endothelial cellsSumoylated SnoN represses transcription in a promoter-specific mannerThe transforming activity of Ski and SnoN is dependent on their ability to repress the activity of Smad proteinsDownregulation of Ski and SnoN co-repressors by anisomycinArkadia induces degradation of SnoN and c-Ski to enhance transforming growth factor-beta signalingPotentiation of Smad-mediated transcriptional activation by the RNA-binding protein RBPMSCytoplasmic SnoN in normal tissues and nonmalignant cells antagonizes TGF-beta signaling by sequestration of the Smad proteinsOverexpression of SnoN/SkiL, amplified at the 3q26.2 locus, in ovarian cancers: a role in ovarian pathogenesisSKI and MEL1 cooperate to inhibit transforming growth factor-beta signal in gastric cancer cellsHepatitis B virus core protein interacts with CD59 to promote complement-mediated liver inflammation during chronic hepatitis B virus infectionIdentification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1Cloning and functional characterization of a new Ski homolog, Fussel-18, specifically expressed in neuronal tissuesThe integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokinesUSP15 is a deubiquitylating enzyme for receptor-activated SMADsRegulation of TG-interacting factor by transforming growth factor-betaRepression of Smad2 and Smad3 transactivating activity by association with a novel splice variant of CCAAT-binding factor C subunitRequirement for the SnoN oncoprotein in transforming growth factor beta-induced oncogenic transformation of fibroblast cells.Identification of mZnf8, a mouse Krüppel-like transcriptional repressor, as a novel nuclear interaction partner of Smad1.Epidermal growth factor signaling via Ras controls the Smad transcriptional co-repressor TGIF.BF-1 interferes with transforming growth factor beta signaling by associating with Smad partnersRegulation of myostatin activity and muscle growthA novel ability of Smad3 to regulate proteasomal degradation of a Cas family member HEF1Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoNLigand-dependent degradation of Smad3 by a ubiquitin ligase complex of ROC1 and associated proteinsAmplification of Cyclin L1 is associated with lymph node metastases in head and neck squamous cell carcinoma (HNSCC)Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradationTransforming growth factor-beta and breast cancer: Transforming growth factor-beta/SMAD signaling defects and cancer.The functional genomic response of developing embryonic submandibular glands to NF-kappa B inhibitionThe Tgif2 gene contains a retained intron within the coding sequence.HER-2 overexpression differentially alters transforming growth factor-beta responses in luminal versus mesenchymal human breast cancer cellsTGF-β and BMP signaling in osteoblast differentiation and bone formationNudel and FAK as antagonizing strength modulators of nascent adhesions through paxillinRole of TGFβ in regulation of the tumor microenvironment and drug delivery (review)TGFβ Signaling in Tumor Initiation, Epithelial-to-Mesenchymal Transition, and MetastasisInterplay of retinal determination gene network with TGF-β signaling pathway in epithelial-mesenchymal transition
P2860
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P2860
Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein
description
1999 nî lūn-bûn
@nan
1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
name
Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein
@ast
Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein
@en
Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein
@en-gb
Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein
@nl
type
label
Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein
@ast
Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein
@en
Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein
@en-gb
Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein
@nl
prefLabel
Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein
@ast
Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein
@en
Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein
@en-gb
Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein
@nl
P2093
P3181
P1433
P1476
Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein
@en
P2093
P3181
P356
10.1126/SCIENCE.286.5440.771
P407
P577
1999-10-22T00:00:00Z