Fibroblast activation protein, a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts
about
Cloning, expression and chromosomal localization of a novel human dipeptidyl peptidase (DPP) IV homolog, DPP8Neuropeptide Y, B-type natriuretic peptide, substance P and peptide YY are novel substrates of fibroblast activation protein-αThe protease complex consisting of dipeptidyl peptidase IV and seprase plays a role in the migration and invasion of human endothelial cells in collagenous matricesCatalytic properties and inhibition of proline-specific dipeptidyl peptidases II, IV and VIICloning and functional expression of rat kidney dipeptidyl peptidase IICancer-Associated Fibroblasts: Their Characteristics and Their Roles in Tumor GrowthRationale behind targeting fibroblast activation protein-expressing carcinoma-associated fibroblasts as a novel chemotherapeutic strategyInduced-fit mechanism for prolyl endopeptidase.Structure and Catalysis of Acylaminoacyl Peptidase: CLOSED AND OPEN SUBUNITS OF A DIMER OLIGOPEPTIDASEThe application of the fibroblast activation protein α-targeted immunotherapy strategyFibroblast activation protein α in tumor microenvironment: recent progression and implications (review)Identification of selective and potent inhibitors of fibroblast activation protein and prolyl oligopeptidaseRegulation of fibroblast migration on collagenous matrix by a cell surface peptidase complexIntrahepatic expression of the hepatic stellate cell marker fibroblast activation protein correlates with the degree of fibrosis in hepatitis C virus infectionStructural and kinetic analysis of the substrate specificity of human fibroblast activation protein alphaFAPalpha, a surface peptidase expressed during wound healing, is a tumor suppressorIdiopathic pulmonary fibrosis: aberrant recapitulation of developmental programs?FAP-overexpressing fibroblasts produce an extracellular matrix that enhances invasive velocity and directionality of pancreatic cancer cells.Phase I trial of PT-100 (PT-100), a cytokine-inducing small molecule, following chemotherapy for solid tumor malignancy.Selective inhibition of fibroblast activation protein protease based on dipeptide substrate specificity.Fibroblast activation protein peptide substrates identified from human collagen I derived gelatin cleavage sites.Phase II assessment of talabostat and cisplatin in second-line stage IV melanoma.Ionizing radiation abrogates the pro-tumorigenic capacity of cancer-associated fibroblasts co-implanted in xenografts.RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia.Evaluation of the circulating level of fibroblast activation protein α for diagnosis of esophageal squamous cell carcinoma.Analysis of Gene Expression Signatures in Cancer-Associated Stroma from Canine Mammary Tumours Reveals Molecular Homology to Human Breast Carcinomas.Circulating fibroblast activation protein activity and antigen levels correlate strongly when measured in liver disease and coronary heart disease.Cancer and the tumor microenvironment: a review of an essential relationship.Fibroblast activating protein-α expression in squamous cell carcinoma of the esophagus in primary and irradiated tumors: the use of archival FFPE material for molecular techniquesTargeted disruption of mouse fibroblast activation protein.Transcriptional regulation of seprase in invasive melanoma cells by transforming growth factor-β signaling.Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia.Human breast cancer associated fibroblasts exhibit subtype specific gene expression profiles.Identification of inhibitory scFv antibodies targeting fibroblast activation protein utilizing phage display functional screens.Re-directed T cells for the treatment of fibroblast activation protein (FAP)-positive malignant pleural mesothelioma (FAPME-1).Investigation of the dimer interface and substrate specificity of prolyl dipeptidase DPP8.Role of myofibroblasts at the invasion front.Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptakeFibroblast activation protein expression by stromal cells and tumor-associated macrophages in human breast cancer.Targeted inactivation of dipeptidyl peptidase 9 enzymatic activity causes mouse neonate lethality.
P2860
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P2860
Fibroblast activation protein, a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts
description
1999 nî lūn-bûn
@nan
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Fibroblast activation protein, ...... uman tumor stromal fibroblasts
@ast
Fibroblast activation protein, ...... uman tumor stromal fibroblasts
@en
Fibroblast activation protein, ...... uman tumor stromal fibroblasts
@en-gb
Fibroblast activation protein, ...... uman tumor stromal fibroblasts
@nl
type
label
Fibroblast activation protein, ...... uman tumor stromal fibroblasts
@ast
Fibroblast activation protein, ...... uman tumor stromal fibroblasts
@en
Fibroblast activation protein, ...... uman tumor stromal fibroblasts
@en-gb
Fibroblast activation protein, ...... uman tumor stromal fibroblasts
@nl
prefLabel
Fibroblast activation protein, ...... uman tumor stromal fibroblasts
@ast
Fibroblast activation protein, ...... uman tumor stromal fibroblasts
@en
Fibroblast activation protein, ...... uman tumor stromal fibroblasts
@en-gb
Fibroblast activation protein, ...... uman tumor stromal fibroblasts
@nl
P2093
P2860
P921
P356
P1476
Fibroblast activation protein, ...... uman tumor stromal fibroblasts
@en
P2093
M C Lenter
P Garin-Chesa
R N Zimmermann
W J Rettig
P2860
P304
P356
10.1074/JBC.274.51.36505
P407
P577
1999-12-17T00:00:00Z