High Frequency of Cryptic Deleterious Mutations in Caenorhabditis elegans
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Distribution of fitness effects caused by single-nucleotide substitutions in bacteriophage f1The distribution of fitness effects of new deleterious amino acid mutations in humansMutational fitness effects in RNA and single-stranded DNA viruses: common patterns revealed by site-directed mutagenesis studiesBehavioral degradation under mutation accumulation in Caenorhabditis elegansMechanisms of genetic robustness in RNA virusesWhole-genome effects of ethyl methanesulfonate-induced mutation on nine quantitative traits in outbred Drosophila melanogasterDirect estimate of the mutation rate and the distribution of fitness effects in the yeast Saccharomyces cerevisiaeThe fitness effects of random mutations in single-stranded DNA and RNA bacteriophagesOn the potential for extinction by Muller's ratchet in Caenorhabditis elegansA framework for evolutionary systems biologyCumulative effects of spontaneous mutations for fitness in Caenorhabditis: role of genotype, environment and stressThe effect of induced mutations on quantitative traits in Arabidopsis thaliana: Natural versus artificial conditionsHigh-throughput isolation and mapping of C. elegans mutants susceptible to pathogen infection.Purging deleterious mutations under self fertilization: paradoxical recovery in fitness with increasing mutation rate in Caenorhabditis elegans.Experimental Evolution with Caenorhabditis Nematodes.Fitness is strongly influenced by rare mutations of large effect in a microbial mutation accumulation experiment.Estimation of spontaneous genome-wide mutation rate parameters: whither beneficial mutations?Mechanisms of molecular evolution.Genomic mutation rates: what high-throughput methods can tell usMicroevolutionary studies in nematodes: a beginning.Spontaneous mutational correlations for life-history, morphological and behavioral characters in Caenorhabditis elegansGenomic mutation in lines of Arabidopsis thaliana exposed to ultraviolet-B radiation.Multigeneration maximum-likelihood analysis applied to mutation-accumulation experiments in Caenorhabditis elegans.Spontaneous mutational effects on reproductive traits of arabidopsis thaliana.Estimates of the rate and distribution of fitness effects of spontaneous mutation in Saccharomyces cerevisiaeRegions of lower crossing over harbor more rare variants in African populations of Drosophila melanogaster.Dependence of epistasis on environment and mutation severity as revealed by in silico mutagenesis of phage t7.The anomalous effects of biased mutation.Mutation accumulation in populations of varying size: the distribution of mutational effects for fitness correlates in Caenorhabditis elegansEstimates of the genomic mutation rate for detrimental alleles in Drosophila melanogasterPleiotropic model of maintenance of quantitative genetic variation at mutation-selection balance.Epistasis correlates to genomic complexity.Low impact of germline transposition on the rate of mildly deleterious mutation in Caenorhabditis elegans.Approximation to the distribution of fitness effects across functional categories in human segregating polymorphisms.Accumulation of deleterious mutations in small abiotic populations of RNAExperimental estimate of the abundance and effects of nearly neutral mutations in the RNA virus phi 6.Effect of mutation mechanisms on variant composition and distribution in Caenorhabditis elegans.Accumulation of spontaneous mutations in the ciliate Tetrahymena thermophilaComparing mutational and standing genetic variability for fitness and size in Caenorhabditis briggsae and C. elegans.Rate and effects of spontaneous mutations that affect fitness in mutator Escherichia coli.
P2860
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P2860
High Frequency of Cryptic Deleterious Mutations in Caenorhabditis elegans
description
1999 nî lūn-bûn
@nan
1999 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
High Frequency of Cryptic Deleterious Mutations in Caenorhabditis elegans
@ast
High Frequency of Cryptic Deleterious Mutations in Caenorhabditis elegans
@en
High Frequency of Cryptic Deleterious Mutations in Caenorhabditis elegans
@en-gb
type
label
High Frequency of Cryptic Deleterious Mutations in Caenorhabditis elegans
@ast
High Frequency of Cryptic Deleterious Mutations in Caenorhabditis elegans
@en
High Frequency of Cryptic Deleterious Mutations in Caenorhabditis elegans
@en-gb
altLabel
High frequency of cryptic deleterious mutations in Caenorhabditis elegans.
@ast
High frequency of cryptic deleterious mutations in Caenorhabditis elegans.
@en
prefLabel
High Frequency of Cryptic Deleterious Mutations in Caenorhabditis elegans
@ast
High Frequency of Cryptic Deleterious Mutations in Caenorhabditis elegans
@en
High Frequency of Cryptic Deleterious Mutations in Caenorhabditis elegans
@en-gb
P2093
P1433
P1476
High Frequency of Cryptic Deleterious Mutations in Caenorhabditis elegans
@en
High frequency of cryptic deleterious mutations in Caenorhabditis elegans.
@en
P2093
E. K. Davies
Keightley PD
P304
P356
10.1126/SCIENCE.285.5434.1748
P407
P577
1999-09-01T00:00:00Z
1999-09-10T00:00:00Z