sameAs
P2176
P3781
NVP-LDE225, a potent and selective SMOOTHENED antagonist reduces melanoma growth in vitro and in vivoAn Investigator-Initiated Open-Label Trial of Sonidegib in Advanced Basal Cell Carcinoma Patients Resistant to VismodegibProteasome inhibition reverses hedgehog inhibitor and taxane resistance in ovarian cancer.Inhibition of Hedgehog signalling by NVP-LDE225 (Erismodegib) interferes with growth and invasion of human renal cell carcinoma cellsThe Hedgehog pathway as targetable vulnerability with 5-azacytidine in myelodysplastic syndrome and acute myeloid leukemiaTumor-Priming Smoothened Inhibitor Enhances Deposition and Efficacy of Cytotoxic Nanoparticles in a Pancreatic Cancer ModelNPV-LDE-225 (Erismodegib) inhibits epithelial mesenchymal transition and self-renewal of glioblastoma initiating cells by regulating miR-21, miR-128, and miR-200Treatment with two different doses of sonidegib in patients with locally advanced or metastatic basal cell carcinoma (BOLT): a multicentre, randomised, double-blind phase 2 trial.Hedgehog Inhibitors in Rhabdomyosarcoma: A Comparison of Four Compounds and Responsiveness of Four Cell Lines.A five-gene hedgehog signature developed as a patient preselection tool for hedgehog inhibitor therapy in medulloblastoma.A phase I, multicenter, open-label, first-in-human, dose-escalation study of the oral smoothened inhibitor Sonidegib (LDE225) in patients with advanced solid tumors.Absorption, distribution, metabolism, and excretion (ADME) of ¹⁴C-sonidegib (LDE225) in healthy volunteers.Hedgehog Signaling Regulates Taste Organs and Oral Sensation: Distinctive Roles in the Epithelium, Stroma, and Innervation
P921
Q21132689-6F27429B-3B91-4E5A-A393-2A7D98473B69Q27853239-ED7F1061-439A-4A6D-9A67-6F85BF222F56Q30410019-7C7BEE8F-E58B-4878-84FD-8AC42E74AA65Q35678417-A518CF2A-273D-4B28-A00C-F674B8ACA242Q36190177-32544969-1C99-47CF-8805-C832D13BA37AQ36447756-20926E9D-7380-4FDB-BE81-131FB88D491CQ36866011-D68F3E52-C763-4C43-A616-0336A805A1CBQ38485521-B694C2BE-0C41-443C-8DBD-ABE5973225AAQ40803127-765AD38B-3118-48BE-AE03-0FF5CB8ABD6AQ41729473-CE6D045F-0523-4211-A615-3A2D480F913CQ42454105-C43F2EC1-10EB-4BBB-BEA0-C90FB43AEF2AQ42705701-7E687C6D-65F7-474A-B2E6-7018879036A7Q64084362-A967E59F-C1E7-4159-B02B-DDA92D3A1B53
P921
description
chemesch Verbindung
@lb
chemical compound
@en
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de
chemische Verbindung
@de-ch
chemische verbinding
@nl
name
Sonidegib
@vi
sonidegib
@en
سونيديغيب
@ar
type
label
Sonidegib
@vi
sonidegib
@en
سونيديغيب
@ar
altLabel
Erismodegib
@en
LDE 225
@en
LDE-225
@en
LDE225
@en
N-[6-(cis-2,6-dimethylmorpholi ...... )[1,1'-biphenyl]-3-carboxamide
@en
NVP-LDE 225
@en
NVP-LDE225
@en
Odomzo®
@en
Sonidegib
@en
erismodegib (deleted INN)
@en
prefLabel
Sonidegib
@vi
sonidegib
@en
سونيديغيب
@ar
P592
P6366
P661
P662
P665
P683
P1579
P2017
C[C@@H]1CN(C[C@@H](O1)C)C2=NC=C(C=C2)NC(=O)C3=CC=CC(=C3C)C4=CC=C(C=C4)OC(F)(F)F
P2067
485.192626
P2115
N0000192023
P2175
P2275
sonidegib
@en
P231
956697-53-3
P233
CC1CN(CC(O1)C)C2=NC=C(C=C2)NC(=O)C3=CC=CC(=C3C)C4=CC=C(C=C4)OC(F)(F)F