The Role of Molecular Imaging in Drug Discovery and Development
about
Occupancy of dopamine D₂ and D₃ and serotonin 5-HT₁A receptors by the novel antipsychotic drug candidate, cariprazine (RGH-188), in monkey brain measured using positron emission tomographyDevelopment of New Deoxycytidine Kinase Inhibitors and Noninvasive in Vivo Evaluation Using Positron Emission TomographyInvestigation of cross-species translatability of pharmacological MRI in awake nonhuman primate - a buprenorphine challenge studyPredictive and prognostic molecular markers for cancer medicineGuidance for Efficient Small Animal Imaging Quality ControlLigand conjugation to bimodal poly(ethylene glycol) brush layers on microbubbles.Opening up the optical imaging window using nano-luciferin.Can Functional Magnetic Resonance Imaging Improve Success Rates in CNS Drug Discovery?Specific biomarkers of receptors, pathways of inhibition and targeted therapies: clinical applications.Essential parameters to consider for the characterization of optical imaging probes.Use of DNA microarray and small animal positron emission tomography in preclinical drug evaluation of RAF265, a novel B-Raf/VEGFR-2 inhibitor.Quantitative in vivo immunohistochemistry of epidermal growth factor receptor using a receptor concentration imaging approachLost but making progress--Where will new analgesic drugs come from?Molecular imaging in tumor angiogenesis and relevant drug researchA modular labeling strategy for in vivo PET and near-infrared fluorescence imaging of nanoparticle tumor targetingMolecular Imaging of Membrane Transporters' Activity in Cancer: a Picture is Worth a Thousand Tubes.Rational chemical design of the next generation of molecular imaging probes based on physics and biology: mixing modalities, colors and signalsThe evolving role of nuclear molecular imaging in cancer.Synthesis, radiosynthesis, and biological evaluation of fluorine-18-labeled 2beta-carbo(fluoroalkoxy)-3beta-(3'-((Z)-2-haloethenyl)phenyl)nortropanes: candidate radioligands for in vivo imaging of the serotonin transporter with positron emission tomA review of imaging agent development.Impact of a multiple mice holder on quantitation of high-throughput MicroPET imaging with and without Ct attenuation correction.Fluorine-18 Radiolabeled PET Tracers for Imaging Monoamine Transporters: Dopamine, Serotonin, and Norepinephrine.New ultrasensitive detection technologies and techniques for use in microdosing studies.The proteomic toolbox for studying cerebrospinal fluid.Optimizing Central Nervous System Drug Development Using Molecular Imaging.Considerations in the Development of Reversibly Binding PET Radioligands for Brain Imaging.The development of biomarkers to reduce attrition rate in drug discovery focused on oncology and central nervous system.Near-Infrared Fluorescent Nanoprobes for in Vivo Optical Imaging.MRI Contrast Agents for Pharmacological Research.A New Highly Reactive and Low Lipophilicity Fluorine-18 Labeled Tetrazine Derivative for Pretargeted PET Imaging.Production of diverse PET probes with limited resources: 24 18F-labeled compounds prepared with a single radiosynthesizer.Imaging as a tumor biomarker in oncology drug trials for lung cancer: the FDA perspective.Advancing Drug Discovery and Development Using Molecular Imaging (ADDMI): an Interest Group of the World Molecular Imaging Society and an Inaugural Session on Positron Emission Tomography (PET).Advances in antiviral drug discovery and development: Part II: Advancements in antiviral drug developmentIdentifying needs and opportunities for advancing translational research in cardiovascular disease
P2860
Q24630426-BB83C745-2330-494C-8884-58CFABDC4D29Q27679693-870F84ED-2FAA-444B-A32E-2A4CB714E8E8Q28543992-BA8801F1-66ED-4C27-9252-047F1603A5AEQ28743108-6F53086E-44BD-4A4E-91CB-78577159496FQ30275741-6274AD26-4EEC-448B-BD5F-CE63B7EC9E79Q30474502-02F806E4-13E0-4A33-A4EF-FD6B7DCD6234Q30596619-900B97AB-530A-4CE4-B3E1-5EAAB2803BB0Q33963735-CED476A6-BCEA-46FD-87D9-4AAD5E31A13AQ34203953-BE02FFDE-164D-4BB7-B2AD-C3F226785696Q34356559-7D090553-0A75-4E23-9E48-7065851E6C21Q34633685-626EF917-9E16-423D-AF92-0E328B934B78Q34717908-486E9841-A371-48DF-93A5-4C92DCFD78C1Q35058471-51087F25-A51E-4F72-97FD-B2BA0407EFF7Q35130907-12597FEE-7200-4914-B7C2-CEDA24E6007FQ35238675-4AB70E0B-FF69-4026-855E-E51CE00D2E7FQ35768413-5C6AA4EC-8797-4649-A555-679DAE45F4C5Q36158324-2DCB7F12-3211-4E02-BE4F-0D629DBF02F7Q37011086-7A64BEA7-4484-4085-81D8-9B022B56065DQ37156598-04B274F1-166E-47C1-A866-ACA1F64D8C96Q37214528-5429AC02-5990-4A85-9512-A45E876F630FQ37594758-6D7969E4-7F47-421E-B612-BE1EB924F9E2Q37706110-C1EDCB2A-43EC-485E-A643-D83EDACE5C96Q37810198-0AD8A631-126F-4E87-9F9E-63BCD1780698Q37998531-C219509D-E956-402F-A442-7DF48A29D6A6Q38419418-53A7F300-EB5C-4FCD-AF5A-0DD79257822AQ38810544-B169A8C4-FE9E-4DF8-A373-4720E093C253Q38907580-42F0C32F-09DE-4A33-B63C-04230A9C9030Q39203551-52EBE8DC-4A85-4F0B-8082-873F92C414F5Q42084719-E3EFAE30-34E2-47EE-8248-F03006DD79B3Q43083925-1B184896-A4EE-4B01-A770-ED974675022CQ46092721-34D0CE7F-659E-476C-AC15-03C092652DC5Q47389774-518BD298-7062-4ACD-96E4-FFBD7C6E1B5FQ48267766-C8D6CDF7-1A37-458C-A8DF-EE8693FB6F7EQ56749631-AD2B08D8-339E-4F36-ADF9-182BD62A2B22Q56986575-D71B7A5D-BBDB-4EF7-9173-930F57E1C311
P2860
The Role of Molecular Imaging in Drug Discovery and Development
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The Role of Molecular Imaging in Drug Discovery and Development
@ast
The Role of Molecular Imaging in Drug Discovery and Development
@en
The Role of Molecular Imaging in Drug Discovery and Development
@en-gb
The Role of Molecular Imaging in Drug Discovery and Development
@nl
type
label
The Role of Molecular Imaging in Drug Discovery and Development
@ast
The Role of Molecular Imaging in Drug Discovery and Development
@en
The Role of Molecular Imaging in Drug Discovery and Development
@en-gb
The Role of Molecular Imaging in Drug Discovery and Development
@nl
altLabel
The role of molecular imaging in drug discovery and development
@en
prefLabel
The Role of Molecular Imaging in Drug Discovery and Development
@ast
The Role of Molecular Imaging in Drug Discovery and Development
@en
The Role of Molecular Imaging in Drug Discovery and Development
@en-gb
The Role of Molecular Imaging in Drug Discovery and Development
@nl
P356
P1476
The Role of Molecular Imaging in Drug Discovery and Development
@en
P2093
RJ Hargreaves
P304
P356
10.1038/SJ.CLPT.6100467
P407
P577
2008-01-02T00:00:00Z