Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice
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Molecular topology as novel strategy for discovery of drugs with aβ lowering and anti-aggregation dual activities for Alzheimer's diseasePersistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer diseaseBiofilms formed by the archaeon Haloferax volcanii exhibit cellular differentiation and social motility, and facilitate horizontal gene transfer.S100A7, a novel Alzheimer's disease biomarker with non-amyloidogenic alpha-secretase activity acts via selective promotion of ADAM-10In vivo imaging reveals sigmoidal growth kinetic of β-amyloid plaques.Clinical immunologic approaches for the treatment of Alzheimer's diseaseCurrent Insights into Molecular Mechanisms of Alzheimer Disease and Their Implications for Therapeutic ApproachesBehavioral alterations associated with apoptosis and down-regulation of presenilin 1 in the brains of p53-deficient miceActin-binding proteins coronin-1a and IBA-1 are effective microglial markers for immunohistochemistryGene transfer of human Apoe isoforms results in differential modulation of amyloid deposition and neurotoxicity in mouse brainBRI2 (ITM2b) inhibits Abeta deposition in vivoGGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β productionContribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic miceNasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears beta-amyloid in a mouse model of Alzheimer diseaseDissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's diseaseClearance of amyloid-beta by circulating lipoprotein receptorsProtein phosphatase 5 protects neurons against amyloid-beta toxicityAbeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse modelsMolecular cross talk between misfolded proteins in animal models of Alzheimer's and prion diseasesDown-regulation of DENN/MADD, a TNF receptor binding protein, correlates with neuronal cell death in Alzheimer's disease brain and hippocampal neuronsAcceleration of brain amyloidosis in an Alzheimer's disease mouse model by a folate, vitamin B6 and B12-deficient dietAmyloid-beta dynamics are regulated by orexin and the sleep-wake cycleReversal of long-term dendritic spine alterations in Alzheimer disease modelsLeptin regulates tau phosphorylation and amyloid through AMPK in neuronal cellsEffects of grape seed-derived polyphenols on amyloid beta-protein self-assembly and cytotoxicityActive and passive immunotherapy for neurodegenerative disordersValsartan lowers brain beta-amyloid protein levels and improves spatial learning in a mouse model of Alzheimer diseaseNSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivoIdentification of septins in neurofibrillary tangles in Alzheimer's diseasePin1 in Alzheimer's disease: multiple substrates, one regulatory mechanism?Brain inflammation and oxidative stress in a transgenic mouse model of Alzheimer-like brain amyloidosisUsing animal models to determine the significance of complement activation in Alzheimer's diseaseModelling neuroinflammatory phenotypes in vivoTransgenic nonhuman primates for neurodegenerative diseasesOvercoming antigen masking of anti-amyloidbeta antibodies reveals breaking of B cell tolerance by virus-like particles in amyloidbeta immunized amyloid precursor protein transgenic miceDysregulation of Na+/K+ ATPase by amyloid in APP+PS1 transgenic miceFocal glial activation coincides with increased BACE1 activation and precedes amyloid plaque deposition in APP[V717I] transgenic mice.Novel Abeta peptide immunogens modulate plaque pathology and inflammation in a murine model of Alzheimer's disease.Synapses and Alzheimer's disease
P2860
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P2860
Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice
description
1996 nî lūn-bûn
@nan
1996 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice
@ast
Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice
@en
Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice
@en-gb
type
label
Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice
@ast
Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice
@en
Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice
@en-gb
altLabel
Correlative Memory Deficits, A Elevation, and Amyloid Plaques in Transgenic Mice
@en
Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
@en
prefLabel
Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice
@ast
Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice
@en
Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice
@en-gb
P2093
P2860
P3181
P1433
P1476
Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice
@en
P2093
P. Chapman
S. Younkin
Y. Harigaya
P2860
P3181
P356
10.1126/SCIENCE.274.5284.99
P407
P577
1996-10-04T00:00:00Z