Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine - Wikidata - wikimedia - TriplyDB

Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine

Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine

http://www.wikidata.org/entity/Q22248084

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The dopamine β-hydroxylase -1021C/T polymorphism is associated with the risk of Alzheimer's disease in the Epistasis Project NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice Neuroimmune Interaction in the Regulation of Peripheral Opioid-Mediated Analgesia in Inflammation Role of Glia in Stress-Induced Enhancement and Impairment of Memory Role of pro-inflammatory cytokines released from microglia in Alzheimer's disease Rodent models of neuroinflammation for Alzheimer's disease Turning on the Light Within: Subcortical Nuclei of the Isodentritic Core and their Role in Alzheimer's Disease Pathogenesis Microglia development and function Monoaminergic and Histaminergic Strategies and Treatments in Brain Diseases Uncovering the Molecular Mechanism of Actions between Pharmaceuticals and Proteins on the AD Network The role of orphanin FQ/nociceptin in neuroplasticity: relationship to stress, anxiety and neuroinflammation.Norepinephrine modulates the motility of resting and activated microglia via different adrenergic receptors.In vivo dynamics of innate immune sentinels in the CNS.Amyloid β production is regulated by β2-adrenergic signaling-mediated post-translational modifications of the ryanodine receptor.Investigating Focal Connectivity Deficits in Alzheimer's Disease Using Directional Brain Networks Derived from Resting-State fMRI.Ear2 deletion causes early memory and learning deficits in APP/PS1 mice.Norepinephrine: a neuromodulator that boosts the function of multiple cell types to optimize CNS performance Microglial phenotype and adaptation.PSAPP mice exhibit regionally selective reductions in gliosis and plaque deposition in response to S100B ablation.Noradrenergic regulation of glial activation: molecular mechanisms and therapeutic implications.The catecholamine biosynthetic enzyme dopamine β-hydroxylase (DBH): first genome-wide search positions trait-determining variants acting additively in the proximal promoter.CD36 upregulation mediated by intranasal LV-NRF2 treatment mitigates hypoxia-induced progression of Alzheimer's-like pathogenesis.Slowing down: age-related neurobiological predictors of processing speed.Amyloid beta peptide-(1-42) induces internalization and degradation of beta2 adrenergic receptors in prefrontal cortical neurons Insulin improves memory and reduces chronic neuroinflammation in the hippocampus of young but not aged brains A novel role of microglial NADPH oxidase in mediating extra-synaptic function of norepinephrine in regulating brain immune homeostasis.Noradrenergic dysfunction in Alzheimer's disease.Age-related neurodegeneration and memory loss in down syndrome.Reduced tissue levels of noradrenaline are associated with behavioral phenotypes of the TgCRND8 mouse model of Alzheimer's disease.Noninvasive molecular imaging of neuroinflammation Exendin-4 protected against cognitive dysfunction in hyperglycemic mice receiving an intrahippocampal lipopolysaccharide injection.The association of neuropsychiatric symptoms in MCI with incident dementia and Alzheimer disease.Soluble beta amyloid evokes alteration in brain norepinephrine levels: role of nitric oxide and interleukin-1.Quercitrin for periodontal regeneration: effects on human gingival fibroblasts and mesenchymal stem cells.Norepinephrine Protects against Amyloid-β Toxicity via TrkB.The Locus Coeruleus: Essential for Maintaining Cognitive Function and the Aging Brain.The noradrenaline precursor L-DOPS reduces pathology in a mouse model of Alzheimer's disease Differential relationships of reactive astrocytes and microglia to fibrillar amyloid deposits in Alzheimer disease.Targeting norepinephrine in mild cognitive impairment and Alzheimer's disease.Pathways to neurodegeneration: mechanistic insights from GWAS in Alzheimer's disease, Parkinson's disease, and related disorders

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Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine

http://www.wikidata.org/entity/Q22248084

description

2010 nî lūn-bûn

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2010 թուականի Մարտին հրատարակուած գիտական յօդուած

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2010 թվականի մարտին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Locus ceruleus controls Alzhei ...... nctions through norepinephrine

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Locus ceruleus controls Alzhei ...... nctions through norepinephrine

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Locus ceruleus controls Alzhei ...... nctions through norepinephrine

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type

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Locus ceruleus controls Alzhei ...... nctions through norepinephrine

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Locus ceruleus controls Alzhei ...... nctions through norepinephrine

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Locus ceruleus controls Alzhei ...... nctions through norepinephrine

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Locus ceruleus controls Alzhei ...... nctions through norepinephrine

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Locus ceruleus controls Alzhei ...... nctions through norepinephrine

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Locus ceruleus controls Alzhei ...... nctions through norepinephrine

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Proceedings of the National Academy of Sciences of the United States of America

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Locus ceruleus controls Alzhei ...... nctions through norepinephrine

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Ana Martinez-Hernandez

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Daniel Jardanhazi-Kurutz

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Dick Terwel

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Fabian Nadrigny

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Jochen Walter

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Lucia Dumitrescu-Ozimek

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Michael T Heneka

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Tommy Regen

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P2860

ScanImage: flexible software for operating laser scanning microscopes.

Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain

Patterns of cerebrospinal fluid catechols support increased central noradrenergic responsiveness in aging and Alzheimer's disease

A distinct role for norepinephrine in memory retrieval

Restoration of norepinephrine and reversal of phenotypes in mice lacking dopamine beta-hydroxylase

Microglia: active sensor and versatile effector cells in the normal and pathologic brain

Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion

Current concepts in mild cognitive impairment.

Locus ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice.

Noradrenergic regulation of inflammatory gene expression in brain.

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Markus P Kummer

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41969128

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20231476

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Alzheimer's disease

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