Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein
about
Prediction of protein binding regions in disordered proteinsThe WASP and WAVE family proteinsClassification of intrinsically disordered regions and proteinsIntegrative annotation of variants from 1092 humans: application to cancer genomicsScar/WAVE-1, a Wiskott-Aldrich syndrome protein, assembles an actin-associated multi-kinase scaffoldA new family of Cdc42 effector proteins, CEPs, function in fibroblast and epithelial cell shape changesBorg proteins control septin organization and are negatively regulated by Cdc42Phosphorylation of WASP by the Cdc42-associated kinase ACK1: dual hydroxyamino acid specificity in a tyrosine kinaseErk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASPProtein-tyrosine kinase and GTPase signals cooperate to phosphorylate and activate Wiskott-Aldrich syndrome protein (WASP)/neuronal WASPStructure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6A Dictyostelium homologue of WASP is required for polarized F-actin assembly during chemotaxisIdentification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO1A hydrophobic pocket in the active site of glycolytic aldolase mediates interactions with Wiskott-Aldrich syndrome proteinWASH and the Arp2/3 complex regulate endosome shape and trafficking.Phosphorylation of tyrosine 291 enhances the ability of WASp to stimulate actin polymerization and filopodium formation. Wiskott-Aldrich Syndrome proteinStructure and control of the actin regulatory WAVE complexWHAMM is an Arp2/3 complex activator that binds microtubules and functions in ER to Golgi transportWiskott-Aldrich syndrome protein is involved in alphaIIb beta3-mediated cell adhesionSorting nexin 33 induces mammalian cell micronucleated phenotype and actin polymerization by interacting with Wiskott-Aldrich syndrome proteinConstitutive activated Cdc42-associated kinase (Ack) phosphorylation at arrested endocytic clathrin-coated pits of cells that lack dynaminRegulation of WASH-dependent actin polymerization and protein trafficking by ubiquitinationA WASp-VASP complex regulates actin polymerization at the plasma membrane.Motility determinants in WASP family proteins.Nir2, a novel regulator of cell morphogenesisActin-based motility of intracellular microbial pathogensLoss of WAVE-1 causes sensorimotor retardation and reduced learning and memory in mice.Involvement of the Arp2/3 complex and Scar2 in Golgi polarity in scratch wound modelsTargeted wild-type and jerker espins reveal a novel, WH2-domain-dependent way to make actin bundles in cellsA novel phospholipase D2-Grb2-WASp heterotrimer regulates leukocyte phagocytosis in a two-step mechanismWASP family proteins: their evolution and its physiological implications.Regulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contextsAutoinhibition regulates cellular localization and actin assembly activity of the diaphanous-related formins FRLalpha and mDia1.Molecular and Cellular Mechanisms of Shigella flexneri Dissemination.Control of Dendritic Spine Morphological and Functional Plasticity by Small GTPasesSynthetic Protein Scaffolds Based on Peptide Motifs and Cognate Adaptor Domains for Improving Metabolic ProductivityInsights into rapid modulation of neuroplasticity by brain estrogensUnder lock and key: spatiotemporal regulation of WASP family proteins coordinates separate dynamic cellular processesRab1 recruits WHAMM during membrane remodeling but limits actin nucleation.Molecular difference between WASP and N-WASP critical for chemotaxis of T-cells towards SDF-1α.
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P2860
Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein
description
2000 nî lūn-bûn
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2000 թուականի Մարտին հրատարակուած գիտական յօդուած
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2000 թվականի մարտին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
@zh-tw
2000年论文
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name
Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein
@ast
Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein
@en
Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein
@en-gb
Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein
@nl
type
label
Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein
@ast
Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein
@en
Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein
@en-gb
Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein
@nl
prefLabel
Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein
@ast
Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein
@en
Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein
@en-gb
Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein
@nl
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Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein
@en
P2093
P2888
P3181
P356
10.1038/35004513
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P577
2000-03-09T00:00:00Z
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P6179
1045390976