The B56alpha regulatory subunit of protein phosphatase 2A is a target for regulation by double-stranded RNA-dependent protein kinase PKR
about
The role of PACT in the RNA silencing pathwayB56-containing PP2A dephosphorylate ERK and their activity is controlled by the early gene IEX-1 and ERKProtein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signallingAmino acids as regulators of gene expressionProtein Phosphatase 2A as a Therapeutic Target in Acute Myeloid LeukemiaAmino acid sensing in dietary-restriction-mediated longevity: roles of signal-transducing kinases GCN2 and TORLocalization of Saccharomyces cerevisiae protein phosphatase 2A subunits throughout mitotic cell cycle.The direct binding of the catalytic subunit of protein phosphatase 1 to the PKR protein kinase is necessary but not sufficient for inactivation and disruption of enzyme dimer formationmTOR/p70S6k signalling alteration by Abeta exposure as well as in APP-PS1 transgenic models and in patients with Alzheimer's diseaseA genome-scale RNA-interference screen identifies RRAS signaling as a pathologic feature of Huntington's diseaseMolecular basis for PP2A regulatory subunit B56alpha targeting in cardiomyocytesThe protein phosphatase 2A regulatory subunits B'beta and B'delta mediate sustained TrkA neurotrophin receptor autophosphorylation and neuronal differentiationRespiratory syncytial virus limits alpha subunit of eukaryotic translation initiation factor 2 (eIF2alpha) phosphorylation to maintain translation and viral replicationA dynamic analysis of IRS-PKR signaling in liver cells: a discrete modeling approach.Inhibition of protein synthesis in cortical neurons during exposure to hydrogen peroxide.Protein kinase RNA/FADD/caspase-8 pathway mediates the proapoptotic activity of the RNA-binding protein human antigen R (HuR).The double-stranded RNA-dependent protein kinase differentially regulates insulin receptor substrates 1 and 2 in HepG2 cellsTranslational regulation in cell stress and apoptosis. Roles of the eIF4E binding proteins.Double-stranded RNA-dependent protein kinase phosphorylation of the alpha-subunit of eukaryotic translation initiation factor 2 mediates apoptosis.Molecular mechanism by which palmitate inhibits PKR autophosphorylation.Protein kinase regulated by dsRNA downregulates the interferon production in dengue virus- and dsRNA-stimulated human lung epithelial cellsAlphavirus-based DNA vaccine breaks immunological tolerance by activating innate antiviral pathwaysControlling activation of the RNA-dependent protein kinase by siRNAs using site-specific chemical modificationExpression of PACT is regulated by Sp1 transcription factor.A Three Stage Integrative Pathway Search (TIPS) framework to identify toxicity relevant genes and pathways.PKR inhibits the DNA damage response, and is associated with poor survival in AML and accelerated leukemia in NHD13 mice.RNA-dependent protein kinase PKR and the Z-DNA binding orthologue PKZ differ in their capacity to mediate initiation factor eIF2α-dependent inhibition of protein synthesis and virus-induced stress granule formation.PKR regulates B56(alpha)-mediated BCL2 phosphatase activity in acute lymphoblastic leukemia-derived REH cellsRepression of PKR mediates palmitate-induced apoptosis in HepG2 cells through regulation of Bcl-2.Protein kinase PKR-dependent activation of mitogen-activated protein kinases occurs through mitochondrial adapter IPS-1 and is antagonized by vaccinia virus E3L.PKR, the double stranded RNA-dependent protein kinase as a critical target in Alzheimer's diseaseSuppression of protein phosphatase 2 differentially modulates VEGF- and FGF2-induced signaling in ovine fetoplacental artery endothelial cellsProtein phosphatase 2A is regulated by protein kinase Cα (PKCα)-dependent phosphorylation of its targeting subunit B56α at Ser41.Sustained Action of Ceramide on the Insulin Signaling Pathway in Muscle Cells: IMPLICATION OF THE DOUBLE-STRANDED RNA-ACTIVATED PROTEIN KINASEPP2A as a master regulator of the cell cycle.Roles of PKR in differentiation and apoptosis of bone-related cells.Protein Phosphatase 2A: a Double-Faced Phosphatase of Cellular System and Its Role in Neurodegenerative Disorders.Apoptosis induced by the kinase inhibitor BAY 43-9006 in human leukemia cells involves down-regulation of Mcl-1 through inhibition of translation.Involvement of the interferon-regulated antiviral proteins PKR and RNase L in reovirus-induced shutoff of cellular translation.Double stranded RNA-dependent protein kinase promotes the tumorigenic phenotype in HepG2 hepatocellular carcinoma cells by activating STAT3.
P2860
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P2860
The B56alpha regulatory subunit of protein phosphatase 2A is a target for regulation by double-stranded RNA-dependent protein kinase PKR
description
2000 nî lūn-bûn
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2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
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2000年论文
@wuu
name
The B56alpha regulatory subuni ...... A-dependent protein kinase PKR
@ast
The B56alpha regulatory subuni ...... A-dependent protein kinase PKR
@en
The B56alpha regulatory subuni ...... A-dependent protein kinase PKR
@en-gb
The B56alpha regulatory subuni ...... A-dependent protein kinase PKR
@nl
type
label
The B56alpha regulatory subuni ...... A-dependent protein kinase PKR
@ast
The B56alpha regulatory subuni ...... A-dependent protein kinase PKR
@en
The B56alpha regulatory subuni ...... A-dependent protein kinase PKR
@en-gb
The B56alpha regulatory subuni ...... A-dependent protein kinase PKR
@nl
prefLabel
The B56alpha regulatory subuni ...... A-dependent protein kinase PKR
@ast
The B56alpha regulatory subuni ...... A-dependent protein kinase PKR
@en
The B56alpha regulatory subuni ...... A-dependent protein kinase PKR
@en-gb
The B56alpha regulatory subuni ...... A-dependent protein kinase PKR
@nl
P2860
P3181
P1476
The B56alpha regulatory subuni ...... A-dependent protein kinase PKR
@en
P2860
P304
P3181
P356
10.1128/MCB.20.14.5285-5299.2000
P407
P577
2000-07-01T00:00:00Z