Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement
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Analysis of mitotic phosphorylation of borealinMolecular analysis of survivin isoforms: evidence that alternatively spliced variants do not play a role in mitosisAcetylation directs survivin nuclear localization to repress STAT3 oncogenic activityHBXIP functions as a cofactor of survivin in apoptosis suppressionThreonine 48 in the BIR domain of survivin is critical to its mitotic and anti-apoptotic activities and can be phosphorylated by CK2 in vitroThe Schizosaccharomyces pombe aurora-related kinase Ark1 interacts with the inner centromere protein Pic1 and mediates chromosome segregation and cytokinesis.Uncoupling the central spindle-associated function of the chromosomal passenger complex from its role at centromeresCentromere targeting of the chromosomal passenger complex requires a ternary subcomplex of Borealin, Survivin, and the N-terminal domain of INCENPSurvivin - The inconvenient IAPThe mitotic regulator Survivin binds as a monomer to its functional interactor BorealinStructure-Based Design, Synthesis, Evaluation, and Crystallographic Studies of Conformationally Constrained Smac Mimetics as Inhibitors of the X-linked Inhibitor of Apoptosis Protein (XIAP) †Structural Basis for Recognition of H3T3ph and Smac/DIABLO N-terminal Peptides by Human SurvivinDirect interaction between survivin and Smac/DIABLO is essential for the anti-apoptotic activity of survivin during taxol-induced apoptosisSurvivin enhances Aurora-B kinase activity and localizes Aurora-B in human cellsCancer gene therapy using a survivin mutant adenovirusPerformance of survivin mRNA as a biomarker for bladder cancer in the prospective study UroScreenThe tumor gene survivin is highly expressed in adult renal tubular cells: implications for a pathophysiological role in the kidneyThreonine-4 of mammalian RNA polymerase II CTD is targeted by Polo-like kinase 3 and required for transcriptional elongationAurora B kinase exists in a complex with survivin and INCENP and its kinase activity is stimulated by survivin binding and phosphorylation.Deconstructing Survivin: comprehensive genetic analysis of Survivin function by conditional knockout in a vertebrate cell line.Survivin antisense compound inhibits proliferation and promotes apoptosis in liver cancer cells.Localization, dynamics, and function of survivin revealed by expression of functional survivinDsRed fusion proteins in the living cell.Survivin, a molecular target for therapeutic interventions in squamous cell carcinoma.Differential regulation of survivin expression and apoptosis by vitamin D3 compounds in two isogenic MCF-7 breast cancer cell sublinesRegulation of survivin function by Hsp90Survivin expression pattern in the intestine of normoxic and ischemic rats.The antiapoptotic gene survivin is highly expressed in human chondrosarcoma and promotes drug resistance in chondrosarcoma cells in vitro.Cleavage of survivin by Granzyme M triggers degradation of the survivin-X-linked inhibitor of apoptosis protein (XIAP) complex to free caspase activity leading to cytolysis of target tumor cellsWNT1-inducible signaling pathway protein-1 activates diverse cell survival pathways and blocks doxorubicin-induced cardiomyocyte deathA role for survivin in chemoresistance of endothelial cells mediated by VEGFCharacterization of an anti-apoptotic glycoprotein encoded by Kaposi's sarcoma-associated herpesvirus which resembles a spliced variant of human survivin.Suppressors of Bir1p (Survivin) identify roles for the chromosomal passenger protein Pic1p (INCENP) and the replication initiation factor Psf2p in chromosome segregation.A cell-permeable dominant-negative survivin protein induces apoptosis and sensitizes prostate cancer cells to TNF-α therapy.Impacting tumor cell-fate by targeting the inhibitor of apoptosis protein survivinCompetitive inhibition of survivin using a cell-permeable recombinant protein induces cancer-specific apoptosis in colon cancer model.Survivin an important determinant for prognosis in adult T-cell leukemia: a novel biomarker in practical hemato-oncology.Casein kinase 2 (CK2) increases survivin expression via enhanced beta-catenin-T cell factor/lymphoid enhancer binding factor-dependent transcriptionCell death in response to antimetabolites directed at ribonucleotide reductase and thymidylate synthaseUpregulation of survivin in G2/M cells and inhibition of caspase 9 activity enhances resistance in staurosporine-induced apoptosis.Survivin and IAP proteins in cell-death mechanisms
P2860
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P2860
Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement
description
2000 nî lūn-bûn
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2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
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2000 թվականի հուլիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
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name
Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement
@ast
Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement
@en
Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement
@en-gb
Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement
@nl
type
label
Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement
@ast
Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement
@en
Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement
@en-gb
Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement
@nl
prefLabel
Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement
@ast
Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement
@en
Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement
@en-gb
Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement
@nl
P2093
P921
P3181
P356
P1476
Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement
@en
P2093
P3181
P356
10.1038/76838
P407
P577
2000-07-01T00:00:00Z