about
NCLX is an essential component of mitochondrial Na+/Ca2+ exchangeModafinil alters intrinsic functional connectivity of the right posterior insula: a pharmacological resting state fMRI studyThe mitochondrial Na+/Ca2+ exchanger upregulates glucose dependent Ca2+ signalling linked to insulin secretionBrain monoglyceride lipase participating in endocannabinoid inactivationAcute effects of modafinil on brain resting state networks in young healthy subjectsAltered Kv2.1 functioning promotes increased excitability in hippocampal neurons of an Alzheimer's disease mouse model.Microarray analysis on human neuroblastoma cells exposed to aluminum, β(1-42)-amyloid or the β(1-42)-amyloid aluminum complex.Alterations of brain and cerebellar proteomes linked to Aβ and tau pathology in a female triple-transgenic murine model of Alzheimer's disease.Effects of dietary supplementation of carnosine on mitochondrial dysfunction, amyloid pathology, and cognitive deficits in 3xTg-AD mice.Age-Dependent Modifications of AMPA Receptor Subunit Expression Levels and Related Cognitive Effects in 3xTg-AD Mice.Zn(2+): a novel ionic mediator of neural injury in brain disease.Effects of non-pharmacological or pharmacological interventions on cognition and brain plasticity of aging individuals.Dietary zinc supplementation of 3xTg-AD mice increases BDNF levels and prevents cognitive deficits as well as mitochondrial dysfunctionModulation of mitochondrial function by endogenous Zn2+ pools.The neurophysiology and pathology of brain zinc.Rethinking the excitotoxic ionic milieu: the emerging role of Zn(2+) in ischemic neuronal injury.Left hippocampus-amygdala complex macro- and microstructural variation is associated with BDNF plasma levels in healthy elderly individuals.Modafinil-Induced Changes in Functional Connectivity in the Cortex and Cerebellum of Healthy Elderly Subjects.Heavy metal ions in normal physiology, toxic stress, and cytoprotection.nNOS(+) striatal neurons, a subpopulation spared in Huntington's Disease, possess functional NMDA receptors but fail to generate mitochondrial ROS in response to an excitotoxic challengeExenatide promotes cognitive enhancement and positive brain metabolic changes in PS1-KI mice but has no effects in 3xTg-AD animals.Alzheimer's disease, metal ions and metal homeostatic therapy.Zinc in the physiology and pathology of the CNS.Early and sustained altered expression of aging-related genes in young 3xTg-AD mice.Ratiometric-pericam-mt, a novel tool to evaluate intramitochondrial zinc.A sodium zinc exchange mechanism is mediating extrusion of zinc in mammalian cells.Characterization of MPP(+)-induced cell death in a dopaminergic neuronal cell line: role of macromolecule synthesis, cytosolic calcium, caspase, and Bcl-2-related proteins.Measurement of intracellular free zinc in living neurons.Staurosporine-induced neuronal apoptosis.Glutamate triggers preferential Zn2+ flux through Ca2+ permeable AMPA channels and consequent ROS production.Mild acidosis enhances AMPA receptor-mediated intracellular zinc mobilization in cortical neurons.Characterization of resting state activity in MCI individuals.The thiol-modifying agent N-ethylmaleimide elevates the cytosolic concentration of free Zn(2+) but not of Ca(2+) in murine cortical neurons.Zn(2+) induces permeability transition pore opening and release of pro-apoptotic peptides from neuronal mitochondria.Medium-chain plasma acylcarnitines, ketone levels, cognition, and gray matter volumes in healthy elderly, mildly cognitively impaired, or Alzheimer's disease subjects.Mitochondrial sequestration and Ca(2+)-dependent release of cytosolic Zn(2+) loads in cortical neurons.Zn2+ currents are mediated by calcium-permeable AMPA/kainate channels in cultured murine hippocampal neurones.The first 17 amino acids of Huntingtin modulate its sub-cellular localization, aggregation and effects on calcium homeostasis.AMPA/kainate receptor-triggered Zn2+ entry into cortical neurons induces mitochondrial Zn2+ uptake and persistent mitochondrial dysfunction.A new mitochondrial fluorescent zinc sensor.
P50
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P50
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Stefano L. Sensi
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P106
P1960
CTAR5_8AAAAJ
P21
P31
P496
0000-0002-0710-2574
P569
2000-01-01T00:00:00Z