MEPE, a new gene expressed in bone marrow and tumors causing osteomalacia
about
Human recombinant endopeptidase PHEX has a strict S1' specificity for acidic residues and cleaves peptides derived from fibroblast growth factor-23 and matrix extracellular phosphoglycoproteinCloning and characterization of FGF23 as a causative factor of tumor-induced osteomalaciaASARM peptides: PHEX-dependent and -independent regulation of serum phosphateDegradation of MEPE, DMP1, and release of SIBLING ASARM-peptides (minhibins): ASARM-peptide(s) are directly responsible for defective mineralization in HYPDentin matrix degradation by host matrix metalloproteinases: inhibition and clinical perspectives toward regenerationExtracellular matrix mineralization in periodontal tissues: Noncollagenous matrix proteins, enzymes, and relationship to hypophosphatasia and X-linked hypophosphatemiaRegulation of bone-renal mineral and energy metabolism: the PHEX, FGF23, DMP1, MEPE ASARM pathwayA unified model for bone-renal mineral and energy metabolismFGF23, PHEX, and MEPE regulation of phosphate homeostasis and skeletal mineralizationSix genes expressed in bones and teeth encode the current members of the SIBLING family of proteinsThree SIBLINGs (small integrin-binding ligand, N-linked glycoproteins) enhance factor H's cofactor activity enabling MCP-like cellular evasion of complement-mediated attackBone sialoprotein and its transcriptional regulatory mechanismProteolytic processing of osteopontin by PHEX and accumulation of osteopontin fragments in Hyp mouse bone, the murine model of X-linked hypophosphatemiaExpression of SIBLINGs and their partner MMPs in salivary glandsRole of matrix extracellular phosphoglycoprotein in the pathogenesis of X-linked hypophosphatemiaIncreased expression of matrix extracellular phosphoglycoprotein (MEPE) in cortical bone of the rat tibia after mechanical loading: identification by oligonucleotide microarrayMatrix extracellular phosphoglycoprotein inhibits phosphate transportTargeted disruption of the osteoblast/osteocyte factor 45 gene (OF45) results in increased bone formation and bone massMEPE is a novel regulator of growth plate cartilage mineralizationGenetic determinants of cardiovascular events among women with migraine: a genome-wide association studyAbnormal presence of the matrix extracellular phosphoglycoprotein-derived acidic serine- and aspartate-rich motif peptide in human hypophosphatemic dentin.Matrix extracellular phosphoglycoprotein (MEPE) is a new bone renal hormone and vascularization modulator.MEPE/OF45 as a new target for sensitizing human tumour cells to DNA damage inducersMepe is expressed during skeletal development and regeneration.A small peptide mimicking the key domain of MEPE/OF45 interacting with CHK1 protects human cells from radiation-induced killing.The molecular background to hypophosphataemic rickets.Adaptive evolution of the matrix extracellular phosphoglycoprotein in mammalsFGF-23 in fibrous dysplasia of bone and its relationship to renal phosphate wastingExpression and processing of small integrin-binding ligand N-linked glycoproteins in mouse odontoblastic cells.Abnormal osteopontin and matrix extracellular phosphoglycoprotein localization, and odontoblast differentiation, in X-linked hypophosphatemic teeth.Characterization of FN1-FGFR1 and novel FN1-FGF1 fusion genes in a large series of phosphaturic mesenchymal tumors.MEPE-derived ASARM peptide inhibits odontogenic differentiation of dental pulp stem cells and impairs mineralization in tooth models of X-linked hypophosphatemiaMultiple quantitative trait locus analysis of bovine chromosome 6 in the Israeli Holstein population by a daughter designSmall integrin-binding ligand N-linked glycoproteins (SIBLINGs): multifunctional proteins in cancerMMP2-cleavage of DMP1 generates a bioactive peptide promoting differentiation of dental pulp stem/progenitor cell.A genome-wide scan for signatures of differential artificial selection in ten cattle breeds.The impairment of osteogenesis in bone sialoprotein (BSP) knockout calvaria cell cultures is cell density dependent.SPR4-peptide alters bone metabolism of normal and HYP mice.Regulation of phosphate transport by fibroblast growth factor 23 (FGF23): implications for disorders of phosphate metabolism.Evidence for a bone-kidney axis regulating phosphate homeostasis.
P2860
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P2860
MEPE, a new gene expressed in bone marrow and tumors causing osteomalacia
description
2000 nî lūn-bûn
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2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
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2000 թվականի հուլիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年學術文章
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MEPE, a new gene expressed in bone marrow and tumors causing osteomalacia
@ast
MEPE, a new gene expressed in bone marrow and tumors causing osteomalacia
@en
MEPE, a new gene expressed in bone marrow and tumors causing osteomalacia
@en-gb
MEPE, a new gene expressed in bone marrow and tumors causing osteomalacia
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MEPE, a new gene expressed in bone marrow and tumors causing osteomalacia
@ast
MEPE, a new gene expressed in bone marrow and tumors causing osteomalacia
@en
MEPE, a new gene expressed in bone marrow and tumors causing osteomalacia
@en-gb
MEPE, a new gene expressed in bone marrow and tumors causing osteomalacia
@nl
prefLabel
MEPE, a new gene expressed in bone marrow and tumors causing osteomalacia
@ast
MEPE, a new gene expressed in bone marrow and tumors causing osteomalacia
@en
MEPE, a new gene expressed in bone marrow and tumors causing osteomalacia
@en-gb
MEPE, a new gene expressed in bone marrow and tumors causing osteomalacia
@nl
P2093
P921
P3181
P356
P1433
P1476
MEPE, a new gene expressed in bone marrow and tumors causing osteomalacia
@en
P2093
P3181
P356
10.1006/GENO.2000.6235
P407
P577
2000-07-01T00:00:00Z