Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors
about
The orphan nuclear receptor LRH-1 and ERα activate GREB1 expression to induce breast cancer cell proliferationFunctional conservation of interactions between a homeodomain cofactor and a mammalian FTZ-F1 homologueA transcriptional inhibitor targeted by the atypical orphan nuclear receptor SHPModulation of human nuclear receptor LRH-1 activity by phospholipids and SHPSynergistic activation of the human orphan nuclear receptor SHP gene promoter by basic helix-loop-helix protein E2A and orphan nuclear receptor SF-1PKA-dependent regulation of the histone lysine demethylase complex PHF2-ARID5BDefinition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesisTranscriptional corepressor SHP recruits SIRT1 histone deacetylase to inhibit LRH-1 transactivationEstrogen and Estrogen Receptor-α-Mediated Transrepression of Bile Salt Export PumpBile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7alpha-hydroxylase gene expressionIdentification of farnesoid X receptor beta as a novel mammalian nuclear receptor sensing lanosterolMutations in the small heterodimer partner gene are associated with mild obesity in Japanese subjectsInvolvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesisSharp, an inducible cofactor that integrates nuclear receptor repression and activationChronic diarrhea due to excessive bile acid synthesis and not defective ileal transport: a new syndrome of defective fibroblast growth factor 19 releaseLiver x receptors in atherosclerosis and inflammationPeroxisome proliferator-activated receptor-gamma coactivator 1alpha (PGC-1alpha) regulates triglyceride metabolism by activation of the nuclear receptor FXRPromotion of liver regeneration/repair by farnesoid X receptor in both liver and intestine in miceEndocrine fibroblast growth factors 15/19 and 21: from feast to famineThe nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicityBile acids inhibit duodenal secretin expression via orphan nuclear receptor small heterodimer partner (SHP)Bile acids: regulation of apoptosis by ursodeoxycholic acidBile acids: regulation of synthesisPancreatic-duodenal homeobox 1 regulates expression of liver receptor homolog 1 during pancreas developmentSF-1 a key player in the development and differentiation of steroidogenic tissuesRole of bile acids in the regulation of the metabolic pathwaysSmall Heterodimer Partner and Innate Immune RegulationBile Acid Metabolism and Signaling in Cholestasis, Inflammation, and CancerControversies in the Mechanism of Total Parenteral Nutrition Induced PathologyBile acid metabolism and signalingThe food matrix and sterol characteristics affect the plasma cholesterol lowering of phytosterol/phytostanolFXR signaling in the enterohepatic systemBile acids as metabolic regulatorsBridging cell surface receptor with nuclear receptors in control of bile acid homeostasisHepatic farnesoid X-receptor isoforms α2 and α4 differentially modulate bile salt and lipoprotein metabolism in miceIdentification of a potent synthetic FXR agonist with an unexpected mode of binding and activationStructural insights into gene repression by the orphan nuclear receptor SHPCrystal Structures of the Nuclear Receptor, Liver Receptor Homolog 1, Bound to Synthetic Agonists Reveal a Novel Mechanism of ActivationNuclear Receptors as Therapeutic Targets in Liver Disease: Are We There Yet?Regulation of fibroblast growth factor 15/19 and 21 on metabolism: in the fed or fasted state
P2860
Q21134778-4D394E36-3EB0-417B-A06F-20FB26A1190DQ24293122-3D727827-EBC5-4A61-8DE6-C695B8583CF2Q24294778-466AC63C-A30A-4874-9AF8-91F6B898DDF4Q24295257-1D7A9CF1-F015-4218-947D-E39A7304C039Q24300149-D06F4F81-6635-43C9-8095-3A52782F6880Q24300856-2DD3D02C-F674-44D8-8D61-B8975FC14836Q24305561-837769F1-8D39-4F40-8E1B-CAD332B85A1AQ24306100-33F2A8F3-41AC-4E6B-B6D9-8D75FEE06E5CQ24318914-5EF48DD0-FDA9-4C9A-9CAA-8D5AB6641AC4Q24336351-CDB1077D-A43F-496B-ACD8-0070745E0086Q24540997-A66D1ABC-F05B-4E04-A83F-DA4ABC58ADFFQ24543970-CAC27BF0-2D34-4600-9D3D-8EF08DE53932Q24564745-889C8130-3562-4648-AD56-2B50E851D55DQ24601805-3D320D21-AFC3-4082-8422-F46BE03B4B20Q24603434-BAEAAB0B-E4AE-4F4F-8C2A-1317037619AFQ24608256-64AA9C71-3A8D-4673-93B3-40EA1E0EAA4FQ24623871-035D8DA2-F093-47F2-A56B-6D452F8E2D0BQ24626582-4A845295-42EC-4679-985E-E7DF685FBF53Q24629260-6304B168-7D3D-40AB-BDCB-B6BA0EF3B1C8Q24630723-22FFB389-802B-47B2-8997-D818FD0555F4Q24648043-55F52758-33AC-4DDB-88BC-17AE17A6E1FEQ24653969-ED402419-32EB-4735-9B60-13094816F331Q24658139-590070B2-50E4-4B16-8577-34DC7D5C4621Q24682440-4157223A-C8D1-487D-BA15-7F5C9DBA841AQ24805943-69180C94-4C9E-45F5-B598-BB3185AC7019Q26738976-ADF8F8E3-3397-4AEB-B7E9-2CBC904F27F6Q26769682-CD36EA6F-C35B-414A-B84A-553516DAF695Q26800206-EEC6EBBD-BF67-4F17-BAFA-E146573F7894Q26865276-306067BB-507A-4131-9F64-AE3419DF1263Q27002873-DB41B827-3028-4546-BEE3-F770E94D2960Q27008082-02BC3967-050A-411A-8A99-8EF7D1687DD1Q27014753-249DE75D-2E4B-49D1-B541-6195CB7D21FBQ27022441-4C48FE52-6B1E-4ADA-BAA0-C488F2C897E2Q27024221-D8281230-9FA8-40FB-97E1-DD42CB63D2D4Q27320737-C9E8FEFC-4724-4AAD-8214-B1D6340C542EQ27650237-833CF447-FE9C-4308-94D3-857D48ED23ADQ27681139-460C392E-2D7B-4E3C-9323-AE1867B71D65Q27728159-0C08C437-0396-477C-8CA3-FE3424522A62Q28066233-50600A8F-15B6-4996-BCBD-E3DBCB8A32F7Q28070054-7F2C1A8F-2F0C-45BC-A347-AAE91819B675
P2860
Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors
description
2000 nî lūn-bûn
@nan
2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors
@ast
Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors
@en
Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors
@en-gb
Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors
@nl
type
label
Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors
@ast
Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors
@en
Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors
@en-gb
Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors
@nl
prefLabel
Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors
@ast
Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors
@en
Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors
@en-gb
Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors
@nl
P2093
P3181
P1433
P1476
Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors
@en
P2093
D J Mangelsdorf
K Schoonjans
M Makishima
P304
P3181
P356
10.1016/S1097-2765(00)00050-2
P407
P50
P577
2000-09-01T00:00:00Z