Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulation
about
The ubiquilin gene family: evolutionary patterns and functional insightsInteraction with a ubiquitin-like protein enhances the ubiquitination and degradation of hepatitis C virus RNA-dependent RNA polymeraseRole of ubiquilin associated with protein-disulfide isomerase in the endoplasmic reticulum in stress-induced apoptotic cell deathThe ubiquitin-like protein PLIC-2 is a negative regulator of G protein-coupled receptor endocytosis.The UBL domain of PLIC-1 regulates aggresome formationAlzheimer's disease-associated ubiquilin-1 regulates presenilin-1 accumulation and aggresome formationUbiquilin functions in autophagy and is degraded by chaperone-mediated autophagyUbiquilin and p97/VCP bind erasin, forming a complex involved in ERADPathogenic mutation of UBQLN2 impairs its interaction with UBXD8 and disrupts endoplasmic reticulum-associated protein degradationUbiquilin regulates presenilin endoproteolysis and modulates gamma-secretase components, Pen-2 and nicastrinGenetic aspects of Alzheimer diseaseUbiquilin-1 is a molecular chaperone for the amyloid precursor proteinRapamycin rescues TDP-43 mislocalization and the associated low molecular mass neurofilament instabilityUbiquitin-like and ubiquitin-associated domain proteins: significance in proteasomal degradationThe ubiquitin-associated domain of hPLIC-2 interacts with the proteasomeDimerization of ubiquilin is dependent upon the central region of the protein: evidence that the monomer, but not the dimer, is involved in binding presenilinsAffinity Makes the Difference: Nonselective Interaction of the UBA Domain of Ubiquilin-1 with Monomeric Ubiquitin and Polyubiquitin ChainsBudding yeast Dsk2p is a polyubiquitin-binding protein that can interact with the proteasomeALS-linked mutations in ubiquilin-2 or hnRNPA1 reduce interaction between ubiquilin-2 and hnRNPA1GABA(A) receptor cell surface number and subunit stability are regulated by the ubiquitin-like protein Plic-1Aggresome formation and neurodegenerative diseases: therapeutic implicationsKaposi's sarcoma-associated herpesvirus K7 induces viral G protein-coupled receptor degradation and reduces its tumorigenicityMIR155 Regulation of Ubiquilin1 and Ubiquilin2: Implications in Cellular Protection and TumorigenesisProtein aggregates and novel presenilin gene variants in idiopathic dilated cardiomyopathyUbiquitin domain proteins in disease.Role of X11 and ubiquilin as in vivo regulators of the amyloid precursor protein in DrosophilaRAWUL: a new ubiquitin-like domain in PRC1 ring finger proteins that unveils putative plant and worm PRC1 orthologsReduced body weight gain in ubiquilin-1 transgenic mice is associated with increased expression of energy-sensing proteinsA novel ALS-associated variant in UBQLN4 regulates motor axon morphogenesisTransgenic Drosophila models of Alzheimer's disease and tauopathiesUbiquilin modifies TDP-43 toxicity in a Drosophila model of amyotrophic lateral sclerosis (ALS).Diversity in the architecture of ATLs, a family of plant ubiquitin-ligases, leads to recognition and targeting of substrates in different cellular environmentsUBQLN1 interacts with SPEM1 and participates in spermiogenesisPresenilin-1 regulates induction of hypoxia inducible factor-1α: altered activation by a mutation associated with familial Alzheimer's diseaseProtein aggregation and degradation mechanisms in neurodegenerative diseasesGABAA receptor trafficking-mediated plasticity of inhibitory synapses.Ubiquilin 2 is not associated with tau pathologySignature changes in ubiquilin expression in the R6/2 mouse model of Huntington's disease.Mutant Atp13a2 proteins involved in parkinsonism are degraded by ER-associated degradation and sensitize cells to ER-stress induced cell death.Defective Proteasome Delivery of Polyubiquitinated Proteins by Ubiquilin-2 Proteins Containing ALS Mutations.
P2860
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P2860
Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulation
description
2000 nî lūn-bûn
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2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
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2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Identification of ubiquilin, a ...... resenilin protein accumulation
@ast
Identification of ubiquilin, a ...... resenilin protein accumulation
@en
Identification of ubiquilin, a ...... resenilin protein accumulation
@en-gb
Identification of ubiquilin, a ...... resenilin protein accumulation
@nl
type
label
Identification of ubiquilin, a ...... resenilin protein accumulation
@ast
Identification of ubiquilin, a ...... resenilin protein accumulation
@en
Identification of ubiquilin, a ...... resenilin protein accumulation
@en-gb
Identification of ubiquilin, a ...... resenilin protein accumulation
@nl
prefLabel
Identification of ubiquilin, a ...... resenilin protein accumulation
@ast
Identification of ubiquilin, a ...... resenilin protein accumulation
@en
Identification of ubiquilin, a ...... resenilin protein accumulation
@en-gb
Identification of ubiquilin, a ...... resenilin protein accumulation
@nl
P2093
P2860
P3181
P356
P1476
Identification of ubiquilin, a ...... resenilin protein accumulation
@en
P2093
P2860
P304
P3181
P356
10.1083/JCB.151.4.847
P407
P577
2000-11-13T00:00:00Z