KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel
about
Differential association between HERG and KCNE1 or KCNE2The KCNE2 K+ channel regulatory subunit: Ubiquitous influence, complex pathobiologyKCNE2 protein is more abundant in ventricles than in atria and can accelerate hERG protein degradation in a phosphorylation-dependent mannerp11, an annexin II subunit, an auxiliary protein associated with the background K+ channel, TASK-1KCNE5 induces time- and voltage-dependent modulation of the KCNQ1 current.Identification of a KCNE2 gain-of-function mutation in patients with familial atrial fibrillation.KCNE4 is an inhibitory subunit to Kv1.1 and Kv1.3 potassium channels.Interaction of KCNE subunits with the KCNQ1 K+ channel poreKCNE4 is an inhibitory subunit to the KCNQ1 channelA comparison of currents carried by HERG, with and without coexpression of MiRP1, and the native rapid delayed rectifier current. Is MiRP1 the missing link?KCNE variants reveal a critical role of the beta subunit carboxyl terminus in PKA-dependent regulation of the IKs potassium channelDynamic partnership between KCNQ1 and KCNE1 and influence on cardiac IKs current amplitude by KCNE2Inactivation as a new regulatory mechanism for neuronal Kv7 channelsIon Channels in the HeartThe KCNQ1 channel - remarkable flexibility in gating allows for functional versatilityExpression and coassociation of ERG1, KCNQ1, and KCNE1 potassium channel proteins in horse heartFunctional significance of K+ channel β-subunit KCNE3 in auditory neuronsGain-of-function mutations in potassium channel subunit KCNE2 associated with early-onset lone atrial fibrillationKCNE2 forms potassium channels with KCNA3 and KCNQ1 in the choroid plexus epitheliumKCNE2 and the K (+) channel: the tail wagging the dogThe KCNQ1-KCNE2 K⁺ channel is required for adequate thyroid I⁻ uptakeA shared mechanism for lipid- and beta-subunit-coordinated stabilization of the activated K+ channel voltage sensorDisruption of the K+ channel beta-subunit KCNE3 reveals an important role in intestinal and tracheal Cl- transportIKs channels open slowly because KCNE1 accessory subunits slow the movement of S4 voltage sensors in KCNQ1 pore-forming subunitsTargeted deletion of kcne2 impairs ventricular repolarization via disruption of I(K,slow1) and I(to,f)An LQTS6 MiRP1 mutation suppresses pacemaker current and is associated with sinus bradycardiaGenetic dissection reveals unexpected influence of beta subunits on KCNQ1 K+ channel polarized trafficking in vivoSubcellular localization of the delayed rectifier K(+) channels KCNQ1 and ERG1 in the rat heartStoichiometry of the KCNQ1 - KCNE1 ion channel complex.miR-19b Regulates Ventricular Action Potential Duration in Zebrafish.KCNQ1 mutations in patients with a family history of lethal cardiac arrhythmias and sudden death.A KCNQ1 mutation causes a high penetrance for familial atrial fibrillation.KCNE1 constrains the voltage sensor of Kv7.1 K+ channels.Functional interactions between KCNE1 C-terminus and the KCNQ1 channel.Differential modulations of KCNQ1 by auxiliary proteins KCNE1 and KCNE2KCNE2 modulation of Kv4.3 current and its potential role in fatal rhythm disorders.Molecular diversity and regulation of renal potassium channels.Novel Kv7.1-phosphatidylinositol 4,5-bisphosphate interaction sites uncovered by charge neutralization scanningCardiac arrhythmia and thyroid dysfunction: a novel genetic link.Targeted deletion of Kcne2 impairs HCN channel function in mouse thalamocortical circuits.
P2860
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P2860
KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel
description
2000 nî lūn-bûn
@nan
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel
@ast
KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel
@en
KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel
@en-gb
KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel
@nl
type
label
KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel
@ast
KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel
@en
KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel
@en-gb
KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel
@nl
prefLabel
KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel
@ast
KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel
@en
KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel
@en-gb
KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel
@nl
P2093
P2860
P3181
P356
P1433
P1476
KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel
@en
P2093
P2860
P304
P3181
P356
10.1093/EMBOJ/19.23.6326
P407
P577
2000-12-01T00:00:00Z