CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling
about
High CD45 surface expression determines relapse risk in children with precursor B-cell and T-cell acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocolSubdomain X of the kinase domain of Lck binds CD45 and facilitates dephosphorylationIdentification of a nuclear Stat1 protein tyrosine phosphataseIntegrin CD11a cytoplasmic tail interacts with the CD45 membrane-proximal protein tyrosine phosphatase domain 1Protein-tyrosine phosphatase PCP-2 inhibits beta-catenin signaling and increases E-cadherin-dependent cell adhesionECHS1 interacts with STAT3 and negatively regulates STAT3 signalingPrinciples of interleukin (IL)-6-type cytokine signalling and its regulationPositive and negative regulation of T-cell activation through kinases and phosphatasesSignaling by STATsProtein tyrosine phosphatases as wardens of STAT signalingLeft atrial appendages from adult hearts contain a reservoir of diverse cardiac progenitor cellsBlocking of Interferon-Induced Jak-Stat Signaling by Japanese Encephalitis Virus NS5 through a Protein Tyrosine Phosphatase-Mediated MechanismSignal transducer and activator of transcription 3 in myeloid-derived suppressor cells: an opportunity for cancer therapyInterleukin-6, CD45 and the src-kinases in myeloma cell proliferation77 C/G mutation in the tyrosine phosphatase CD45 gene and autoimmune hepatitis: evidence for a genetic linkReciprocal regulation of lymphocyte activation by tyrosine kinases and phosphatasesProtein tyrosine phosphatases in the JAK/STAT pathwayAnti-CD45RO suppresses human immunodeficiency virus type 1 replication in microglia: role of Hck tyrosine kinase and implications for AIDS dementia.CD45 ligation expands Tregs by promoting interactions with DCsRole of STAT3 in cancer metastasis and translational advances.CD45RB is a novel molecular therapeutic target to inhibit Abeta peptide-induced microglial MAPK activation.Autoimmunity-associated protein tyrosine phosphatase PEP negatively regulates IFN-α receptor signalingCD45RC isoform expression identifies functionally distinct T cell subsets differentially distributed between healthy individuals and AAV patients.A quantitative high-throughput screen for modulators of IL-6 signaling: a model for interrogating biological networks using chemical librariesCongenic interval of CD45/Ly-5 congenic mice contains multiple genes that may influence hematopoietic stem cell engraftment.Protein phosphatase 2A regulates interleukin-2 receptor complex formation and JAK3/STAT5 activation.MiR-155 induction in microglial cells suppresses Japanese encephalitis virus replication and negatively modulates innate immune responses.Cell Connections by Tunneling Nanotubes: Effects of Mitochondrial Trafficking on Target Cell Metabolism, Homeostasis, and Response to Therapy.Cluster of differentiation 45 activation is crucial in interleukin-10-dependent tumor-associated dendritic cell differentiation.Stat3: linking inflammation to epithelial cancer - more than a "gut" feeling?The molecular regulation of Janus kinase (JAK) activationProtein-tyrosine phosphatase MEG2 is expressed by human neutrophils. Localization to the phagosome and activation by polyphosphoinositides.Prospective isolation of human clonogenic common myeloid progenitors.γ-Tocotrienol but not γ-tocopherol blocks STAT3 cell signaling pathway through induction of protein-tyrosine phosphatase SHP-1 and sensitizes tumor cells to chemotherapeutic agents.Protein tyrosine phosphatases as potential therapeutic targets.Thymoquinone inhibits proliferation, induces apoptosis and chemosensitizes human multiple myeloma cells through suppression of signal transducer and activator of transcription 3 activation pathwayInterferon-stimulated genes: a complex web of host defenses.HIV-1 gp120-mediated apoptosis of T cells is regulated by the membrane tyrosine phosphatase CD45.T lymphocyte activation--an inside overview.Spinning molecular immunology into successful immunotherapy.
P2860
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P2860
CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling
@ast
CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling
@en
CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling
@en-gb
CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling
@nl
type
label
CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling
@ast
CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling
@en
CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling
@en-gb
CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling
@nl
prefLabel
CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling
@ast
CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling
@en
CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling
@en-gb
CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling
@nl
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P921
P3181
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P1476
CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling
@en
P2093
C D Richardson
C Krawczyk
D M Rothstein
E Griffiths
G Koretzky
G Welstead
J Irie-Sasaki
J M Penninger
P2888
P304
P3181
P356
10.1038/35053086
P407
P577
2001-01-18T00:00:00Z
P5875
P6179
1023226465