The Abl interactor proteins localize to sites of actin polymerization at the tips of lamellipodia and filopodia
about
The eps8 family of proteins links growth factor stimulation to actin reorganization generating functional redundancy in the Ras/Rac pathwayAbi-1 forms an epidermal growth factor-inducible complex with Cbl: role in receptor endocytosisNESH (Abi-3) is present in the Abi/WAVE complex but does not promote c-Abl-mediated phosphorylationA WASp-VASP complex regulates actin polymerization at the plasma membrane.Abelson interacting protein 1 (Abi-1) is essential for dendrite morphogenesis and synapse formationRegulation of actin cytoskeleton architecture by Eps8 and Abi1.Critical role of actin-associated proteins in smooth muscle contraction, cell proliferation, airway hyperresponsiveness and airway remodelingGleevec, an Abl family inhibitor, produces a profound change in cell shape and migrationERK reinforces actin polymerization to power persistent edge protrusion during motility.Differential regulation of macropinocytosis by Abi1/Hssh3bp1 isoformsMIG-10 functions with ABI-1 to mediate the UNC-6 and SLT-1 axon guidance signaling pathwaysNovel roles of formin mDia2 in lamellipodia and filopodia formation in motile cellsAbelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activationAbl interactor 1 promotes tyrosine 296 phosphorylation of mammalian enabled (Mena) by c-Abl kinaseF-actin-dependent regulation of NESH dynamics in rat hippocampal neuronsRegulation of cell shape by Cdc42 is mediated by the synergic actin-bundling activity of the Eps8-IRSp53 complexFormation of cellular projections in neural progenitor cells depends on SK3 channel activitySra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation.ABI2-deficient mice exhibit defective cell migration, aberrant dendritic spine morphogenesis, and deficits in learning and memoryModulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extensionMechanism of filopodia initiation by reorganization of a dendritic network.Abl interactor 1 (Abi-1) wave-binding and SNARE domains regulate its nucleocytoplasmic shuttling, lamellipodium localization, and wave-1 levels.Phosphoinositide 3-Kinase C2beta regulates cytoskeletal organization and cell migration via Rac-dependent mechanisms.Arp2/3 complex interactions and actin network turnover in lamellipodia.The c-Abl tyrosine kinase regulates actin remodeling at the immune synapseEssential role for Abi1 in embryonic survival and WAVE2 complex integrityDiffusion, capture and recycling of SCAR/WAVE and Arp2/3 complexes observed in cells by single-molecule imaging.Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation.Abi is required for modulation and stability but not localization or activation of the SCAR/WAVE complexLamellipodin and the Scar/WAVE complex cooperate to promote cell migration in vivo.Effect of thyroid hormone responsive protein (THRP) expression on PC12 cell survival.F- and G-actin concentrations in lamellipodia of moving cellsExpression and Y435-phosphorylation of Abelson interactor 1 (Abi1) promotes tumour cell adhesion, extracellular matrix degradation and invasion by colorectal carcinoma cells.The actin-cytoskeleton pathway and its potential role in inflammatory bowel disease-associated human colorectal cancer.NESH regulates dendritic spine morphology and synapse formation.Expression of Abelson interactor 1 (Abi1) correlates with inflammation, KRAS mutation and adenomatous change during colonic carcinogenesis.Abl-interactor-1 (Abi1) has a role in cardiovascular and placental development and is a binding partner of the alpha4 integrin.Mechanisms of plasma membrane targeting of formin mDia2 through its amino terminal domains.Role of fascin in filopodial protrusionThe role of the lens actin cytoskeleton in fiber cell elongation and differentiation.
P2860
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P2860
The Abl interactor proteins localize to sites of actin polymerization at the tips of lamellipodia and filopodia
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The Abl interactor proteins lo ...... of lamellipodia and filopodia
@ast
The Abl interactor proteins lo ...... of lamellipodia and filopodia
@en
The Abl interactor proteins lo ...... of lamellipodia and filopodia
@en-gb
The Abl interactor proteins lo ...... of lamellipodia and filopodia
@nl
type
label
The Abl interactor proteins lo ...... of lamellipodia and filopodia
@ast
The Abl interactor proteins lo ...... of lamellipodia and filopodia
@en
The Abl interactor proteins lo ...... of lamellipodia and filopodia
@en-gb
The Abl interactor proteins lo ...... of lamellipodia and filopodia
@nl
prefLabel
The Abl interactor proteins lo ...... of lamellipodia and filopodia
@ast
The Abl interactor proteins lo ...... of lamellipodia and filopodia
@en
The Abl interactor proteins lo ...... of lamellipodia and filopodia
@en-gb
The Abl interactor proteins lo ...... of lamellipodia and filopodia
@nl
P2093
P1433
P1476
The Abl interactor proteins lo ...... of lamellipodia and filopodia
@en
P2093
A M Pendergast
K D Courtney
P356
10.1016/S0960-9822(01)00239-1
P407
P577
2001-06-05T00:00:00Z