about
Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cellsThermodynamics of beta-catenin-ligand interactions: the roles of the N- and C-terminal tails in modulating binding affinityA direct beta-catenin-independent interaction between androgen receptor and T cell factor 4The RNA aptamer disrupts protein-protein interaction between beta-catenin and nuclear factor-kappaB p50 and regulates the expression of C-reactive proteinWnt/beta-catenin signaling and small molecule inhibitorsAn intrinsically labile α-helix abutting the BCL9-binding site of β-catenin is required for its inhibition by carnosic acidThe Wnt-dependent signaling pathways as target in oncology drug discoveryT-cell factor 4N (TCF-4N), a novel isoform of mouse TCF-4, synergizes with beta-catenin to coactivate C/EBPalpha and steroidogenic factor 1 transcription factorsThe many faces and functions of β-cateninCrystal Structure of a Full-Length β-CateninThe C. elegans SYS-1 Protein Is a Bona Fide β-CateninBiochemical and Structural Characterization of β-Catenin Interactions with Nonphosphorylated and CK2-Phosphorylated Lef-1Structural basis of coactivation of liver receptor homolog-1 by -cateninAcetylation of beta-catenin by p300 regulates beta-catenin-Tcf4 interactionStructural characterization of partially disordered human Chibby: insights into its function in the Wnt-signaling pathwayDrug development against metastasis-related genes and their pathways: A rationale for cancer therapyDevelopment of GMDR-GPU for gene-gene interaction analysis and its application to WTCCC GWAS data for type 2 diabetesA small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected]KLF4 interacts with beta-catenin/TCF4 and blocks p300/CBP recruitment by beta-catenin.A beta-catenin/TCF-coordinated chromatin loop at MYC integrates 5' and 3' Wnt responsive enhancersMolecular docking studies of flavonoids for their inhibition pattern against β-catenin and pharmacophore model generation from experimentally known flavonoids to fabricate more potent inhibitors for Wnt signaling pathwayTargeting protein-protein interactions for therapeutic intervention: a challenge for the future.Hippo pathway phylogenetics predicts monoubiquitylation of Salvador and Merlin/Nf2A new look at TCF and beta-catenin through the lens of a divergent C. elegans Wnt pathwayT-cell factors: turn-ons and turn-offsEsculetin suppresses proliferation of human colon cancer cells by directly targeting β-catenin.The β-catenin/Tcf4/survivin signaling maintains a less differentiated phenotype and high proliferative capacity of human corneal epithelial progenitor cells.Purification, crystallization and preliminary X-ray diffraction studies of the β-catenin homolog HMP-2 from Caenorhabditis elegans.β-Catenin recognizes a specific RNA motif in the cyclooxygenase-2 mRNA 3'-UTR and interacts with HuR in colon cancer cellsStructure-based mutational analysis of ICAT residues mediating negative regulation of β-catenin co-transcriptional activityCell type-specific binding patterns reveal that TCF7L2 can be tethered to the genome by association with GATA3.Molecular plasticity of beta-catenin: new insights from single-molecule measurements and MD simulation.Structures of designed armadillo-repeat proteins show propagation of inter-repeat interface effectsFunctional analysis of TCF7L2 genetic variants associated with type 2 diabetes.TCF/LEFs and Wnt signaling in the nucleus.Genome-wide ChIP-seq analysis of TCF4 binding regions in colorectal cancer cellsDiscovery of small molecule inhibitors of the Wnt/β-catenin signaling pathway by targeting β-catenin/Tcf4 interactions.The role of β-catenin in the initiation and metastasis of TA2 mice spontaneous breast cancer.Inference of hierarchical regulatory network of TCF7L2 binding sites in MCF7 cell line.Endothelial NO Synthase-Dependent S-Nitrosylation of β-Catenin Prevents Its Association with TCF4 and Inhibits Proliferation of Endothelial Cells Stimulated by Wnt3a.
P2860
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P2860
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
name
Structure of a human Tcf4-beta-catenin complex
@ast
Structure of a human Tcf4-beta-catenin complex
@en
Structure of a human Tcf4-beta-catenin complex
@en-gb
Structure of a human Tcf4-beta-catenin complex
@nl
type
label
Structure of a human Tcf4-beta-catenin complex
@ast
Structure of a human Tcf4-beta-catenin complex
@en
Structure of a human Tcf4-beta-catenin complex
@en-gb
Structure of a human Tcf4-beta-catenin complex
@nl
prefLabel
Structure of a human Tcf4-beta-catenin complex
@ast
Structure of a human Tcf4-beta-catenin complex
@en
Structure of a human Tcf4-beta-catenin complex
@en-gb
Structure of a human Tcf4-beta-catenin complex
@nl
P2093
P356
P1476
Structure of a human Tcf4-beta-catenin complex
@en
P2093
M Lepourcelet
R A Shivdasani
P2888
P304
P356
10.1038/NSB720
P407
P577
2001-12-01T00:00:00Z
P5875
P6179
1028113803