miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifs
about
Structural basis for the Nanos-mediated recruitment of the CCR4-NOT complex and translational repressionThe structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complexDefining a new role of GW182 in maintaining miRNA stabilityThe interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targetsC2ORF29/CNOT11 and CNOT10 form a new module of the CCR4-NOT complexNOT10 and C2orf29/NOT11 form a conserved module of the CCR4-NOT complex that docks onto the NOT1 N-terminal domainPhosphorylation at intrinsically disordered regions of PAM2 motif-containing proteins modulates their interactions with PABPC1 and influences mRNA fateGW182 proteins cause PABP dissociation from silenced miRNA targets in the absence of deadenylationStructural basis for the recruitment of the human CCR4-NOT deadenylase complex by tristetraprolinmiRNA-mediated gene silencing by translational repression followed by mRNA deadenylation and decayRibosome profiling shows that miR-430 reduces translation before causing mRNA decay in zebrafishThe organization and regulation of mRNA-protein complexesRNA Binding Proteins in the miRNA PathwayCcr4-Not complex: the control freak of eukaryotic cellsThe role of miRNAs in regulating gene expression networksThe panorama of miRNA-mediated mechanisms in mammalian cellsBiogenesis and mechanism of action of small non-coding RNAs: insights from the point of view of structural biologyThe role of mammalian poly(A)-binding proteins in co-ordinating mRNA turnoverHeterogeneity and complexity within the nuclease module of the Ccr4-Not complexConsolidation and translation regulationThe CCR4-NOT complex mediates deadenylation and degradation of stem cell mRNAs and promotes planarian stem cell differentiationA direct interaction between DCP1 and XRN1 couples mRNA decapping to 5' exonucleolytic degradationStructural basis for Pan3 binding to Pan2 and its function in mRNA recruitment and deadenylationStructure and RNA-binding properties of the Not1-Not2-Not5 module of the yeast Ccr4-Not complexStructure and assembly of the NOT module of the human CCR4-NOT complexThe structure of the Pan2-Pan3 core complex reveals cross-talk between deadenylase and pseudokinaseUsing microRNA as an alternative treatment for hyperlipidemia and cardiovascular disease: cardio-miRs in the pipelineDistinct modes of recruitment of the CCR4-NOT complex by Drosophila and vertebrate NanosFunction and Regulation of MicroRNAs and Their Potential as Biomarkers in Paediatric Liver DiseaseTrinucleotide repeat containing 6a (Tnrc6a)-mediated microRNA function is required for development of yolk sac endodermMultivariate proteomic profiling identifies novel accessory proteins of coated vesiclesmiR-23b regulates cytoskeletal remodeling, motility and metastasis by directly targeting multiple transcriptsIntegrative data analysis indicates an intrinsic disordered domain character of Argonaute-binding motifs.Novel roles of the multi-functional CCR4-NOT complex in post-transcriptional regulation.Deadenylation of mRNA by the CCR4-NOT complex in Drosophila: molecular and developmental aspects.Traversing the RNA world.Multifunctional roles of the mammalian CCR4-NOT complex in physiological phenomena.The regulation of mRNA stability in mammalian cells: 2.0.The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC.Poly(A) binding proteins: are they all created equal?
P2860
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P2860
miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifs
description
2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
miRNA repression involves GW18 ...... conserved W-containing motifs
@ast
miRNA repression involves GW18 ...... conserved W-containing motifs
@en
miRNA repression involves GW18 ...... conserved W-containing motifs
@en-gb
miRNA repression involves GW18 ...... conserved W-containing motifs
@nl
type
label
miRNA repression involves GW18 ...... conserved W-containing motifs
@ast
miRNA repression involves GW18 ...... conserved W-containing motifs
@en
miRNA repression involves GW18 ...... conserved W-containing motifs
@en-gb
miRNA repression involves GW18 ...... conserved W-containing motifs
@nl
prefLabel
miRNA repression involves GW18 ...... conserved W-containing motifs
@ast
miRNA repression involves GW18 ...... conserved W-containing motifs
@en
miRNA repression involves GW18 ...... conserved W-containing motifs
@en-gb
miRNA repression involves GW18 ...... conserved W-containing motifs
@nl
P2093
P2860
P921
P3181
P356
P1476
miRNA repression involves GW18 ...... conserved W-containing motifs
@en
P2093
Hansruedi Mathys
Jakob T Zipprich
Marija Colic
Marina Chekulaeva
Roy Parker
Witold Filipowicz
P2860
P2888
P304
P3181
P356
10.1038/NSMB.2166
P407
P50
P577
2011-10-07T00:00:00Z
P5875
P6179
1020598684