Non-polarized targeting of AE1 causes autosomal dominant distal renal tubular acidosis
about
Physical and functional links between anion exchanger-1 and sodium pumpA novel missense mutation in AE1 causing autosomal dominant distal renal tubular acidosis retains normal transport function but is mistargeted in polarized epithelial cellsNaked2 acts as a cargo recognition and targeting protein to ensure proper delivery and fusion of TGF-alpha containing exocytic vesicles at the lower lateral membrane of polarized MDCK cells.Mutations in VPS33B, encoding a regulator of SNARE-dependent membrane fusion, cause arthrogryposis-renal dysfunction-cholestasis (ARC) syndromeThe ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cellsKidney stone disease.Molecular physiology and genetics of Na+-independent SLC4 anion exchangersProtein trafficking defects in inherited kidney diseasesGlyceraldehyde 3-phosphate dehydrogenase is required for band 3 (anion exchanger 1) membrane residency in the mammalian kidneyNBCe1A dimer assemble visualized by bimolecular fluorescence complementationMechanisms regulating tissue-specific polarity of monocarboxylate transporters and their chaperone CD147 in kidney and retinal epitheliaSpecification of ion transport cells in the Xenopus larval skin.Pathogenesis and treatment of autosomal-dominant nephrogenic diabetes insipidus caused by an aquaporin 2 mutation.The role of aspartic acid residues 405 and 416 of the kidney isotype of sodium-bicarbonate cotransporter 1 in its targeting to the plasma membrane.Mutation conferring apical-targeting motif on AE1 exchanger causes autosomal dominant distal RTA.Molecular physiology of SLC4 anion exchangers.Adaptor protein 1 complexes regulate intracellular trafficking of the kidney anion exchanger 1 in epithelial cellsSLC4 base (HCO3 -, CO3 2-) transporters: classification, function, structure, genetic diseases, and knockout models.Apical targeting and endocytosis of the sialomucin endolyn are essential for establishment of zebrafish pronephric kidney functionUnraveling trafficking of the kidney anion exchanger 1 in polarized MDCK epithelial cells.Inherited renal acidoses.A new class of endoplasmic reticulum export signal PhiXPhiXPhi for transmembrane proteins and its selective interaction with Sec24CBand 3 Courcouronnes (Ser667Phe): a trafficking mutant differentially rescued by wild-type band 3 and glycophorin A.Molecular mechanisms of autosomal dominant and recessive distal renal tubular acidosis caused by SLC4A1 (AE1) mutations.Antagonistic roles of ESCRT and Vps class C/HOPS complexes in the recycling of yeast membrane proteinsPDLIM5 links kidney anion exchanger 1 (kAE1) to ILK and is required for membrane targeting of kAE1.Anion exchanger 1 in red blood cells and kidney: Band 3's in a pod.Mis-trafficking of bicarbonate transporters: implications to human diseases.Trafficking defects of a novel autosomal recessive distal renal tubular acidosis mutant (S773P) of the human kidney anion exchanger (kAE1).The carboxyl-terminally truncated kidney anion exchanger 1 R901X dRTA mutant is unstable at the plasma membrane.Degradation mechanism of a Golgi-retained distal renal tubular acidosis mutant of the kidney anion exchanger 1 in renal cells.Ammonia Transporters and Their Role in Acid-Base Balance.Cell surface rescue of kidney anion exchanger 1 mutants by disruption of chaperone interactions.Band 3 Edmonton I, a novel mutant of the anion exchanger 1 causing spherocytosis and distal renal tubular acidosis.Expression and interaction of two compound heterozygous distal renal tubular acidosis mutants of kidney anion exchanger 1 in epithelial cells.The human NBCe1-A mutant R881C, associated with proximal renal tubular acidosis, retains function but is mistargeted in polarized renal epithelia.Polarized apical sorting of guanylyl cyclase C is specified by a cytosolic signal.Trafficking defects of the Southeast Asian ovalocytosis deletion mutant of anion exchanger 1 membrane proteins.Zebrafish slc4a2/ae2 anion exchanger: cDNA cloning, mapping, functional characterization, and localization.Missense mutations in Na+:HCO3- cotransporter NBC1 show abnormal trafficking in polarized kidney cells: a basis of proximal renal tubular acidosis.
P2860
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P2860
Non-polarized targeting of AE1 causes autosomal dominant distal renal tubular acidosis
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Non-polarized targeting of AE1 causes autosomal dominant distal renal tubular acidosis
@ast
Non-polarized targeting of AE1 causes autosomal dominant distal renal tubular acidosis
@en
Non-polarized targeting of AE1 causes autosomal dominant distal renal tubular acidosis
@nl
type
label
Non-polarized targeting of AE1 causes autosomal dominant distal renal tubular acidosis
@ast
Non-polarized targeting of AE1 causes autosomal dominant distal renal tubular acidosis
@en
Non-polarized targeting of AE1 causes autosomal dominant distal renal tubular acidosis
@nl
prefLabel
Non-polarized targeting of AE1 causes autosomal dominant distal renal tubular acidosis
@ast
Non-polarized targeting of AE1 causes autosomal dominant distal renal tubular acidosis
@en
Non-polarized targeting of AE1 causes autosomal dominant distal renal tubular acidosis
@nl
P2093
P356
P1433
P1476
Non-polarized targeting of AE1 causes autosomal dominant distal renal tubular acidosis
@en
P2093
Annabel N Smith
Gudrun Ihrke
Jenny P Poon
Mark A J Devonald
P2888
P356
10.1038/NG1082
P407
P577
2003-02-01T00:00:00Z
P6179
1043019931