BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER
about
ERdj5 is the ER reductase that catalyzes the removal of non-native disulfides and correct folding of the LDL receptorBiP and its nucleotide exchange factors Grp170 and Sil1: mechanisms of action and biological functionsERAD and protein import defects in a sec61 mutant lacking ER-lumenal loop 7.Hsp90 modulates PPARγ activity in a mouse model of nonalcoholic fatty liver disease.Dynamic interaction of the sec translocon with the chaperone PpiDAbsence of BiP co-chaperone DNAJC3 causes diabetes mellitus and multisystemic neurodegenerationDirect imaging of ER calcium with targeted-esterase induced dye loading (TED)The signal sequence influences post-translational ER translocation at distinct stages.Targeting cell migration and the endoplasmic reticulum stress response with calmodulin antagonists: a clinically tested small molecule phenocopy of SEC62 gene silencing in human tumor cells.Increased water flux induced by an aquaporin-1/carbonic anhydrase II interactionProtection of Human Pancreatic Islets from Lipotoxicity by Modulation of the TransloconLuminal Ca2+ depletion during the unfolded protein response in Xenopus oocytes: cause and consequence.Sigma1 receptors inhibit store-operated Ca2+ entry by attenuating coupling of STIM1 to Orai1Cloning, expression, purification and preliminary X-ray diffraction studies of a novel AB₅ toxin.Activation of the EIF2α/ATF4 and ATF6 Pathways in DU-145 Cells by Boric Acid at the Concentration Reported in Men at the US Mean Boron Intake.Protein folding in the endoplasmic reticulumSignaling pathways from the endoplasmic reticulum and their roles in diseaseThe Sec translocon mediated protein transport in prokaryotes and eukaryotes.Protein transport into the human ER and related diseases, Sec61-channelopathies.ERAD and how viruses exploit it.Cardioprotection in ischaemia-reperfusion injury: novel mechanisms and clinical translation.Role of endoplasmic reticulum stress signalling in diabetic endothelial dysfunction and atherosclerosis.HSPA5 Gene encoding Hsp70 chaperone BiP in the endoplasmic reticulum.Endoplasmic reticulum-resident selenoproteins as regulators of calcium signaling and homeostasis.Unlocking the Bacterial SecY Translocon.Co-chaperone Specificity in Gating of the Polypeptide Conducting Channel in the Membrane of the Human Endoplasmic Reticulum.Interaction of Pseudomonas aeruginosa Exotoxin A with the human Sec61 complex suppresses passive calcium efflux from the endoplasmic reticulum.Mechanistic insights into the inhibition of Sec61-dependent co- and post-translational translocation by mycolactone.Defective ER associated degradation of a model luminal substrate in yeast carrying a mutation in the 4th ER luminal loop of Sec61p.Overexpression of sphingosine-1-phosphate lyase protects insulin-secreting cells against cytokine toxicity.Age-related cataracts: Role of unfolded protein response, Ca2+ mobilization, epigenetic DNA modifications, and loss of Nrf2/Keap1 dependent cytoprotection.An Update on Sec61 Channel Functions, Mechanisms, and Related Diseases.Novel galeterone analogs act independently of AR and AR-V7 for the activation of the unfolded protein response and induction of apoptosis in the CWR22Rv1 prostate cancer cell model.Inhibitors of protein translocation across membranes of the secretory pathway: novel antimicrobial and anticancer agents.Endoplasmic Reticulum Transport of Glutathione by Sec61 Is Regulated by Ero1 and Bip.Tracking Effects of SIL1 Increase: Taking a Closer Look Beyond the Consequences of Elevated Expression Level.Chaperone-Mediated Sec61 Channel Gating during ER Import of Small Precursor Proteins Overcomes Sec61 Inhibitor-Reinforced Energy Barrier.Nogo-C regulates post myocardial infarction fibrosis through the interaction with ER Ca2+ leakage channel Sec61α in mouse hearts.BiP-mediated closing of the Sec61 channel limits Ca2+leakage from the ERAXER is an ATP/ADP exchanger in the membrane of the endoplasmic reticulum
P2860
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P2860
BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER
description
2012 nî lūn-bûn
@nan
2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER
@ast
BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER
@en
BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER
@en-gb
BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER
@nl
type
label
BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER
@ast
BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER
@en
BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER
@en-gb
BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER
@nl
prefLabel
BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER
@ast
BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER
@en
BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER
@en-gb
BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER
@en
P2093
Adolfo Cavalié
James C Paton
Johanna Dudek
Johannes Linxweiler
Martin Jung
Nico Schäuble
Richard Zimmermann
Sabine Cappel
Stefan Schorr
P2860
P304
P3181
P356
10.1038/EMBOJ.2012.189
P407
P577
2012-08-01T00:00:00Z