Human triose-phosphate isomerase deficiency: a single amino acid substitution results in a thermolabile enzyme
about
Triose phosphate isomerase deficiency is caused by altered dimerization--not catalytic inactivity--of the mutant enzymesThyroid-stimulating hormone (TSH) deficiency caused by a single base substitution in the CAGYC region of the beta-subunitHuman liver type pyruvate kinase: complete amino acid sequence and the expression in mammalian cellsHuman triosephosphate isomerase deficiency resulting from mutation of Phe-240Crystal structure of recombinant human triosephosphate isomerase at 2.8 A resolution. Triosephosphate isomerase-related human genetic disorders and comparison with the trypanosomal enzymeDrosophila model of human inherited triosephosphate isomerase deficiency glycolytic enzymopathyMolecular analysis of a series of alleles in humans with reduced activity at the triosephosphate isomerase locusStructural basis of human triosephosphate isomerase deficiency: mutation E104D is related to alterations of a conserved water network at the dimer interfaceDifferent contribution of conserved amino acids to the global properties of triosephosphate isomerasesAnalysis of homodimeric protein interfaces by graph-spectral methods.Protein crystallography and infectious diseases.Hsp70- and Hsp90-mediated proteasomal degradation underlies TPI sugarkill pathogenesis in Drosophila.Molecular identification, immunolocalization, and characterization of Clonorchis sinensis triosephosphate isomerase.Structure and Stability of the Dimeric Triosephosphate Isomerase from the Thermophilic Archaeon Thermoplasma acidophilum.Screening the 3' region of the polycystic kidney disease 1 (PKD1) gene reveals six novel mutations.Degradation of functional triose phosphate isomerase protein underlies sugarkill pathology.Early mitochondrial dysfunction leads to altered redox chemistry underlying pathogenesis of TPI deficiency.Premature translation termination mediates triosephosphate isomerase mRNA degradation.Evidence of a triosephosphate isomerase non-catalytic function crucial to behavior and longevityStructural analysis on mutation residues and interfacial water molecules for human TIM disease understandingA Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism.Hemolytic anemia and progressive neurologic impairment: think about triosephosphate isomerase deficiency.Molecular basis of erythroenzymopathies associated with hereditary hemolytic anemia: tabulation of mutant enzymes.The adaptive evolution divergence of triosephosphate isomerases between parasitic and free-living flatworms and the discovery of a potential universal target against flatworm parasites.Frequency and distribution of rare electrophoretic mobility variants in a population of human newborns in Ann Arbor, Michigan.Triose phosphate isomerase from the blood fluke Schistosoma mansoni: biochemical characterisation of a potential drug and vaccine target.Triosephosphate isomerase deficiency: repetitive occurrence of point mutation in amino acid 104 in multiple apparently unrelated families.Detection of the protein dimers, multiple monomeric states and hydrated forms of Plasmodium falciparum triosephosphate isomerase in the gas phase.Is the catalytic activity of triosephosphate isomerase fully optimized? An investigation based on maximization of entropy production.
P2860
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P2860
Human triose-phosphate isomerase deficiency: a single amino acid substitution results in a thermolabile enzyme
description
1986 nî lūn-bûn
@nan
1986 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1986 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
name
Human triose-phosphate isomera ...... sults in a thermolabile enzyme
@ast
Human triose-phosphate isomera ...... sults in a thermolabile enzyme
@en
Human triose-phosphate isomera ...... sults in a thermolabile enzyme
@en-gb
Human triose-phosphate isomera ...... sults in a thermolabile enzyme
@nl
type
label
Human triose-phosphate isomera ...... sults in a thermolabile enzyme
@ast
Human triose-phosphate isomera ...... sults in a thermolabile enzyme
@en
Human triose-phosphate isomera ...... sults in a thermolabile enzyme
@en-gb
Human triose-phosphate isomera ...... sults in a thermolabile enzyme
@nl
prefLabel
Human triose-phosphate isomera ...... sults in a thermolabile enzyme
@ast
Human triose-phosphate isomera ...... sults in a thermolabile enzyme
@en
Human triose-phosphate isomera ...... sults in a thermolabile enzyme
@en-gb
Human triose-phosphate isomera ...... sults in a thermolabile enzyme
@nl
P2093
P2860
P356
P1476
Human triose-phosphate isomera ...... sults in a thermolabile enzyme
@en
P2093
D C Phillips
L E Maquat
P J Artymiuk
P2860
P304
P356
10.1073/PNAS.83.20.7903
P407
P577
1986-10-01T00:00:00Z