Crystal structure of a complex between protein tyrosine phosphatase 1B and the insulin receptor tyrosine kinase
about
Receptor protein tyrosine phosphatase-receptor tyrosine kinase substrate screen identifies EphA2 as a target for LAR in cell migrationRegulation of the Met receptor-tyrosine kinase by the protein-tyrosine phosphatase 1B and T-cell phosphataseDruggability Assessment of Allosteric Proteins by Dynamics Simulations in the Presence of Probe MoleculesInsights into the Reaction of Protein-tyrosine Phosphatase 1B: CRYSTAL STRUCTURES FOR TRANSITION STATE ANALOGS OF BOTH CATALYTIC STEPSVisualizing Active-Site Dynamics in Single Crystals of HePTP: Opening of the WPD Loop Involves Coordinated Movement of the E LoopStructure-guided studies of the SHP-1/JAK1 interaction provide new insights into phosphatase catalytic domain substrate recognitionSubstrate specificity of protein tyrosine phosphatases 1B, RPTPα, SHP-1, and SHP-2.The Toxoplasma pseudokinase ROP5 is an allosteric inhibitor of the immunity-related GTPases.How IGF-1 activates its receptor.The insulin receptor: both a prototypical and atypical receptor tyrosine kinase.PTP1B is a negative regulator of interleukin 4-induced STAT6 signalingProtein tyrosine phosphatases: regulatory mechanisms.PTP1B: a double agent in metabolism and oncogenesis.Identification of receptor protein tyrosine phosphatases (RPTPs) as regulators of receptor tyrosine kinases (RTKs) using an RPTP siRNA-RTK substrate screen.Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.Design, synthesis, and evaluation of 2-(arylsulfonyl)oxiranes as cell-permeable covalent inhibitors of protein tyrosine phosphatases.Investigating the impact of Asp181 point mutations on interactions between PTP1B and phosphotyrosine substrate.Structural analysis of protein tyrosine phosphatase 1B reveals potentially druggable allosteric binding sites.Metabolic Pathways of the Warburg Effect in Health and Disease: Perspectives of Choice, Chain or Chance.Computational revelation of binding mechanisms of inhibitors to endocellular protein tyrosine phosphatase 1B using molecular dynamics simulations.Steered Molecular Dynamics for Investigating the Interactions Between Insulin Receptor Tyrosine Kinase (IRK) and Variants of Protein Tyrosine Phosphatase 1B (PTP1B).[Control of insulin signalisation and action by the Grb14 protein].
P2860
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P2860
Crystal structure of a complex between protein tyrosine phosphatase 1B and the insulin receptor tyrosine kinase
description
2005 nî lūn-bûn
@nan
2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Crystal structure of a complex ...... sulin receptor tyrosine kinase
@ast
Crystal structure of a complex ...... sulin receptor tyrosine kinase
@en
Crystal structure of a complex ...... sulin receptor tyrosine kinase
@en-gb
Crystal structure of a complex ...... sulin receptor tyrosine kinase
@nl
type
label
Crystal structure of a complex ...... sulin receptor tyrosine kinase
@ast
Crystal structure of a complex ...... sulin receptor tyrosine kinase
@en
Crystal structure of a complex ...... sulin receptor tyrosine kinase
@en-gb
Crystal structure of a complex ...... sulin receptor tyrosine kinase
@nl
prefLabel
Crystal structure of a complex ...... sulin receptor tyrosine kinase
@ast
Crystal structure of a complex ...... sulin receptor tyrosine kinase
@en
Crystal structure of a complex ...... sulin receptor tyrosine kinase
@en-gb
Crystal structure of a complex ...... sulin receptor tyrosine kinase
@nl
P2093
P921
P1433
P1476
Crystal structure of a complex ...... sulin receptor tyrosine kinase
@en
P2093
David Barford
Rafael S Depetris
Shiqing Li
P304
P356
10.1016/J.STR.2005.07.019
P407
P577
2005-11-01T00:00:00Z