d-Amino acid oxidase and serine racemase in human brain: normal distribution and altered expression in schizophrenia
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Peroxisomes in brain development and functionThe role of D-serine and glycine as co-agonists of NMDA receptors in motor neuron degeneration and amyotrophic lateral sclerosis (ALS)Serine racemase: a key player in apoptosis and necrosisTime and space profiling of NMDA receptor co-agonist functionsAntipsychotic drugs: comparison in animal models of efficacy, neurotransmitter regulation, and neuroprotectionNeonatal disruption of serine racemase causes schizophrenia-like behavioral abnormalities in adulthood: clinical rescue by d-serineThe association of schizophrenia risk D-amino acid oxidase polymorphisms with sensorimotor gating, working memory and personality in healthy males.Genetic loss of D-amino acid oxidase activity reverses schizophrenia-like phenotypes in mice.A role for D-aspartate oxidase in schizophrenia and in schizophrenia-related symptoms induced by phencyclidine in miceIn vivo magnetic resonance studies reveal neuroanatomical and neurochemical abnormalities in the serine racemase knockout mouse model of schizophrenia.Investigation of G72 (DAOA) expression in the human brain.Clinical and biochemical study of d-serine metabolism among schizophrenia patients.The neurobiology of D-amino acid oxidase and its involvement in schizophrenia.Decreased free d-aspartate levels are linked to enhanced d-aspartate oxidase activity in the dorsolateral prefrontal cortex of schizophrenia patientsActivity of D-amino acid oxidase is widespread in the human central nervous system.The role of D-amino acids in amyotrophic lateral sclerosis pathogenesis: a review.Schizophrenia drug discovery and development in an evolving era: are new drug targets fulfilling expectations?A novel pyridoxal 5'-phosphate-dependent amino acid racemase in the Aplysia californica central nervous system.The glutamate hypothesis of schizophrenia: evidence from human brain tissue studies.Alternative kynurenic acid synthesis routes studied in the rat cerebellum.D-serine and serine racemase are localized to neurons in the adult mouse and human forebrainKynurenic acid and 3-hydroxykynurenine production from D-kynurenine in mice.Haplotypes of the D-Amino Acid Oxidase Gene Are Significantly Associated with Schizophrenia and Its Neurocognitive Deficits.Association between SNPs and gene expression in multiple regions of the human brainAddressing the Conformational Flexibility of Serine Racemase by Combining Targeted Molecular Dynamics, Conformational Sampling and Docking Studies.Understanding renal nuclear protein accumulation: an in vitro approach to explain an in vivo phenomenon.d-amino acid oxidase knockout (Dao(-/-) ) mice show enhanced short-term memory performance and heightened anxiety, but no sleep or circadian rhythm disruption.D-Amino-Acid Oxidase Inhibition Increases D-Serine Plasma Levels in Mouse But not in Monkey or Dog.Biomarker investigations related to pathophysiological pathways in schizophrenia and psychosis.D-serine signalling as a prominent determinant of neuronal-glial dialogue in the healthy and diseased brainCerebrospinal fluid: identification of diagnostic markers for schizophrenia.Cerebrospinal fluid biomarker candidates of schizophrenia: where do we stand?D-serine and schizophrenia: an update.D-Amino acids in the brain and mutant rodents lacking D-amino-acid oxidase activity.The role of D-serine as co-agonist of NMDA receptors in the nucleus accumbens: relevance to cocaine addiction.D-amino acid oxidase activity is inhibited by an interaction with bassoon protein at the presynaptic active zone.The degradation (by distinct pathways) of human D-amino acid oxidase and its interacting partner pLG72--two key proteins in D-serine catabolism in the brain.D-amino acid oxidase is expressed in the ventral tegmental area and modulates cortical dopamine.D-Serine metabolism in C6 glioma cells: Involvement of alanine-serine-cysteine transporter (ASCT2) and serine racemase (SRR) but not D-amino acid oxidase (DAO).Supplementation with D-serine prevents the onset of cognitive deficits in adult offspring after maternal immune activation.
P2860
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P2860
d-Amino acid oxidase and serine racemase in human brain: normal distribution and altered expression in schizophrenia
description
2007 nî lūn-bûn
@nan
2007 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
d-Amino acid oxidase and serin ...... ed expression in schizophrenia
@ast
d-Amino acid oxidase and serin ...... ed expression in schizophrenia
@en
d-Amino acid oxidase and serin ...... ed expression in schizophrenia
@en-gb
d-Amino acid oxidase and serin ...... ed expression in schizophrenia
@nl
type
label
d-Amino acid oxidase and serin ...... ed expression in schizophrenia
@ast
d-Amino acid oxidase and serin ...... ed expression in schizophrenia
@en
d-Amino acid oxidase and serin ...... ed expression in schizophrenia
@en-gb
d-Amino acid oxidase and serin ...... ed expression in schizophrenia
@nl
prefLabel
d-Amino acid oxidase and serin ...... ed expression in schizophrenia
@ast
d-Amino acid oxidase and serin ...... ed expression in schizophrenia
@en
d-Amino acid oxidase and serin ...... ed expression in schizophrenia
@en-gb
d-Amino acid oxidase and serin ...... ed expression in schizophrenia
@nl
P2093
P2860
P921
P1476
d-Amino acid oxidase and serin ...... ed expression in schizophrenia
@en
P2093
Isabel Benzel
James N C Kew
Louise Verrall
Mary Walker
Nancy Rawlings
Paul J Harrison
P2860
P304
P356
10.1111/J.1460-9568.2007.05769.X
P407
P577
2007-09-01T00:00:00Z