Subgroup IV of human immunoglobulin K light chains is encoded by a single germline gene
about
Autoantibody-associated kappa light chain variable region gene expressed in chronic lymphocytic leukemia with little or no somatic mutation. Implications for etiology and immunotherapyDevelopment of a humanized monoclonal antibody with therapeutic potential against West Nile virusStructural relationship of kappa-type light chains with AL amyloidosis: multiple deletions found in a VkappaIV protein.A novel upstream element compensates for an ineffectual octamer motif in an immunoglobulin V kappa promoter.Evidence of antigen receptor-influenced oligoclonal B lymphocyte expansion in the synovium of a patient with longstanding rheumatoid arthritis.Structure of a monoclonal kappa chain of the V kappa IV subgroup in the kidney and plasma cells in light chain deposition disease.Nucleotidic sequence analysis of the variable domains of four human monoclonal IgM with an antibody activity to myelin-associated glycoprotein.Assembly of the kappa preB receptor requires a V kappa-like protein encoded by a germline transcript.N segment insertion and region-directed somatic hypermutation in a kappa gene of a t(2;8) chromosomal translocation.Sequences closely related to an immunoglobulin gene promoter/enhancer element occur also upstream of other eukaryotic and of prokaryotic genes.Upstream regulatory sequences of immunoglobulin genes are recognized by nuclear proteins which also bind to other gene regions.The human antibody V region repertoire to the type B capsular polysaccharide of Haemophilus influenzae.Somatic mutation and CDR3 lengths of immunoglobulin kappa light chains expressed in patients with rheumatoid arthritis and in normal individualsReciprocal recombination products of VK-JK joining reactions in human lymphoid cell lines.Induced rearrangement of kappa genes in the BLIN-1 human pre-B cell line correlates with germline J-C kappa and V kappa transcription.Molecular characteristics of antibodies bearing an anti-DNA-associated idiotype.Structure of the VH and VL segments of polyreactive and monoreactive human natural antibodies to HIV-1 and Escherichia coli beta-galactosidaseRecombinant immunoglobulin variable domains generated from synthetic genes provide a system for in vitro characterization of light-chain amyloid proteins.In situ hybridisation and S1 mapping show that the presence of infiltrating plasma cells is associated with poor prognosis in breast cancer.Human anti-self antibodies with high specificity from phage display libraries.Three breakpoints of variant t(2;8) translocations in Burkitt's lymphoma cells fall within a region 140 kilobases distal from c-myc.Influence of the light chain repertoire on immunoglobulin genes encoding thyroid autoantibody Fab from combinatorial libraries.Humanization of murine monoclonal antibodies through variable domain resurfacing.V region gene analysis of human IgM hybridoma monoclonal anti-Sm antibodies.Linking of the human immunoglobulin VK and JKCK regions by chromosomal walking.Physical map of the human immunoglobulin K locus and its implications for the mechanisms of VK-JK rearrangement.The human CK gene segment and the kappa deleting element are closely linked.The CDR1 sequences of a major proportion of human germline Ig VH genes are inherently susceptible to amino acid replacement.The structural repertoire of the human V kappa domainHuman lupus anti-DNA autoantibodies undergo essentially primary V kappa gene rearrangementsTracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sectionsGermline variable region gene segment derivation of human monoclonal anti-Rh(D) antibodies. Evidence for affinity maturation by somatic hypermutation and repertoire shift.A human chromosome 8 region with abnormalities in B cell, HTLV-I+ T cell and c-myc amplified tumours.Human B cell biology.Primary structure of a monoclonal kappa chain in myeloma with light chain deposition disease.Burkitt's lymphoma is a malignancy of mature B cells expressing somatically mutated V region genes.kappa+lambda+ dual receptor B cells are present in the human peripheral repertoireNotes on individual sequence variation in humans: immunoglobulin kappa light chain.AL kappa amyloid in a solitary extradural lymphoma.
P2860
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P2860
Subgroup IV of human immunoglobulin K light chains is encoded by a single germline gene
description
1985 nî lūn-bûn
@nan
1985 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1985 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1985年の論文
@ja
1985年論文
@yue
1985年論文
@zh-hant
1985年論文
@zh-hk
1985年論文
@zh-mo
1985年論文
@zh-tw
1985年论文
@wuu
name
Subgroup IV of human immunoglobulin K light chains is encoded by a single germline gene
@ast
Subgroup IV of human immunoglobulin K light chains is encoded by a single germline gene
@en
Subgroup IV of human immunoglobulin K light chains is encoded by a single germline gene
@en-gb
Subgroup IV of human immunoglobulin K light chains is encoded by a single germline gene
@nl
type
label
Subgroup IV of human immunoglobulin K light chains is encoded by a single germline gene
@ast
Subgroup IV of human immunoglobulin K light chains is encoded by a single germline gene
@en
Subgroup IV of human immunoglobulin K light chains is encoded by a single germline gene
@en-gb
Subgroup IV of human immunoglobulin K light chains is encoded by a single germline gene
@nl
prefLabel
Subgroup IV of human immunoglobulin K light chains is encoded by a single germline gene
@ast
Subgroup IV of human immunoglobulin K light chains is encoded by a single germline gene
@en
Subgroup IV of human immunoglobulin K light chains is encoded by a single germline gene
@en-gb
Subgroup IV of human immunoglobulin K light chains is encoded by a single germline gene
@nl
P2093
P2860
P356
P1476
Subgroup IV of human immunoglobulin K light chains is encoded by a single germline gene
@en
P2093
G Combriato
G W Bornkamm
H D Pohlenz
H G Klobeck
H G Zachau
P2860
P304
P356
10.1093/NAR/13.18.6515
P407
P577
1985-09-25T00:00:00Z