HECT E3 ubiquitin ligase Nedd4-1 ubiquitinates ACK and regulates epidermal growth factor (EGF)-induced degradation of EGF receptor and ACK
about
Shepherding AKT and androgen receptor by Ack1 tyrosine kinaseConstitutive activated Cdc42-associated kinase (Ack) phosphorylation at arrested endocytic clathrin-coated pits of cells that lack dynaminModulation of morphogenesis by Egfr during dorsal closure in DrosophilaMutations in TNK2 in severe autosomal recessive infantile onset epilepsy.PTEN is a protein tyrosine phosphatase for IRS1ACK1 tyrosine kinase: targeted inhibition to block cancer cell proliferationDrosophila activated Cdc42 kinase has an anti-apoptotic functionCortactin is a substrate of activated Cdc42-associated kinase 1 (ACK1) during ligand-induced epidermal growth factor receptor downregulationThe Cdc42-associated kinase ACK1 is not autoinhibited but requires Src for activation.Cytoplasmic FANCA-FANCC complex interacts and stabilizes the cytoplasm-dislocalized leukemic nucleophosmin protein (NPMc)Nedd4-1 is an exceptional prognostic biomarker for gastric cardia adenocarcinoma and functionally associated with metastasis.Mutational analysis of the tyrosine kinome in serous and clear cell endometrial cancer uncovers rare somatic mutations in TNK2 and DDR1Regulation of ack-family nonreceptor tyrosine kinases.NEDD4-1 regulates migration and invasion of glioma cells through CNrasGEF ubiquitination in vitro.Structural insights into the functional versatility of WW domain-containing oxidoreductase tumor suppressor.Nedd4-dependent lysine-11-linked polyubiquitination of the tumour suppressor Beclin 1.Molecular mechanisms of ubiquitin-dependent membrane trafficEndosomal type Iγ PIP 5-kinase controls EGF receptor lysosomal sortingTargeting CBLB as a potential therapeutic approach for disseminated candidiasis.Differential protein stability of EGFR mutants determines responsiveness to tyrosine kinase inhibitors.The non-receptor tyrosine kinase TNK2/ACK1 is a novel therapeutic target in triple negative breast cancer.Endosomal transport via ubiquitinationCopy number gains of FGFR1 and 3q chromosome in squamous cell carcinoma of the lung.SIAH ubiquitin ligases target the nonreceptor tyrosine kinase ACK1 for ubiquitinylation and proteasomal degradation.A genomic survey of HECT ubiquitin ligases in eukaryotes reveals independent expansions of the HECT system in several lineages.SAG/RBX2 is a novel substrate of NEDD4-1 E3 ubiquitin ligase and mediates NEDD4-1 induced chemosensitization.The HECT E3 ubiquitin ligase NEDD4 interacts with and ubiquitylates SQSTM1 for inclusion body autophagy.The E3 ubiquitin ligase NEDD4 mediates cell migration signaling of EGFR in lung cancer cells.The E3 ubiquitin ligase NEDD4 is an LC3-interactive protein and regulates autophagy.The Rab1 in host cells modulates Brucella intracellular survival and binds to Brucella DnaK protein.
P2860
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P248
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P2860
HECT E3 ubiquitin ligase Nedd4-1 ubiquitinates ACK and regulates epidermal growth factor (EGF)-induced degradation of EGF receptor and ACK
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
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2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
HECT E3 ubiquitin ligase Nedd4 ...... dation of EGF receptor and ACK
@ast
HECT E3 ubiquitin ligase Nedd4 ...... dation of EGF receptor and ACK
@en
HECT E3 ubiquitin ligase Nedd4 ...... dation of EGF receptor and ACK
@en-gb
HECT E3 ubiquitin ligase Nedd4 ...... dation of EGF receptor and ACK
@nl
type
label
HECT E3 ubiquitin ligase Nedd4 ...... dation of EGF receptor and ACK
@ast
HECT E3 ubiquitin ligase Nedd4 ...... dation of EGF receptor and ACK
@en
HECT E3 ubiquitin ligase Nedd4 ...... dation of EGF receptor and ACK
@en-gb
HECT E3 ubiquitin ligase Nedd4 ...... dation of EGF receptor and ACK
@nl
prefLabel
HECT E3 ubiquitin ligase Nedd4 ...... dation of EGF receptor and ACK
@ast
HECT E3 ubiquitin ligase Nedd4 ...... dation of EGF receptor and ACK
@en
HECT E3 ubiquitin ligase Nedd4 ...... dation of EGF receptor and ACK
@en-gb
HECT E3 ubiquitin ligase Nedd4 ...... dation of EGF receptor and ACK
@nl
P2093
P2860
P921
P3181
P356
P1476
HECT E3 ubiquitin ligase Nedd4 ...... dation of EGF receptor and ACK
@en
P2093
Chandra Childress
David J Carey
Marius Sudol
Wannian Yang
P2860
P304
P3181
P356
10.1128/MCB.00013-10
P407
P50
P577
2010-01-19T00:00:00Z