Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119.
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The interplay between RPGR, PDEδ and Arl2/3 regulate the ciliary targeting of farnesylated cargoGolgi Fragmentation in ALS Motor Neurons. New Mechanisms Targeting Microtubules, Tethers, and Transport VesiclesMolecular complexes that direct rhodopsin transport to primary ciliaStructural insights into the small G-protein Arl13B and implications for Joubert syndromePDE6δ-mediated sorting of INPP5E into the cilium is determined by cargo-carrier affinityDaughter cell identity emerges from the interplay of Cdc42, septins, and exocytosisHabenular commissure formation in zebrafish is regulated by the pineal gland-specific gene unc119cMembrane protein transport in photoreceptors: the function of PDEδ: the Proctor lectureCiliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanismThe solution structure of the transducin-α-uncoordinated 119 protein complex suggests occlusion of the Gβ₁γ₁-binding sites.The ARL2 GTPase is required for mitochondrial morphology, motility, and maintenance of ATP levels.Mistrafficking of prenylated proteins causes retinitis pigmentosa 2.The abundance of the ARL2 GTPase and its GAP, ELMOD2, at mitochondria are modulated by the fusogenic activity of mitofusins and stressors.Arf-like Protein 3 (ARL3) Regulates Protein Trafficking and Ciliogenesis in Mouse Photoreceptors.Mutations in ARL2BP, encoding ADP-ribosylation-factor-like 2 binding protein, cause autosomal-recessive retinitis pigmentosaProtein sorting, targeting and trafficking in photoreceptor cellsARL3 regulates trafficking of prenylated phototransduction proteins to the rod outer segment.Higher order signaling: ARL2 as regulator of both mitochondrial fusion and microtubule dynamics allows integration of 2 essential cell functions.Allosteric regulation of Arf GTPases and their GEFs at the membrane interface.A homozygous PDE6D mutation in Joubert syndrome impairs targeting of farnesylated INPP5E protein to the primary cilium.The Interaction of CCDC104/BARTL1 with Arl3 and Implications for Ciliary Function.GTP-binding of ARL-3 is activated by ARL-13 as a GEF and stabilized by UNC-119.Spatial cycles mediated by UNC119 solubilisation maintain Src family kinases plasma membrane localisation.Novel Biochemical and Structural Insights into the Interaction of Myristoylated Cargo with Unc119 Protein and Their Release by Arl2/3.Effect of the N-Terminal Helix and Nucleotide Loading on the Membrane and Effector Binding of Arl2/3.Sorting of lipidated cargo by the Arl2/Arl3 systemA G-protein activation cascade from Arl13B to Arl3 and implications for ciliary targeting of lipidated proteins.A GDI/GDF-like system for sorting and shuttling ciliary proteins.The guanine nucleotide exchange factor Arf-like protein 13b is essential for assembly of the mouse photoreceptor transition zone and outer segment.Characterization of a novel RP2-OSTF1 interaction and its implication for actin remodeling.Myristoylated NPHP3 translocates into the ciliary membraneArl3 and LC8 regulate dissociation of dynactin from dynein.Intrinsic properties and plasma membrane trafficking route of Src family kinase SH4 domains sensitive to retargeting by HIV-1 Nef.Specificity of Lipoprotein Chaperones for the Characteristic Lipidated Structural Motifs of their Cognate LipoproteinsThe Ciliary Machinery Is Repurposed for T Cell Immune Synapse Trafficking of LCK
P2860
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P2860
Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119.
description
2012 nî lūn-bûn
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2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
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2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
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name
Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119
@nl
Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119.
@ast
Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119.
@en
Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119.
@en-gb
type
label
Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119
@nl
Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119.
@ast
Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119.
@en
Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119.
@en-gb
prefLabel
Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119
@nl
Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119.
@ast
Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119.
@en
Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119.
@en-gb
P2093
P2860
P3181
P356
P1433
P1476
Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119.
@en
P2093
Carolin Koerner
Ingrid R Vetter
Mandy Miertzschke
Yong-Xiang Chen
P2860
P304
P3181
P356
10.1038/EMBOJ.2012.257
P407
P577
2012-09-07T00:00:00Z