MASTL is the human orthologue of Greatwall kinase that facilitates mitotic entry, anaphase and cytokinesis
about
Checkpoint recovery in cells: how a molecular understanding can help in the fight against cancerThe overlooked greatwall: a new perspective on mitotic controlLB100, a small molecule inhibitor of PP2A with potent chemo- and radio-sensitizing potentialModulation of cell cycle control during oocyte-to-embryo transitionsLoss of the Greatwall Kinase Weakens the Spindle Assembly CheckpointLive imaging RNAi screen reveals genes essential for meiosis in mammalian oocytes.PP2A-twins is antagonized by greatwall and collaborates with polo for cell cycle progression and centrosome attachment to nuclei in drosophila embryosSuppression of scant identifies Endos as a substrate of greatwall kinase and a negative regulator of protein phosphatase 2A in mitosisA first generation inhibitor of human Greatwall kinase, enabled by structural and functional characterisation of a minimal kinase domain constructProtein Phosphatases Involved in Regulating Mitosis: Facts and HypothesesMastl is required for timely activation of APC/C in meiosis I and Cdk1 reactivation in meiosis IIHybrid and rogue kinases encoded in the genomes of model eukaryotes.Mitotic progression becomes irreversible in prometaphase and collapses when Wee1 and Cdc25 are inhibitedBypassing the Greatwall-Endosulfine pathway: plasticity of a pivotal cell-cycle regulatory module in Drosophila melanogaster and Caenorhabditis elegans.Cell cycle regulation of Greatwall kinase nuclear localization facilitates mitotic progressionGreatwall is essential to prevent mitotic collapse after nuclear envelope breakdown in mammals.Identification and functional analysis of variant haplotypes in the 5'-flanking region of protein phosphatase 2A-Bδ gene.Entry into mitosis: a solution to the decades-long enigma of MPFα-endosulfine (ENSA) regulates exit from prophase I arrest in mouse oocytesNovel screening cascade identifies MKK4 as key kinase regulating Tau phosphorylation at Ser422.Phosphatase 1 nuclear targeting subunit is an essential regulator of M-phase entry, maintenance, and exitIdentification of a lifespan extending mutation in the Schizosaccharomyces pombe cyclin gene clg1+ by direct selection of long-lived mutants.Mastl kinase, a promising therapeutic target, promotes cancer recurrence.Increased ARPP-19 expression is associated with hepatocellular carcinomaPP2A/B55 and Fcp1 regulate Greatwall and Ensa dephosphorylation during mitotic exit.Determinants for Substrate Specificity of Protein Phosphatase 2A.Beyond the dopamine receptor: regulation and roles of serine/threonine protein phosphatases.Monoclonal antibodies against Xenopus greatwall kinaseMASTL promotes cyclin B1 destruction by enforcing Cdc20-independent binding of cyclin B1 to the APC/C.Killing cells by targeting mitosisProtein phosphatases and their regulation in the control of mitosisThe lethal response to Cdk1 inhibition depends on sister chromatid alignment errors generated by KIF4 and isoform 1 of PRC1.Regulation of Greatwall kinase by protein stabilization and nuclear localizationIn silico discovery of mitosis regulation networks associated with early distant metastases in estrogen receptor positive breast cancers.Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines.Effects of phosphatase and proteasome inhibitors on Borealin phosphorylation and degradationDeciphering the New Role of the Greatwall/PP2A Pathway in Cell Cycle Control.A Wee1 checkpoint inhibits anaphase onset.Robust mitotic entry is ensured by a latching switchSpatial regulation of greatwall by Cdk1 and PP2A-Tws in the cell cycle
P2860
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P2860
MASTL is the human orthologue of Greatwall kinase that facilitates mitotic entry, anaphase and cytokinesis
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
MASTL is the human orthologue ...... ntry, anaphase and cytokinesis
@ast
MASTL is the human orthologue ...... ntry, anaphase and cytokinesis
@en
MASTL is the human orthologue ...... ntry, anaphase and cytokinesis
@en-gb
MASTL is the human orthologue ...... ntry, anaphase and cytokinesis
@nl
type
label
MASTL is the human orthologue ...... ntry, anaphase and cytokinesis
@ast
MASTL is the human orthologue ...... ntry, anaphase and cytokinesis
@en
MASTL is the human orthologue ...... ntry, anaphase and cytokinesis
@en-gb
MASTL is the human orthologue ...... ntry, anaphase and cytokinesis
@nl
prefLabel
MASTL is the human orthologue ...... ntry, anaphase and cytokinesis
@ast
MASTL is the human orthologue ...... ntry, anaphase and cytokinesis
@en
MASTL is the human orthologue ...... ntry, anaphase and cytokinesis
@en-gb
MASTL is the human orthologue ...... ntry, anaphase and cytokinesis
@nl
P921
P3181
P356
P1433
P1476
MASTL is the human orthologue ...... ntry, anaphase and cytokinesis
@en
P2093
Erik Voets
Rob M F Wolthuis
P304
P3181
P356
10.4161/CC.9.17.12832
P407
P577
2010-09-01T00:00:00Z