Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol
about
A new view of the lethal apoptotic poreBAX unleashed: the biochemical transformation of an inactive cytosolic monomer into a toxic mitochondrial poreThe BCL2 Family: Key Mediators of the Apoptotic Response to Targeted Anticancer TherapeuticsIntegration and oligomerization of Bax protein in lipid bilayers characterized by single molecule fluorescence studyStructural mechanism of Bax inhibition by cytomegalovirus protein vMIABID-induced structural changes in BAK promote apoptosisBioactive lipids and the control of Bax pro-apoptotic activityBuilding blocks of the apoptotic pore: how Bax and Bak are activated and oligomerize during apoptosisMinimalist Model Systems Reveal Similarities and Differences between Membrane Interaction Modes of MCL1 and BAKBax activation initiates the assembly of a multimeric catalyst that facilitates Bax pore formation in mitochondrial outer membranesQuercetin potentiates doxorubicin mediated antitumor effects against liver cancer through p53/Bcl-xlNatural borneol, a monoterpenoid compound, potentiates selenocystine-induced apoptosis in human hepatocellular carcinoma cells by enhancement of cellular uptake and activation of ROS-mediated DNA damageTranscriptome sequencing of tumor subpopulations reveals a spectrum of therapeutic options for squamous cell lung cancerEndoplasmic reticulum stress sensitizes pancreatic beta cells to interleukin-1β-induced apoptosis via Bim/A1 imbalanceIdentification of Bax-interacting proteins in oligodendrocyte progenitors during glutamate excitotoxicity and perinatal hypoxia-ischemiaConformation of BCL-XL upon Membrane IntegrationFrom computational modelling of the intrinsic apoptosis pathway to a systems-based analysis of chemotherapy resistance: achievements, perspectives and challenges in systems medicine.Mst1 promotes cardiac myocyte apoptosis through phosphorylation and inhibition of Bcl-xLLoss of BAX by miR-365 Promotes Cutaneous Squamous Cell Carcinoma Progression by Suppressing ApoptosisThe rheostat in the membrane: BCL-2 family proteins and apoptosisArtesunate induces apoptosis via a Bak-mediated caspase-independent intrinsic pathway in human lung adenocarcinoma cells.Delivery of a monomeric p53 subdomain with mitochondrial targeting signals from pro-apoptotic Bak or Bax.Dynamic interaction of cBid with detergents, liposomes and mitochondria.Phosphorylation of Rad9 at serine 328 by cyclin A-Cdk2 triggers apoptosis via interfering Bcl-xLBax targets mitochondria by distinct mechanisms before or during apoptotic cell death: a requirement for VDAC2 or Bak for efficient Bax apoptotic functionBlockade of the BAK hydrophobic groove by inhibitory phosphorylation regulates commitment to apoptosis.Conformational rearrangements in the pro-apoptotic protein, Bax, as it inserts into mitochondria: a cellular death switch.Levels of pro-apoptotic regulator Bad and anti-apoptotic regulator Bcl-xL determine the type of the apoptotic logic gate.Synergistic induction of apoptosis in A549 cells by dihydroartemisinin and gemcitabine.IIIDB: a database for isoform-isoform interactions and isoform network modules.Mitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics.The Role of BH3-Only Proteins in Tumor Cell Development, Signaling, and Treatment.Synergistic efficacy of a novel combination therapy controls growth of Bcl-x(L) bountiful neuroblastoma cells by increasing differentiation and apoptosis.CHCHD2 inhibits apoptosis by interacting with Bcl-x L to regulate Bax activation.Altered mitochondrial apoptotic pathway in placentas from undernourished rat gestations.Mitochondria and apoptosis: emerging concepts.Wip1 promotes RUNX2-dependent apoptosis in p53-negative tumors and protects normal tissues during treatment with anticancer agentsTranslocation of a Bak C-terminus mutant from cytosol to mitochondria to mediate cytochrome C release: implications for Bak and Bax apoptotic function.Bcl-2 family in inter-organelle modulation of calcium signaling; roles in bioenergetics and cell survival.Resveratrol protects PC12 cells against OGD/ R-induced apoptosis via the mitochondrial-mediated signaling pathway
P2860
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P2860
Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol
@ast
Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol
@en
Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol
@en-gb
Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol
@nl
type
label
Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol
@ast
Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol
@en
Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol
@en-gb
Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol
@nl
prefLabel
Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol
@ast
Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol
@en
Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol
@en-gb
Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol
@nl
P2093
P2860
P50
P3181
P1433
P1476
Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol
@en
P2093
Damien Arnoult
Frank Edlich
Motoshi Suzuki
Nico Tjandra
Richard J Youle
Soojay Banerjee
P2860
P304
P3181
P356
10.1016/J.CELL.2011.02.034
P407
P577
2011-04-01T00:00:00Z