Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure
about
Gq/11-mediated signaling and hypertrophy in mice with cardiac-specific transgenic expression of regulator of G-protein signaling 2Striatin assembles a membrane signaling complex necessary for rapid, nongenomic activation of endothelial NO synthase by estrogen receptor alphaGeneration and characterization of Rgs4 mutant miceA crystal structure of the cyclic GMP-dependent protein kinase I{beta} dimerization/docking domain reveals molecular details of isoform-specific anchoringDeregulation of RGS2 in cardiovascular diseasesNitric oxide-induced biphasic mechanism of vascular relaxation via dephosphorylation of CPI-17 and MYPT1The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunitsMechanisms of Vascular Smooth Muscle Contraction and the Basis for Pharmacologic Treatment of Smooth Muscle DisordersRegulator of G Protein Signaling 2: A Versatile Regulator of Vascular FunctionPI3Kγ in hypertension: a novel therapeutic target controlling vascular myogenic tone and target organ damageNogo-B regulates endothelial sphingolipid homeostasis to control vascular function and blood pressureThe C. elegans cGMP-dependent protein kinase EGL-4 regulates nociceptive behavioral sensitivityWhole-Genome Sequencing of Native Sheep Provides Insights into Rapid Adaptations to Extreme Environments.Structural diversity in the RGS domain and its interaction with heterotrimeric G protein -subunitsStructural Determinants of G-protein Subunit Selectivity by Regulator of G-protein Signaling 2 (RGS2)Regulators of G-protein signaling in the heart and their potential as therapeutic targets.The Multifaceted Roles of PI3Kγ in Hypertension, Vascular Biology, and InflammationFormin homology domain protein (FHOD1) is a cyclic GMP-dependent protein kinase I-binding protein and substrate in vascular smooth muscle cellsThe RGS2 (-391, C>G) genetic variation correlates to antihypertensive drug responses in Chinese patients with essential hypertensionIdentification of a cAMP-response element in the regulator of G-protein signaling-2 (RGS2) promoter as a key cis-regulatory element for RGS2 transcriptional regulation by angiotensin II in cultured vascular smooth musclesRegulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in miceIdentification of genes and networks driving cardiovascular and metabolic phenotypes in a mouse F2 intercrossStructure of the Regulator of G Protein Signaling 8 (RGS8)-Gαq Complex: MOLECULAR BASIS FOR Gα SELECTIVITY.Thromboxane A2-induced bi-directional regulation of cerebral arterial tone.Regulator of G protein signaling 2 deficiency causes endothelial dysfunction and impaired endothelium-derived hyperpolarizing factor-mediated relaxation by dysregulating Gi/o signalingVascular microarray profiling in two models of hypertension identifies caveolin-1, Rgs2 and Rgs5 as antihypertensive targets.Natriuretic Peptide Signaling via Guanylyl Cyclase (GC)-A: An Endogenous Protective Mechanism of the Heart.Regulation of the cGMP-cPKG pathway and large-conductance Ca2+-activated K+ channels in uterine arteries during the ovine ovarian cyclemiR-374 promotes myocardial hypertrophy by negatively regulating vascular endothelial growth factor receptor-1 signaling.Upregulation of regulator of G-protein signaling 2 in the sclera of a form deprivation myopic animal modelNovel insights into the mechanisms mediating the local antihypertrophic effects of cardiac atrial natriuretic peptide: role of cGMP-dependent protein kinase and RGS2.L-arginine as a nutritional prophylaxis against vascular endothelial dysfunction with aging.17Beta-estradiol elevates cGMP and, via plasma membrane recruitment of protein kinase GIalpha, stimulates Ca2+ efflux from rat hepatocytes.RGS5 promotes arterial growth during arteriogenesisRegulators of G-protein signaling and their Gα substrates: promises and challenges in their use as drug discovery targets.Promoter Polymorphism of RGS2 Gene Is Associated with Change of Blood Pressure in Subjects with Antihypertensive Treatment: The Azelnidipine and Temocapril in Hypertensive Patients with Type 2 Diabetes Study.cGMP-dependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action.Regulation of GPCR signaling in hypertension.Regulation of Gβγi-dependent PLC-β3 activity in smooth muscle: inhibitory phosphorylation of PLC-β3 by PKA and PKG and stimulatory phosphorylation of Gαi-GTPase-activating protein RGS2 by PKG.The myriad essential roles of microRNAs in cardiovascular homeostasis and disease.
P2860
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P2860
Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure
description
2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Regulator of G-protein signali ...... relaxation and blood pressure
@ast
Regulator of G-protein signali ...... relaxation and blood pressure
@en
Regulator of G-protein signali ...... relaxation and blood pressure
@en-gb
Regulator of G-protein signali ...... relaxation and blood pressure
@nl
type
label
Regulator of G-protein signali ...... relaxation and blood pressure
@ast
Regulator of G-protein signali ...... relaxation and blood pressure
@en
Regulator of G-protein signali ...... relaxation and blood pressure
@en-gb
Regulator of G-protein signali ...... relaxation and blood pressure
@nl
prefLabel
Regulator of G-protein signali ...... relaxation and blood pressure
@ast
Regulator of G-protein signali ...... relaxation and blood pressure
@en
Regulator of G-protein signali ...... relaxation and blood pressure
@en-gb
Regulator of G-protein signali ...... relaxation and blood pressure
@nl
P2093
P921
P3181
P356
P1433
P1476
Regulator of G-protein signali ...... relaxation and blood pressure
@en
P2093
Guang-rong Wang
K Mary Tang
Kendall J Blumer
Kevin M Kaltenbronn
Mark Aronovitz
Michael E Mendelsohn
Richard H Karas
Scott P Heximer
P2888
P304
P3181
P356
10.1038/NM958
P407
P577
2003-11-09T00:00:00Z
P5875
P6179
1005094251