Naturally occurring variants of human aldo-keto reductases with reduced in vitro metabolism of daunorubicin and doxorubicin
about
Protective effect of 23-hydroxybetulinic acid on doxorubicin-induced cardiotoxicity: a correlation with the inhibition of carbonyl reductase-mediated metabolismInterindividual variability in the cardiac expression of anthracycline reductases in donors with and without Down syndrome.Genetic polymorphisms in oxidative stress-related genes are associated with outcomes following treatment for aggressive B-cell non-Hodgkin lymphomaGenetic variability in the metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) to 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL).Correlation of aldo-ketoreductase (AKR) 1C3 genetic variant with doxorubicin pharmacodynamics in Asian breast cancer patients.A study to investigate dose escalation of doxorubicin in ABVD chemotherapy for Hodgkin lymphoma incorporating biomarkers of response and toxicity.Pharmacogenetics of genes across the doxorubicin pathway.Role of Drug Metabolism in the Cytotoxicity and Clinical Efficacy of Anthracyclines.Metabolic carbonyl reduction of anthracyclines - role in cardiotoxicity and cancer resistance. Reducing enzymes as putative targets for novel cardioprotective and chemosensitizing agents.Successful recovery and allogeneic stem cell transplant following chemotherapy-induced severe cardiomyopathy: literature review of management and prognostic factors.Aldo-Keto Reductase 1B10 and Its Role in Proliferation Capacity of Drug-Resistant CancersProtective effects of berberine against doxorubicin-induced cardiotoxicity in rats by inhibiting metabolism of doxorubicin.Impact of nonsynonymous single nucleotide polymorphisms on in-vitro metabolism of exemestane by hepatic cytosolic reductases.Detoxifying Enzymes at the Cross-Roads of Inflammation, Oxidative Stress, and Drug Hypersensitivity: Role of Glutathione Transferase P1-1 and Aldose Reductase.Pharmacogenetics of aldo-keto reductase 1C (AKR1C) enzymes.AKRs expression in peripheral blood lymphocytes from smokers: the role of body mass index.Genetic variants inSLC22A17 and SLC22A7are associated with anthracycline-induced cardiotoxicity in children
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P2860
Naturally occurring variants of human aldo-keto reductases with reduced in vitro metabolism of daunorubicin and doxorubicin
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Naturally occurring variants o ...... f daunorubicin and doxorubicin
@ast
Naturally occurring variants o ...... f daunorubicin and doxorubicin
@en
Naturally occurring variants o ...... f daunorubicin and doxorubicin
@en-gb
Naturally occurring variants o ...... f daunorubicin and doxorubicin
@nl
type
label
Naturally occurring variants o ...... f daunorubicin and doxorubicin
@ast
Naturally occurring variants o ...... f daunorubicin and doxorubicin
@en
Naturally occurring variants o ...... f daunorubicin and doxorubicin
@en-gb
Naturally occurring variants o ...... f daunorubicin and doxorubicin
@nl
prefLabel
Naturally occurring variants o ...... f daunorubicin and doxorubicin
@ast
Naturally occurring variants o ...... f daunorubicin and doxorubicin
@en
Naturally occurring variants o ...... f daunorubicin and doxorubicin
@en-gb
Naturally occurring variants o ...... f daunorubicin and doxorubicin
@nl
P2093
P921
P3181
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P1476
Naturally occurring variants o ...... f daunorubicin and doxorubicin
@en
P2093
K Wayne Riggs
Onkar S Bains
Ronald E Reid
Thomas A Grigliatti
P304
P3181
P356
10.1124/JPET.110.173179
P407
P577
2010-12-01T00:00:00Z