Remodeling of channel-forming ORAI proteins determines an oncogenic switch in prostate cancer
about
Altered expression of stromal interaction molecule (STIM)-calcium release-activated calcium channel protein (ORAI) and inositol 1,4,5-trisphosphate receptors (IP3Rs) in cancer: will they become a new battlefield for oncotherapy?Epigenomic profiling of prostate cancer identifies differentially methylated genes in TMPRSS2:ERG fusion-positive versus fusion-negative tumors.Anti-proliferative Effects of Nucleotides on Gastric Cancer via a Novel P2Y6/SOCE/Ca2+/β-catenin Pathway.Calcium signals inhibition sensitizes ovarian carcinoma cells to anti-Bcl-xL strategies through Mcl-1 down-regulation.Translational horizons in the tumor microenvironment: harnessing breakthroughs and targeting cures.Stim and Orai proteins in neuronal Ca(2+) signaling and excitabilityCalcium Electroporation: Evidence for Differential Effects in Normal and Malignant Cell Lines, Evaluated in a 3D Spheroid Model.STIM1 accelerates cell senescence in a remodeled microenvironment but enhances the epithelial-to-mesenchymal transition in prostate cancerSTIM and Orai proteins as novel targets for cancer therapy. A Review in the Theme: Cell and Molecular Processes in Cancer Metastasis.Disrupting the dynamic equilibrium of ORAI channels determines the phenotype of malignant cellsOrai3 is a predictive marker of metastasis and survival in resectable lung adenocarcinoma.Open Sesame: treasure in store-operated calcium entry pathway for cancer therapySTIM and ORAI proteins: crucial roles in hallmarks of cancer.Bcl-2 proteins and calcium signaling: complexity beneath the surface.Regulation of Ca(2+) signaling in prostate cancer cells.Calcium Channel Blocker Use and Risk of Prostate Cancer by TMPRSS2:ERG Gene Fusion Status.Marchantin M Induces Apoptosis of Prostate Cancer Cells Through Endoplasmic Reticulum Stress.Differential Redox Regulation of Ca²⁺ Signaling and Viability in Normal and Malignant Prostate Cells.The endoplasmic reticulum mitochondrial calcium cross talk is downregulated in malignant pleural mesothelioma cells and plays a critical role in apoptosis inhibition.Targeting calcium signaling in cancer therapy.Crosstalk between calcium and reactive oxygen species signaling in cancer.Modulation of Ca2+ Signaling by Anti-apoptotic B-Cell Lymphoma 2 Proteins at the Endoplasmic Reticulum-Mitochondrial Interface.ORAI Calcium Channels.p53 and Ca(2+) signaling from the endoplasmic reticulum: partners in anti-cancer therapies.The prion protein constitutively controls neuronal store-operated Ca(2+) entry through Fyn kinase.The SigmaR1 chaperone drives breast and colorectal cancer cell migration by tuning SK3-dependent Ca2+ homeostasis.The oncogenic role of the In1-ghrelin splicing variant in prostate cancer aggressivenessOncosis and apoptosis induction by activation of an overexpressed ion channel in breast cancer cells.Orai3 Surface Accumulation and Calcium Entry Evoked by Vascular Endothelial Growth Factor.Orai1, 2, 3 and STIM1 promote store-operated calcium entry in pulmonary arterial smooth muscle cells.The store-operated calcium channels in cancer metastasis: from cell migration, invasion to metastatic colonization.Introduction: Overview of the Pathophysiological Implications of Store-Operated Calcium Entry in Mammalian Cells.The STIM-Orai Pathway: The Interactions Between STIM and Orai.Orai3 calcium channel and resistance to chemotherapy in breast cancer cells: the p53 connection.Selenoprotein K deficiency inhibits melanoma by reducing calcium flux required for tumor growth and metastasis.Calcium and Nuclear Signaling in Prostate Cancer.[A new oncogenic switch in prostate cancer progression: the exceptional ORAI3].Deregulation of calcium homeostasis in Bcr-Abl-dependent chronic myeloid leukemia.Arachidonic acid-induced Ca2+ entry and migration in a neuroendocrine cancer cell line.Store-Operated Ca2+ Entry as a Prostate Cancer Biomarker — a Riddle with Perspectives.
P2860
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P2860
Remodeling of channel-forming ORAI proteins determines an oncogenic switch in prostate cancer
description
2014 nî lūn-bûn
@nan
2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Remodeling of channel-forming ...... enic switch in prostate cancer
@ast
Remodeling of channel-forming ...... enic switch in prostate cancer
@en
Remodeling of channel-forming ...... enic switch in prostate cancer
@en-gb
Remodeling of channel-forming ...... enic switch in prostate cancer
@nl
type
label
Remodeling of channel-forming ...... enic switch in prostate cancer
@ast
Remodeling of channel-forming ...... enic switch in prostate cancer
@en
Remodeling of channel-forming ...... enic switch in prostate cancer
@en-gb
Remodeling of channel-forming ...... enic switch in prostate cancer
@nl
prefLabel
Remodeling of channel-forming ...... enic switch in prostate cancer
@ast
Remodeling of channel-forming ...... enic switch in prostate cancer
@en
Remodeling of channel-forming ...... enic switch in prostate cancer
@en-gb
Remodeling of channel-forming ...... enic switch in prostate cancer
@nl
P2093
P50
P3181
P1433
P1476
Remodeling of channel-forming ...... enic switch in prostate cancer
@en
P2093
Anne Sophie Borowiec
Basma Guarmit
Christian Slomianny
Fabien Vanden Abeele
Gilbert Lepage
Mohamed Benahmed
Yaroslav Shuba
P3181
P356
10.1016/J.CCR.2014.04.025
P407
P577
2014-06-19T00:00:00Z