Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR
about
Experimental therapies and ongoing clinical trials to slow down progression of ADPKDMutations in Traf3ip1 reveal defects in ciliogenesis, embryonic development, and altered cell size regulationGenetic control of renal tumorigenesis by the mouse Rtm1 locus.The cell biology of polycystic kidney diseaseKidney: polycystic kidney disease.Effect of PKD1 gene missense mutations on polycystin-1 membrane topogenesis.Cilium, centrosome and cell cycle regulation in polycystic kidney disease.Molecular pathways and therapies in autosomal-dominant polycystic kidney diseaseInsight into response to mTOR inhibition when PKD1 and TSC2 are mutatedPolycystin-1 Is a Cardiomyocyte Mechanosensor That Governs L-Type Ca2+ Channel Protein StabilityThe Akt signaling pathway is required for tissue maintenance and regeneration in planariansThe Future of Polycystic Kidney Disease Research--As Seen By the 12 Kaplan Awardees.Regulation of Polycystin-1 Function by Calmodulin Binding.Cystogenesis and elongated primary cilia in Tsc1-deficient distal convoluted tubules.Combined Deletion of Vhl and Kif3a Accelerates Renal Cyst FormationPediatric glioma-associated KIAA1549:BRAF expression regulates neuroglial cell growth in a cell type-specific and mTOR-dependent manner.mTORC1-mediated inhibition of polycystin-1 expression drives renal cyst formation in tuberous sclerosis complex.Tumor Suppressor Folliculin Regulates mTORC1 through Primary CiliaPrimary cilia and kidney injury: current research status and future perspectivesCalcium-mediated mechanisms of cystic expansion.Mammalian target of rapamycin and the kidney. II. Pathophysiology and therapeutic implications.Multidrug therapy for polycystic kidney disease: a review and perspective.Meckel-Gruber syndrome and the role of primary cilia in kidney, skeleton, and central nervous system developmentPolycystins and partners: proposed role in mechanosensitivity.Genetics and pathogenesis of autosomal dominant polycystic kidney disease: 20 years on.Novel therapeutic approaches to autosomal dominant polycystic kidney disease.Therapeutic targets for polycystic kidney disease.Genetic Mechanisms of ADPKD.Polycystin and calcium signaling in cell death and survival.New Roles of the Primary Cilium in Autophagy.Primary Cilium-Dependent Signaling Mechanisms.Inpp5e suppresses polycystic kidney disease via inhibition of PI3K/Akt-dependent mTORC1 signaling.
P2860
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P2860
Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR
description
2010 nî lūn-bûn
@nan
2010 թուականին հրատարակուած գիտական յօդուած
@hyw
2010 թվականին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR
@ast
Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR
@en
Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR
@en-gb
Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR
@nl
type
label
Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR
@ast
Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR
@en
Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR
@en-gb
Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR
@nl
prefLabel
Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR
@ast
Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR
@en
Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR
@en-gb
Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR
@nl
P2093
P2860
P3181
P1433
P1476
Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR
@en
P2093
Cheryl Lyn Walker
Patricia D Wilson
Richard N Sandford
Ruhee Dere
P2860
P3181
P356
10.1371/JOURNAL.PONE.0009239
P407
P577
2010-01-01T00:00:00Z