AIP1/DAB2IP, a novel member of the Ras-GAP family, transduces TRAF2-induced ASK1-JNK activation
about
Tumor necrosis factor alpha-induced desumoylation and cytoplasmic translocation of homeodomain-interacting protein kinase 1 are critical for apoptosis signal-regulating kinase 1-JNK/p38 activationRole of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis.An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappaBRIP1-mediated AIP1 phosphorylation at a 14-3-3-binding site is critical for tumor necrosis factor-induced ASK1-JNK/p38 activationAIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress responseDAB2IP coordinates both PI3K-Akt and ASK1 pathways for cell survival and apoptosisAIP1 functions as Arf6-GAP to negatively regulate TLR4 signalingA genome-scale protein interaction profile of Drosophila p53 uncovers additional nodes of the human p53 networkDAB2IP in cancerDab2IP GTPase activating protein regulates dendrite development and synapse number in cerebellumApoptosis of cholangiocytes modulated by thioredoxin of carcinogenic liver fluke.Reactive oxygen species, cellular redox systems, and apoptosisDab2ip regulates neuronal migration and neurite outgrowth in the developing neocortexA systems-biology analysis of isogenic megakaryocytic and granulocytic cultures identifies new molecular components of megakaryocytic apoptosis.Negative regulation of DAB2IP by Akt and SCFFbw7 pathwaysTargeting of tumor necrosis factor receptor 1 to low density plasma membrane domains in human endothelial cells.A common genetic variant (97906C>A) of DAB2IP/AIP1 is associated with an increased risk and early onset of lung cancer in Chinese males.The role of homeostatic regulation between tumor suppressor DAB2IP and oncogenic Skp2 in prostate cancer growth.Down-regulation of human DAB2IP gene expression mediated by polycomb Ezh2 complex and histone deacetylase in prostate cancer.SENP1 mediates TNF-induced desumoylation and cytoplasmic translocation of HIPK1 to enhance ASK1-dependent apoptosis.Downregulation of DAB2IP results in cell proliferation and invasion and contributes to unfavorable outcomes in bladder cancer.A review of the mammalian unfolded protein response.AIP1 prevents graft arteriosclerosis by inhibiting interferon-γ-dependent smooth muscle cell proliferation and intimal expansionDifferential functions of tumor necrosis factor receptor 1 and 2 signaling in ischemia-mediated arteriogenesis and angiogenesis.AIP1 in graft arteriosclerosisAbsence of DAB2IP promotes cancer stem cell like signatures and indicates poor survival outcome in colorectal cancerRas proteins: paradigms for compartmentalised and isoform-specific signalling.Early cellular signaling responses to axonal injury.AIP1 mediates vascular endothelial cell growth factor receptor-3-dependent angiogenic and lymphangiogenic responses.Nonredundant functions for Ras GTPase-activating proteins in tissue homeostasis.Oxidative stress: the mitochondria-dependent and mitochondria-independent pathways of apoptosis.AIP1-mediated stress signaling in atherosclerosis and arteriosclerosis.An update on the etiology of abdominal aortic aneurysms: implications for future diagnostic testing.Loss of DAB2IP in RCC cells enhances their growth and resistance to mTOR-targeted therapies.Expression of DAB2IP in human trophoblast and its role in trophoblast invasion.The ATM inhibitor KU55933 sensitizes radioresistant bladder cancer cells with DAB2IP gene defect.Liver fluke infection and cholangiocarcinoma: a review.Block one, unleash a hundred. Mechanisms of DAB2IP inactivation in cancer.A novel dual signaling axis for NSP 5a3a induced apoptosis in head and neck carcinoma.REDOX reaction at ASK1-Cys250 is essential for activation of JNK and induction of apoptosis.
P2860
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P2860
AIP1/DAB2IP, a novel member of the Ras-GAP family, transduces TRAF2-induced ASK1-JNK activation
description
2004 nî lūn-bûn
@nan
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
AIP1/DAB2IP, a novel member of ...... F2-induced ASK1-JNK activation
@ast
AIP1/DAB2IP, a novel member of ...... F2-induced ASK1-JNK activation
@en
AIP1/DAB2IP, a novel member of ...... F2-induced ASK1-JNK activation
@en-gb
AIP1/DAB2IP, a novel member of ...... F2-induced ASK1-JNK activation
@nl
type
label
AIP1/DAB2IP, a novel member of ...... F2-induced ASK1-JNK activation
@ast
AIP1/DAB2IP, a novel member of ...... F2-induced ASK1-JNK activation
@en
AIP1/DAB2IP, a novel member of ...... F2-induced ASK1-JNK activation
@en-gb
AIP1/DAB2IP, a novel member of ...... F2-induced ASK1-JNK activation
@nl
prefLabel
AIP1/DAB2IP, a novel member of ...... F2-induced ASK1-JNK activation
@ast
AIP1/DAB2IP, a novel member of ...... F2-induced ASK1-JNK activation
@en
AIP1/DAB2IP, a novel member of ...... F2-induced ASK1-JNK activation
@en-gb
AIP1/DAB2IP, a novel member of ...... F2-induced ASK1-JNK activation
@nl
P2093
P2860
P921
P356
P1476
AIP1/DAB2IP, a novel member of ...... F2-induced ASK1-JNK activation
@en
P2093
Alessio D'Alessio
Haifeng Zhang
Jordan S Pober
Rong Zhang
P2860
P304
P356
10.1074/JBC.M407617200
P407
P577
2004-10-22T00:00:00Z